University of New Mexico

About: University of New Mexico is a education organization based out in Albuquerque, New Mexico, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 28870 authors who have published 64767 publications receiving 2578371 citations. The organization is also known as: UNM & Universitatis Novus Mexico.

Intrusion detection using sequences of system calls

Abstract: A method is introduced for detecting intrusions at the level of privileged processes. Evidence is given that short sequences of system calls executed by running processes are a good discriminator between normal and abnormal operating characteristics of several common UNIX programs. Normal behavior is collected in two waysc Synthetically, by exercising as many normal modes of usage of a program as possible, and in a live user environment by tracing the actual execution of the program. In the former case several types of intrusive behavior were studieds in the latter case, results were analyzed for false positives.

A Unified Field Approach for Heat Conduction From Macro- to Micro-Scales

Abstract: A universal constitutive equation between the heat flux vector and the temperature gradient is proposed to cover the fundamental behaviors of diffusion (macroscopic in both space and time), wave (macroscopic in space but microscopic in time), phonon-electron interactions (microscopic in both space and time), and pure phonon scattering The model is generalized from the dual-phase-lag concept accounting for the laging behavior in the high-rate response While the phase lag of the heat flux captures the small-scale response in time, the phase lag of the temperature gradient captures the small-scale response in space The universal form of the energy equation facilitates identifications of the physical parameters governing the transition from one mechanism (such as diffusion or wave) to another (the phonon-electron interaction)

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Abstract: Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP ALL cases and assessed the frequency of the identified somatic mutations in 94 T-cell acute lymphoblastic leukaemia cases. ETP ALL was characterized by activating mutations in genes regulating cytokine receptor and RAS signalling (67% of cases; NRAS, KRAS, FLT3, IL7R, JAK3, JAK1, SH2B3 and BRAF), inactivating lesions disrupting haematopoietic development (58%; GATA3, ETV6, RUNX1, IKZF1 and EP300) and histone-modifying genes (48%; EZH2, EED, SUZ12, SETD2 and EP300). We also identified new targets of recurrent mutation including DNM2, ECT2L and RELN. The mutational spectrum is similar to myeloid tumours, and moreover, the global transcriptional profile of ETP ALL was similar to that of normal and myeloid leukaemia haematopoietic stem cells. These findings suggest that addition of myeloid-directed therapies might improve the poor outcome of ETP ALL.

Complex and oriented ZnO nanostructures

Abstract: Extended and oriented nanostructures are desirable for many applications, but direct fabrication of complex nanostructures with controlled crystalline morphology, orientation and surface architectures remains a significant challenge. Here we report a low-temperature, environmentally benign, solution-based approach for the preparation of complex and oriented ZnO nanostructures, and the systematic modification of their crystal morphology. Using controlled seeded growth and citrate anions that selectively adsorb on ZnO basal planes as the structure-directing agent, we prepared large arrays of oriented ZnO nanorods with controlled aspect ratios, complex film morphologies made of oriented nanocolumns and nanoplates (remarkably similar to biomineral structures in red abalone shells) and complex bilayers showing in situ column-to-rod morphological transitions. The advantages of some of these ZnO structures for photocatalytic decompositions of volatile organic compounds were demonstrated. The novel ZnO nanostructures are expected to have great potential for sensing, catalysis, optical emission, piezoelectric transduction, and actuations.

Motivational Interviewing with Problem Drinkers

Abstract: Motivational interviewing is an approach based upon principles of experimental social psychology, applying processes such as attribution, cognitive dissonance, and self-efficacy. Motivation is conceptualized not as a personality trait but as an interpersonal process. The model deemphasizes labeling and places heavy emphasis on individual responsibility and internal attribution of change. Cognitive dissonance is created by contrasting the ongoing problem behavior with salient awareness of the behavior's negative consequences. Empathic processes from the methods of Carl Rogers, social psychological principles of motivation, and objective assessment feedback are employed to channel this dissonance toward a behavior change solution, avoiding the “short circuits” of low self-esteem, low self-efficacy, and denial. This motivational process is understood within a larger developmental model of change in which contemplation and determination are important early steps which can be influenced by therapist interventions. A schematic diagram of the motivational process and a six-step sequence for implementing motivational interviewing are suggested.