University of Nevada, Reno

About: University of Nevada, Reno is a education organization based out in Reno, Nevada, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 13561 authors who have published 28217 publications receiving 882002 citations. The organization is also known as: University of Nevada & Nevada State University.

Genetic-Algorithm-Based Optimization Approach for Energy Management

Abstract: This paper proposes a new strategy to meet the controllable heating, ventilation, and air conditioning (HVAC) load with a hybrid-renewable generation and energy storage system. Historical hourly wind speed, solar irradiance, and load data are used to stochastically model the wind generation, photovoltaic generation, and load. Using fuzzy C-Means (FCM) clustering, these data are grouped into 10 clusters of days with similar data points to account for seasonal variations. In order to minimize cost and increase efficiency, we use a GA-based optimization approach together with a two-point estimate method. Minimizing the cost function guarantees minimum PV and wind generation installation as well as storage capacity selection to supply the HVAC load. Different scenarios are examined to evaluate the efficiency of the system with different percentages of load shifting. The maximum capacity of the storage system and excess energy are calculated as the most important indices for energy efficiency assessment. The cumulative distribution functions of these indices are plotted and compared. A smart-grid strategy is developed for matching renewable energy generation (solar and wind) with the HVAC load.

The effect of queen pheromones on worker honey bee ovary development.

Abstract: We report results that address a long-standing controversy in honey bee biology, the identity of the queen-produced compounds that inhibit worker honey bee ovary development. As the honey bee is the only organism for which identities have been proposed for any pheromone that regulates reproduction, the resolution of its identity is of broad significance. We examined the effects of synthetic honey bee queen mandibular pheromone (QMP), four newly identified queen retinue pheromone components, and whole-queen extracts on the ovary development of caged worker bees. The newly identified compounds did not inhibit worker ovary development alone, nor did they improve the efficacy of QMP when applied in combination. QMP was as effective as queen extracts at ovary regulation. Caged workers in the QMP and queen extract treatments had better developed ovaries than did workers remaining in queenright colonies. We conclude that QMP is responsible for the ovary-regulating pheromonal capability of queens from European-derived Apis mellifera subspecies.

Transient Receptor Potential Channels in the Vasculature

Abstract: The mammalian genome encodes 28 distinct members of the transient receptor potential (TRP) superfamily of cation channels, which exhibit varying degrees of selectivity for different ionic species. Multiple TRP channels are present in all cells and are involved in diverse aspects of cellular function, including sensory perception and signal transduction. Notably, TRP channels are involved in regulating vascular function and pathophysiology, the focus of this review. TRP channels in vascular smooth muscle cells participate in regulating contractility and proliferation, whereas endothelial TRP channel activity is an important contributor to endothelium-dependent vasodilation, vascular wall permeability, and angiogenesis. TRP channels are also present in perivascular sensory neurons and astrocytic endfeet proximal to cerebral arterioles, where they participate in the regulation of vascular tone. Almost all of these functions are mediated by changes in global intracellular Ca2+ levels or subcellular Ca2+ signaling events. In addition to directly mediating Ca2+ entry, TRP channels influence intracellular Ca2+ dynamics through membrane depolarization associated with the influx of cations or through receptor- or store-operated mechanisms. Dysregulation of TRP channels is associated with vascular-related pathologies, including hypertension, neointimal injury, ischemia-reperfusion injury, pulmonary edema, and neurogenic inflammation. In this review, we briefly consider general aspects of TRP channel biology and provide an in-depth discussion of the functions of TRP channels in vascular smooth muscle cells, endothelial cells, and perivascular cells under normal and pathophysiological conditions.

Nutritional genomics: manipulating plant micronutrients to improve human health.

Abstract: The nutritional health and well-being of humans are entirely dependent on plant foods either directly or indirectly when plants are consumed by animals. Plant foods provide almost all essential vitamins and minerals and a number of other health-promoting phytochemicals. Because micronutrient concentrations are often low in staple crops, research is under way to understand and manipulate synthesis of micronutrients in order to improve crop nutritional quality. Genome sequencing projects are providing novel approaches for identifying plant biosynthetic genes of nutritional importance. The term "nutritional genomics" is used to describe work at the interface of plant biochemistry, genomics, and human nutrition.