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Showing papers by "University of New Mexico published in 1972"


Journal ArticleDOI
TL;DR: A schema of treatment of the three types of acromioclavicular injuries, based on pathological change in each, is presented and results in both acute and chronic cases have been quite good.
Abstract: A schema of treatment of the three types of acromioclavicular injuries, based [See table in the PDF file] on pathological change in each, is presented. Type-I injuries are those with direct trauma to the acromioclavicular joint without significant ligamentous tears or intability. Type-II injuries are those with acromioclavicular ligamentous injury and instability but without disruption of the coracoclavicular ligaments. Type-III injuries are those with complete clavicular instability and disruption of both sets of ligaments. Type-I injuries are treated expectantly when seen early, and when seen late, with acromioclavicular arthritis, they are treated by resection arthroplasty. Expectant treatment is advocated for early Type-II injuries while late symptomatic Type-II separations are treated by resection arthroplasty of the acromioclavicular joint. Those patients with acute and chronic Type-III injuries are treated surgically by a new operation which combines resection arthroplasty of the acromioclavicular joint with fixation of the clavicle in an anatomical position by suture of the acromial end of the shortened coraco-acromial ligaments into the medullary canal of the clavicle. The results in both acute and chronic cases, fifteen in number, have been quite good.

573 citations


Book ChapterDOI
TL;DR: The available evidence suggests that the reaction of Enz·(AA ∼ AMP) with tRNA in vitro is so slow and incomplete that this reaction fails by a factor of a hundred or a thousand to account for the in vitro esterification of tRNA or the in vivo rate of protein synthesis.
Abstract: Publisher Summary This chapter reviews the discovery of the amino acid: tRNA ligases and the discovery of transfer ribonucleic acid. Each of the techniques for estimating the kinetic parameters of the ligases is critically reviewed and a comprehensive tabulation of all the chemical and physical properties of the purified enzymes is presented. The physiological concentrations of enzyme and tRNA, and the association constants of these macromolecules suggest that essentially the entire enzyme is present in the cell as Enz·tRNA complex. In several cases, the tRNA-free enzyme is totally unable to form Enz·(AA ∼ AMP). In other cases, the kinetic parameters of the Enz·tRNA complex are as different from those of the free enzyme as to make studies on the free enzyme difficult to interpret. The available evidence suggests that the reaction of Enz·(AA ∼ AMP) with tRNA in vitro is so slow and incomplete that this reaction fails by a factor of a hundred or a thousand to account for the in vitro esterification of tRNA or the in vivo rate of protein synthesis. The generally accepted mechanism of tRNA esterification is not acceptable for many amino acids and is of doubtful application in other cases. It is probable that in the unphysiological absence of tRNA these ligases do catalyze the synthesis of Enz·(AA ∼ AMP), but this complex is not ordinarily an intermediate in protein synthesis.

195 citations


Journal ArticleDOI
01 Feb 1972-Cancer
TL;DR: Though the specific agent responsible for paraplegia following intrathecal chemotherapy is unknown, there is evidence to suggest that the preservatives rather than the therapeutic agents themselves are responsible.
Abstract: A case report and review of the literature of paraplegia following intrathecal chemotherapy with methotrexate and cytosine arabinoside is presented. Autopsy identified damage to the spinal nerve roots within the subarachnoid space, which accounted for the neurologic deficit. The only substances common to both chemotherapeutic agents were their preservatives, methylhydroxybenzoate and benzyl alcohol, which were used, in the diluent. Prolonged exposure to these preservatives is known to cause severe neurotoxicity. Though the specific agent responsible for paraplegia following intrathecal chemotherapy is unknown, there is evidence to suggest that the preservatives rather than the therapeutic agents themselves are responsible.

174 citations


Journal ArticleDOI
TL;DR: In this article, the influence of a forest on the formation of steps in two small streams of the Colorado Rocky Mountains was studied, and it was shown that the average step length between logs and gravel bars was strongly related to channel gradient and median bed material size.
Abstract: The influence of a forest on the formation of steps in two small streams of the Colorado Rocky Mountains was studied. Steps provided by logs fallen across the channel added to flow energy reduction. The streams required additional gravel bars to adjust to slope. Average step length between logs and gravel bars was strongly related to channel gradient and median bed material size. Based on the average number of log steps per 50 feet of channel, an average of 116 percent of gravel bars were added at Fool Creek and 60 percent at Deadhorse Creek. The latter had 52 percent more logs in the channel and therefore required less bed material movement than the former. Although these are “rushing mountain streams,” most flow velocities ranged between 0.5 and 2.5 f.p.s. Exponents of a function relating rate of change of depth or velocity to discharge indicated that dynamic stream equilibrium was attained. Implications for forest management are that sanitation cuts (removal of dead and dying trees) would not be permissible where a stream is in dynamic equilibrium and bed material movement should be minimized.

