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Showing papers by "University of Nigeria, Nsukka published in 2014"


Journal ArticleDOI
TL;DR: Combining both microorganisms and plants is an approach to bioremediation that ensures a more efficient clean-up of heavy metal polluted soils as discussed by the authors, however, success of this approach largely depends on the species of organisms involved in the process.
Abstract: Soils polluted with heavy metals have become common across the globe due to increase in geologic and anthropogenic activities. Plants growing on these soils show a reduction in growth, performance, and yield. Bioremediation is an effective method of treating heavy metal polluted soils. It is a widely accepted method that is mostly carried out in situ; hence it is suitable for the establishment/reestablishment of crops on treated soils. Microorganisms and plants employ different mechanisms for the bioremediation of polluted soils. Using plants for the treatment of polluted soils is a more common approach in the bioremediation of heavy metal polluted soils. Combining both microorganisms and plants is an approach to bioremediation that ensures a more efficient clean-up of heavy metal polluted soils. However, success of this approach largely depends on the species of organisms involved in the process.

833 citations


Journal ArticleDOI
Charles N. Rotimi1, Akin Abayomi2, Alash'le Abimiku3, Victoria Adabayeri4  +242 moreInstitutions (82)
20 Jun 2014-Science
TL;DR: If the dearth of genomics research involving Africans persists, the potential health and economic benefits emanating from genomic science may elude an entire continent.
Abstract: H3Africa is developing capacity for health-related genomics research in Africa Our understanding of genome biology, genomics, and disease, and even human history, has advanced tremendously with the completion of the Human Genome Project. Technological advances coupled with significant cost reductions in genomic research have yielded novel insights into disease etiology, diagnosis, and therapy for some of the world's most intractable and devastating diseases—including malaria, HIV/AIDS, tuberculosis, cancer, and diabetes. Yet, despite the burden of infectious diseases and, more recently, noncommunicable diseases (NCDs) in Africa, Africans have only participated minimally in genomics research. Of the thousands of genome-wide association studies (GWASs) that have been conducted globally, only seven (for HIV susceptibility, malaria, tuberculosis, and podoconiosis) have been conducted exclusively on African participants; four others (for prostate cancer, obsessive compulsive disorder, and anthropometry) included some African participants (www.genome.gov/gwastudies/). As discussed in 2011 (www.h3africa.org), if the dearth of genomics research involving Africans persists, the potential health and economic benefits emanating from genomic science may elude an entire continent.

344 citations


Journal ArticleDOI
TL;DR: Evidence is generally provided of profound anti-inflammatory activity of β-amyrin and α- amyrin acetate isolated from the Alstonia boonei stem bark.
Abstract: Context: Alstonia boonei De Wild (Apocyanaceae) is used in ethnomedicine for the management of malaria, ulcer, rhematic pain, toothache, and inflammatory disorders.Objective: To investigate the anti-inflammatory potential of β-amyrin and α-amyrin acetate isolated from the stem bark of Alstonia boonei using animal models.Materials and methods: Chromatographic purification of the crude methanol extract led to the isolation and structure elucidation of β-amyrin and α-amyrin acetate. Their anti-inflammatory activities were evaluated in rodents using egg albumen-induced paw edema and xylene-induced ear edema models. The gastric ulcerogenic, in vivo leucocyte migration, and RBC membrane stabilization tests were also investigated.Results: α-Amyrin acetate at 100 mg/kg showed significant (p 0.01) irritation of the gastric mucosa while significant...

132 citations


Journal ArticleDOI
TL;DR: In this paper, the authors highlight some important developments in, and potentials of algaculture as a major biomass resource of the future, however, the major constraint to commercial-scale algae farming for energy production is the cost factor, which must be addressed adequately before its potentials can be harnessed.

126 citations


Journal ArticleDOI
TL;DR: TbA QP2 mediates high-affinity uptake of pentamidine and melaminophenyl arsenicals in trypanosomes and TbAQP2 encodes the previously reported HAPT1 activity, which establishes Tb aQP 2 as an important drug transporter.
Abstract: Trypanosoma brucei drug transporters include the TbAT1/P2 aminopurine transporter and the high-affinity pentamidine transporter (HAPT1), but the genetic identity of HAPT1 is unknown. We recently reported that loss of T. brucei aquaglyceroporin 2 (TbAQP2) caused melarsoprol/pentamidine cross-resistance (MPXR) in these parasites and the current study aims to delineate the mechanism by which this occurs.; The TbAQP2 loci of isogenic pairs of drug-susceptible and MPXR strains of T. brucei subspecies were sequenced. Drug susceptibility profiles of trypanosome strains were correlated with expression of mutated TbAQP2 alleles. Pentamidine transport was studied in T. brucei subspecies expressing TbAQP2 variants.; All MPXR strains examined contained TbAQP2 deletions or rearrangements, regardless of whether the strains were originally adapted in vitro or in vivo to arsenicals or to pentamidine. The MPXR strains and AQP2 knockout strains had lost HAPT1 activity. Reintroduction of TbAQP2 in MPXR trypanosomes restored susceptibility to the drugs and reinstated HAPT1 activity, but did not change the activity of TbAT1/P2. Expression of TbAQP2 sensitized Leishmania mexicana promastigotes 40-fold to pentamidine and <1000-fold to melaminophenyl arsenicals and induced a high-affinity pentamidine transport activity indistinguishable from HAPT1 by Km and inhibitor profile. Grafting the TbAQP2 selectivity filter amino acid residues onto a chimeric allele of AQP2 and AQP3 partly restored susceptibility to pentamidine and an arsenical.; TbAQP2 mediates high-affinity uptake of pentamidine and melaminophenyl arsenicals in trypanosomes and TbAQP2 encodes the previously reported HAPT1 activity. This finding establishes TbAQP2 as an important drug transporter.

