University of Nevada, Reno

About: University of Nevada, Reno is a education organization based out in Reno, Nevada, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 13561 authors who have published 28217 publications receiving 882002 citations. The organization is also known as: University of Nevada & Nevada State University.

Physiology and Pathophysiology of the Interstitial Cell of Cajal: From Bench to Bedside I. Functional development and plasticity of interstitial cells of Cajal networks

Abstract: Interstitial cells of Cajal (ICC) are the pacemaker cells in gastrointestinal (GI) muscles. They also mediate or transduce inputs from enteric motor nerves to the smooth muscle syncytium. What is k...

Mobile Edge Computing Empowered Energy Efficient Task Offloading in 5G

Abstract: Mobile edge computing has been proposed in recent years to offload computation tasks from user equipments (UEs) to the network edge to break hardware limitations and resource constraints at UEs. Although there have been some existing works on computation offloading in 5G, most of them fail to take into account the unique property of 5G in their scheme design. In this paper, we consider small-cell network architecture for task offloading. In order to achieve energy efficiency, we model the energy consumption of offloading from both task computation and communication aspects. Besides, transmission scheduling are carried over both the fronthaul and backhaul links. We first formulate an energy optimization problem of offloading, which aims at minimizing the overall energy consumption at all system entities and takes into account of the constraints from both computation capabilities and service delay requirement. We then develop an artificial fish swarm algorithm based scheme to solve the energy optimization problem. Besides, the global convergence property of the our scheme is formally proven. Finally, various simulation results demonstrate the efficiency of our scheme.

Many X-linked microRNAs escape meiotic sex chromosome inactivation

Abstract: Meiotic sex chromosome inactivation (MSCI) during spermatogenesis is characterized by transcriptional silencing of genes on both the X and Y chromosomes in mid-to-late pachytene spermatocytes. MSCI is believed to result from meiotic silencing of unpaired DNA because the X and Y chromosomes remain largely unpaired throughout first meiotic prophase. However, unlike X-chromosome inactivation in female embryonic cells, where 25-30% of X-linked structural genes have been reported to escape inactivation, previous microarray- and RT-PCR-based studies of expression of >364 X-linked mRNA-encoding genes during spermatogenesis have failed to reveal any X-linked gene that escapes the silencing effects of MSCI in primary spermatocytes. Here we show that many X-linked miRNAs are transcribed and processed in pachytene spermatocytes. This unprecedented escape from MSCI by these X-linked miRNAs suggests that they may participate in a critical function at this stage of spermatogenesis, including the possibility that they contribute to the process of MSCI itself, or that they may be essential for post-transcriptional regulation of autosomal mRNAs during the late meiotic and early postmeiotic stages of spermatogenesis.

Opportunities for Research in Third-Party Logistics

Abstract: Third-party logistics (3PL), also known as "logistical outsourcing", is expanding from its origins in the 1980s to the point where opportunities for expanded research beyond exploratory investigations are growing. This article traces the history of leading research analysis and suggests that the present state of the field means that it is important to expand and advance it to support the needs of 3PL practitioners. A table describes the topics assessed in 3PL research, along with sample research questions and hypotheses for each. Additional tables give paper counts by journal, by year and topics addressed, all organized around the topics. Opportunities by topic and viewpoints, such as buyer vs. provider, are described, along with possible areas of focus: buyer size and power, buyer industry, buyer production and supply chain strategies, organization level, functional affiliation, length of service, 3PL age, size and services offered, as well as asset- vs. non-asset-based 3PL providers. Conclusions include the need for expanding into more advanced and alternative methodologies.