141 citations


Journal ArticleDOI
TL;DR: Most bats with low aspect ratio are forest dwellers, whereas species with high aspect ratios are migrants and foragers in open areas.
Abstract: A method was devised for estimating aspect ratio, wing ratio, wing area, wing loading, and wing length from study skins of bats. These measures were taken of 136 species representing 15 families. Wing area and loading are positively, and wing length negatively, correlated with size. Aspect and tip ratios are independent of size and of each other. Distinctive combinations of some of these variables characterize groups of bats that presumably have similar flight modes. Speed is positively correlated with aspect ratio and tip index, but regresses significantly only on the former. Long tips coupled with low aspect ratio may characterize hoverers. Long wings and short tips may characterize bats that are capable of remaining airborne at slow speeds. Most bats with low aspect ratios are forest dwellers, whereas species with high aspect ratios are migrants and foragers in open areas.

128 citations


Journal ArticleDOI
TL;DR: In this article, the authors measured the varve couplets in the Castile and Salado formations in the Delaware Basin and found that they are synchronous, and each couplet is interpreted as representing an annual layer of sedimentation.
Abstract: Laminations in the Upper Permian evaporite sequence in the Delaware Basin appear in the preevaporite phase of the uppermost Bell Canyon Formation as alternations of siltstone and organic layers. The laminations then change character and composition upward to organically laminated claystone, organically laminated calcite, the calcite-laminated anhydrite typical of the Castile Formation, and finally to the anhydrite-laminated halite of the Castile and Salado. Laminae are correlative for distances up to 113 km (70.2 mi) and probably throughout most of the basin. Each lamina is synchronous, and each couplet of two laminated components is interpreted as representing an annual layer of sedimentation—a varve. The thickness of each couplet in the 260,000-varve sequence (a total thickness of 447.2 m, 1467 ft) has been measured individually and recorded and provides the basis for subdividing and correlating major stratigraphic units within the basin. The uppermost 9.2 m (30.3 ft) of the Bell Canyon Formation contains about 50,850 varve couplets; the Basal Limestone Member of the Castile about 600; the lowermost anhydrite member of the Castile (Anhydrite I) contains 38,397; Halite I, 1,063; Anhydrite II, 14,414; Halite II, 1,758; Anhydrite III, 46,592; Halite III, 17,879; and Anhydrite IV, 54,187. The part of the Salado collected (126.6 m) contains 35,422 varve couplets. The Bell Canyon-Castile sequence in the cores studied is apparently continuous, with no recognizable unconformities. The dominant petrologic oscillation in the Castile and Salado, other than the laminations, is a change from thinner undisturbed anhydrite laminae to thicker anhydrite laminae that generally show a secondary or penecontem-poraneous nodular character, with about 1,000 to 3,000 units between major oscillations or nodular beds. These nodular zones are correlative throughout the area of study and underly halite when it is present. The halite layers alternate with anhydrite laminae, are generally recrystallized, and have an average thickness of about 3 cm. The halite beds were once west of their present occurrence in the basin but were dissolved, leaving beds of anhydrite breccia. The onset and cessation of halite deposition in the basin was nearly synchronous. The Anhydrite I and II Members thicken gradually across the basin from west to east, whereas the Halite I, II, and III Members are thickest in the eastern and northeastern part of the basin and thicken from southeast to northwest. This distribution and the synchroneity indicate a departure from the classical model of evaporite zonation.

111 citations


Journal ArticleDOI
TL;DR: The results suggest that adrenergic denervation supersensitivity to catecholamines may be mediated by adenyl cyclase, and 6-hydroxydopamine treatment with either 250 μg per day or a control solution is recommended.

94 citations



Journal ArticleDOI
TL;DR: Despite the decrease in skin reactivity during influenza, phytohemagglutinin stimulated the lymphocytes of the four patients who were studied during both the acute and convalescent phases as well as after immunization against influenza in four patients.
Abstract: Eleven patients with influenzalike illnesses were skin tested with tuberculin, histoplasmin, coccidioidin, trichophytin, and Candida antigens during the acute phase of their illness and again one month later. Seven patients had serologically proven influenza and four had noninfluenzal febrile respiratory diseases. Only the group with influenza manifested significant hyporeactivity to the skin-test antigens during illness. Despite the decrease in skin reactivity during influenza, phytohemagglutinin stimulated the lymphocytes of the four patients who were studied during both the acute and convalescent phases. No decrease in skin-test reactivity was observed after immunization against influenza in four patients.

