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Institution

University of Nice Sophia Antipolis

EducationNice, France
About: University of Nice Sophia Antipolis is a education organization based out in Nice, France. It is known for research contribution in the topics: Population & Stars. The organization has 10291 authors who have published 19964 publications receiving 680762 citations. The organization is also known as: UNS & University of Nice-Sophia Antipolis.
Topics: Population, Stars, Planet, Galaxy, Adipose tissue


Papers
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Proceedings ArticleDOI
01 Nov 2012
TL;DR: Examining two easy-to-handle conditions that allow to examine how the stability limit varies as a function of the step-size, the kernel bandwidth, and the filter length allows to greatly simplify calculations.
Abstract: In addition to the choice of the usual linear adaptive filter parameters, designing kernel adaptive filters requires the choice of the kernel and its parameters One of our recent works has brought a new contribution to the discussion about kernel-based adaptive filtering by providing the first convergence analysis of the kernel-LMS algorithm with Gaussian kernel A necessary and sufficient condition for convergence has been clearly established Checking the stability of the algorithm can, unfortunately, be computationally expensive because one needs to calculate the extreme eigenvalues of a large matrix, for each set of candidate tuning parameters The aim of this paper is to circumvent this drawback by examining two easy-to-handle conditions that allow to examine how the stability limit varies as a function of the step-size, the kernel bandwidth, and the filter length One of them is a conjectured necessary and sufficient condition for convergence that allows to greatly simplify calculations

13 citations

Journal ArticleDOI
TL;DR: An overview of the contradictory roles that autophagy plays in cancer initiation and progression is provided and the promises and challenges of current strategies that target autophagic for cancer therapy are discussed.
Abstract: Survival rates of patients with metastatic or recurrent cancers have remained virtually unchanged during the past 30 years. This fact makes the need for new therapeutic options even more urgent. An attractive option would be to target autophagy, an essential quality control process that degrades toxic aggregates, damaged organelles, and signaling proteins, and acts as a tumor suppressor pathway of tumor initiation. Conversely, other fascinating observations suggest that autophagy supports cancer progression, relapse, metastasis, dormancy and resistance to therapy. This review provides an overview of the contradictory roles that autophagy plays in cancer initiation and progression and discusses the promises and challenges of current strategies that target autophagy for cancer therapy.

13 citations

Journal ArticleDOI
01 Aug 2001-Networks
TL;DR: It is shown that BB is achieved in time at most 2n in any n‐node network and networks in which time 2n − o(n) is needed and algorithms working in time (2 + ϵ)n, for any fixed positive constant ϵ and sufficiently large n are shown.
Abstract: We consider the problem of disseminating messages in networks. We are interested in information dissemination algorithms in which machines operate independently without any knowledge of the network topology or size. Three communication tasks of increasing difficulty are studied. In blind broadcasting (BB), the goal is to communicate the source message to all nodes. In acknowledged blind broadcasting (ABB), the goal is to achieve BB and inform the source about it. Finally, in full synchronization (FS), all nodes must simultaneously enter the state terminated after receiving the source message. The algorithms should be efficient both in terms of the time required and the communication overhead they put on the network. We limit the latter by allowing every node to send a message to at most one neighbor in each round. We show that BB is achieved in time at most 2n in any n-node network and show networks in which time 2n − o(n) is needed. For ABB, we show algorithms working in time (2 + ϵ)n, for any fixed positive constant ϵ and sufficiently large n. Thus, for both BB and ABB, our algorithms are close to optimal. Finally, we show a simple algorithm for FS working in time 3n and a more complicated algorithm which works in time 2.9n. The optimal time of full synchronization remains an open problem. © 2001 John Wiley & Sons, Inc.

13 citations

Journal ArticleDOI
TL;DR: The main finding was that during submaximal cycling energetically optimal cadence or neuromuscular optimum in trained cyclists was significantly related with strength capacity and whereas preferred cadence seems to be related with endurance training status of cyclists.
Abstract: The purpose of this study was to examine the relationship between strength capacity and preferred and optimal cadence in well trained cyclists. Eighteen cyclists participated in this study. Each subject completed three sessions. The initial session was to evaluate the maximal isokinetic voluntary contraction level of lower limb. The second session was an incremental test to exhaustion. During the third session subjects performed a constant cycling exercise (20 min) conducted at five randomly cadences (50, 70, 90, 110 rpm) and at the preferred cadence (FCC) at the power reached at ventilatory threshold. Cardiorespiratory and EMG values were recorded. A metabolic optimum (EOC) was observed at 63.5 +/- 7.8 rpm different from preferred cadence (FCC, 90.6 +/- 9.1 rpm). No difference was found between FCC and the neuromuscular optimal cadence (NOC, 93.5 +/- 4). Significant relationships were found between EOC, NOC and strength capacities (r = - 0.75 and - 0. 63), whereas FCC was only related with VO2max (r = 0.59). The main finding of this study was that during submaximal cycling energetically optimal cadence or neuromuscular optimum in trained cyclists was significantly related with strength capacity and whereas preferred cadence seems to be related with endurance training status of cyclists.

13 citations

Journal ArticleDOI
TL;DR: Correlations are rare between the evolution of organelles and cellular inclusions observed during the growth and the diet.
Abstract: Summary The Intestines of the Mugilidae (Pisces Teleostei) at different growth stages. II-Ultrastructural and cytophysiological aspects The ultrastructures and functions of the columnar cells of the intestinal epithelia are characterized, from the larva to the adult stage: major transformations of the endoplasmatic reticulum, passage of SER/RER from 1 to 3, noticeable encrease of Golgi activity, development of lamellar structures forming a “mitochondrial pump” together with the basal mitochondria, at all levels of the intestine. Localized mainly in the posterior region of the juvenil stages, pinocytosis of the alimentary proteins and the associated lytic processus extend in the adult to the anterior region. Lipid absorption takes place essentially in the anterior part, resulting at all stages of development in the presence of lipid particles in the SER and in the intercellular spaces, and in the adult only in rare free lipid droplets in the cytoplasma. Correlations are rare between the evolution of organelles and cellular inclusions observed during the growth and the diet.

13 citations


Authors

Showing all 10355 results

NameH-indexPapersCitations
Robert J. Lefkowitz214860147995
Johan Auwerx15865395779
Kenneth M. Yamada13944672136
Jean-Luc Starck13365776224
Christophe Benoist13247063181
Jacques Pouysségur12541254656
Michel Lazdunski12556254650
E. A. De Wolf124133383171
Leon O. Chua12282471612
Tomasz Bulik12169886211
James G. Krueger12050546275
Austin Smith11130163156
Peter Fritschel10842772722
Didier Sornette104129544157
François Bondu10044069284
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202310
2022139
2021202
2020264
2019441
2018536