66 citations


Journal ArticleDOI
TL;DR: No difference was found between controls and patients with RA either in antigen frequency or quantity of the HL-A antigens on the lymphocytes.
Abstract: The frequency of HL-A antigens found in a group of patients with rheumatoid arthritis (RA) was compared with that found in a nonarthritic “normal” population. An attempt was also made to quantitate the relative amounts of HL-A antigens on lymphocytes of patients with RA as compared to control subjects' lymphocytes using three different HL-A antisera. No difference was found between controls and patients with RA either in antigen frequency or quantity of the HL-A antigens on the lymphocytes.

63 citations


Journal ArticleDOI
TL;DR: This article found that prior listener-experience with the voice of the speaker appears to be a prominent factor in intelligibility, indicating that accommodation to the speaker over time is a crucial variable, and that language teachers are apt to be the poorest judges of their students' ability to communicate with strangers.
Abstract: An experiment using dictation in foreign and native accents of English suggests that this is a fruitful device for the study of individual and group differences affecting mutual intelligibility. Prior listener-experience with the voice of the speaker appears to be a prominent factor in intelligibility, indicating that accommodation to the speaker over time is a crucial variable, and that language teachers are apt to be the poorest judges of their students’ability to communicate with strangers. A combination of age, education, and ESL teaching experience seems to increase ability to comprehend unfamiliar speakers. Bilingual Spanish-English listeners have an advantage in decoding Spanish-accented English, while American Indians scored below ESL students in ability to decode a heavy Spanish accent. Neither clear nor noise-contaminated tapes showed consistent superiority in maximizing discrimination among listener groups.

Journal ArticleDOI
TL;DR: A self-control procedure to improve study habits was taught to 38 volunteer students at the University of New Mexico summer school and showed a significant gain in grade point average (G.P.A.) for the three semesters following the study over the two preceding semesters.

Journal ArticleDOI
TL;DR: The physician must be alert to the relatively rare occurrence of a pheochromocytoma in a patient who presents with a primary cardiomyopathy or unexplained congestive heart failure, since removal of the tumor allows for regression, if not cure, of the associated heart disease.

Journal ArticleDOI
TL;DR: In this article, it was suggested that the textures observed would also result from rapid crystallization of relatively slowly cooling molten droplets that may have been produced in larger scale events, including condensation from a nebula of solar composition and solidification in an ambient medium of high temperature.

Journal ArticleDOI
TL;DR: This paper found that modeling can affect the complexity of children's sentences even in the absence of reinforcement or instructions to imitate, and that the effect of modeling on the length and complexity of a children's sentence was independent of grade level.


Journal ArticleDOI
TL;DR: In rheumatoid synovial fluids the percentage of lymphocytes carrying immunoglobulin appeared to be significantly higher than in peripheral blood from the same patients, and C3 receptor were almost always present on the same cells, indicating that the latter also is a marker for B lymphocytes.
Abstract: In peripheral blood of patients with rheumatoid arthritis the percentages of lymphocytes carrying surface-bound IgG, IgA or IgM did not differ significantly from those in normal controls. However, both the sum of these percentages and the percentage of cells carrying receptors for human C3 were significantly lower than in normal controls. Immunoglobulin and C3 receptor were almost always present on the same cells, indicating that the latter also is a marker for B lymphocytes. In rheumatoid synovial fluids the percentage of lymphocytes carrying immunoglobulin appeared to be significantly higher than in peripheral blood from the same patients. No similar difference was observed for the percentage of cells carrying C3 receptors, probably due to impaired detection of this receptor in some of the fluids.

Journal ArticleDOI
TL;DR: In this paper, the bulk compositions of igneous and microbreccia lithic fragments, glasses and chondrules from Luna 16 fines and of the compositions of minerals in basaltic lithic fragment were determined.

Journal ArticleDOI
TL;DR: In this article, a variable criterion model has been applied to data from an RT experiment by LaBerge in which catch trial stimuli varied in similarity to a single auditory RT signal, and estimates of a sensory recruitment function and the parameters of hypothetical criterion distributions were obtained by a scaling solution.
Abstract: A variable criterion model has been applied to data from an RT experiment by LaBerge in which catch trial stimuli varied in similarity to a single auditory RT signal. Estimates of a sensory recruitment function and the parameters of hypothetical criterion distributions were obtained by a scaling solution. Auditory recruitment was an exponential growth function, and the criterion distributions were normal. In combination, these estimates successfully predicted the empirical RT distributions.

Journal ArticleDOI
TL;DR: Two-hour isotopic 45calcium absorption measurements were determined in 23 thyrotoxic patients, 27 normal subjects, and in 10 treated hyperthyroid patients, showing clear defects in calcium absorption.

Journal ArticleDOI
TL;DR: In this paper, it was shown that if Tn is the transitive tournament on n points then c(Tn) = {log 2 n} but [((n + 1)2] colors suffice if the color classes are required to be oriented trees.

Journal ArticleDOI
TL;DR: The Dirichlet problem for equation (I) as discussed by the authors requires the determination of a solution u(x, y) of (1) in a domain D, taking on assigned continuous data on the boundary of D. In the case H = 0, this problem was solved by RAP6 [18] in 1930 for D convex.
Abstract: where w==V l + u~ + u ~ and Fu = (ux, u,). The Dirichlet problem for equation (I) requires the determination of a solution u(x, y) of (1) in a domain D, taking on assigned continuous data on the boundary of D. In the case H = 0, this problem was solved by RAP6 [18] in 1930 for D convex. FINN [5] showed that the restriction to convex domains is essential. However, the problem for constant H was only recently settled by SEm~aN [20]. Again considering the minimal surface case, JENKINS & SERRIN [11], in a very elegant paper, treated a much more general version of the Dirichlet problem. They developed an existence and uniqueness theory in which infinite boundary data are allowed on entire arcs of the boundary. The most interesting example of a minimal surface having in-

Journal ArticleDOI
TL;DR: During development of the rabbit cerebral cortex, the first detectable increase of cyclic AMP in response to histamine occurred at fetal day 25, and from day 28 to birth the response was a 4‐to 5‐fold increase, and by 20 days of postnatal age the response had decreased to the adult levels.
Abstract: — In slices of adult rabbit cerebral cortex histamine at 5 μM produced a detectable rise in adenosine 3′,5′-monophosphate (cyclic AMP). A maximum (20-fold) increase was observed in response to 0–5 mM histamine, with higher concentrations being less effective. The antihistaminic agent, tripelennamine, inhibited the response to 50 μM histamine in a dose-related manner. No effect on basal levels of cyclic AMP was noted with the highest dose of tripelennamine. The cyclic AMP response to 50 μM histamine was sustained for up to 1 h of incubation whether the slices and included medium were assayed together or the slices were assayed separately, although after 60 min of incubation cyclic AMP levels were higher when the medium was included in the assay. During development of the rabbit cerebral cortex, the first detectable increase of cyclic AMP in response to histamine occurred at fetal day 25, and from day 28 to birth the response was a 4-to 5-fold increase. A maximal (10-fold) response was observed at 4–8 days postpartum and by 20 days of postnatal age the response had decreased to the adult levels.

Journal ArticleDOI
TL;DR: The Landes silicate-bearing octahedrite is a new find from Grant County, West Virginia as discussed by the authors, and its compositions are very similar to those in Odessa-type silicate inclusions.
Abstract: The Landes silicate-bearing octahedrite is a new find from Grant County, West Virginia. Minerals and their compositions are very similar to those in Odessa-type silicate inclusions. The angular nature of the inclusions, recrystallization textures, and mineral compositions indicate a 'xenolithic' origin for the inclusions.

Journal ArticleDOI
TL;DR: Light microscopic and ultrastructural investigations in a case of systemic storage disease in an adult revealed lipofusein to be the stored substance in all cells involved and no lipid bodies or cytosomes characteristic for any storage disease were found.
Abstract: Light microscopic and ultrastructural investigations in a case of systemic storage disease in an adult revealed lipofusein to be the stored substance in all cells involved. No lipid bodies or cytosomes characteristic for any storage disease were found. Similarly there were no structures which could be interpreted as transitional stages of such bodies into lipofusein. Cases like this might be considered as a nosologic entity but the possibility that they might be a manifestation of a yet undiscovered metabolic derangement, in particular a lipidosis, cannot be excluded.

Journal ArticleDOI
TL;DR: Quantitation shows that spermine catalyzes the overall reaction of aminoacylation of tRNA without catalyzing ATP:PPi exchange, which is incompatible with the obligatory intermediate formation of Enz·(AA∼AMP) and PPi in the biosynthesis of AA-tRNA.


Journal ArticleDOI
TL;DR: A simple, rapid, and highly versatile thin-layer system is described for separating purine and pyrimidine nucleotides from their respective nucleosides and free bases, which retains both ribonucleotides and deoxyribonucleOTides at the origin and permits ribon nucleoside, deoxy Ribonucleosides, andfree bases to migrate away.