111 citations


Journal ArticleDOI
TL;DR: The care available for SCD in Nigeria is still suboptimal and there is an urgent need for concerted effort to tackle the problem, but to make a significant impact on the burden of the disease would require more focus at the primary care level.

105 citations


Journal ArticleDOI
TL;DR: ARIs are affected by socio-demographic and socio-cultural risk factors, which can be modified with simple strategies, and it is recommended that control program for ARIs should be multifaceted with a strong political will.
Abstract: Background: Acute respiratory tract infections (ARIs) constitute the major causes of mortality and morbidity among under‑five children of the developing world. The prevalence of ARIs is determined individually or collectively by a number of factors which may be prevalent in our environment. Aim: The present study is aimed to determine the risk factors that affect the prevalence of ARIs in under‑five children in Enugu. Subjects and Methods: A cross‑sectional study of 436 under‑five children diagnosed with ARI was carried out in three hospitals in Enugu. Participants were consecutively enrolled after being diagnosed as a case of ARI. Structured pro foma was used to collect sociodemographic characteristics, anthropometric data and risk profile. Data were analyzed using Epi info version 6.0 and significant probability value was 5%. Results: A total of 436 patients were enrolled for the study 224 males and 212 females M: F 1.06:1. The mean age of the population was 18.75(13.38) months and there were 31.6%(138/436) cases of pneumonia 6.9%(30/436) cases of bronchiolitis and 61.5%(268/436) cases of acute upper respiratory tract infections. Children less than 20 months accounted for 60.9% (84/138 cases) of pneumonia, 86.7% (26/30 cases) of bronchiolitis, and 64.5% (173/268 cases) of acute upper respiratory tract infections. Pneumonia was noted in about 75.7% (56/74) of inadequately nourished children compared to 22.6% (82/362) in adequately nourished children. Other risk factors identified in the study include inadequate breast feeding, poor immunization statues, attendance to daycare centers, large family size, poor parental educational statues, parental smoking, living in the urban area and use of biofuels. Conclusion: ARIs are affected by socio‑demographic and socio‑cultural risk factors, which can be modified with simple strategies. It is recommended that control program for ARIs should be multifaceted with a strong political will.

104 citations


Journal ArticleDOI
TL;DR: The future holds great prospects in the utilization of vesicular carriers, especially ethosomes, in overcoming peculiar problems of drug delivery as well as the future prospects and challenges of achieving enhanced drug delivery using ethosomes.
Abstract: Introduction: The application of vesicular carrier formulations has generated promise of overcoming some problems associated with drug delivery arising from not only the physicochemical properties of the drug but also those of the biological barriers, such as the membrane linings of various body tissues and the skin. This review article discusses the importance of various vesicular carriers, namely liposomes, niosomes, transfersomes and ethosomes in drug delivery with greater emphasis on ethosomes. Areas covered: The nature, mechanism of drug delivery, methods of preparation as well as characterization of vesicular carriers was discussed with a focus on ethosomes. An overview of their potential applications was provided with discussions on the future prospects and challenges of achieving enhanced drug delivery using ethosomes. Expert opinion: Vesicular carriers offer controlled and sustained drug release, improved permeability and protection of the encapsulated bioactives. Ethosomes offer more efficient a...

94 citations


Journal ArticleDOI
TL;DR: The results of the study suggest that Gouania longipetala is well tolerated in short term therapies, but may have long term toxic effects on the kidney and liver.

87 citations


Journal ArticleDOI
TL;DR: In this article, the authors measured the trigonometric parallax of an H2O maser source associated with the massive star-forming region NGC 6334I(North) with the VLBI Exploration of Radio Astrometry.
Abstract: We measured the trigonometric parallax of an H2O maser source associated with the massive star-forming region NGC 6334I(North), hereafter as NGC 6334I(N), with the VLBI Exploration of Radio Astrometry. The derived annual parallax is 0.789 ± 0.161 mas, corresponding to a distance of 1.26 kpc. Using the new distance, we recalculated the physical parameters (masses and luminosities) of the dust continuum cores in the region, and the revised parameters are only ~50% of their originally reported values. We also traced 23 relative proper motions of the H2O masers associated with SMA1 (central millimeter source in the region) between epochs, which exhibit an average amplitude of maser proper motion of ~2.03 mas yr–1 (~12.22 km s–1), tracing a bipolar outflow. The bipolar outflow structure extends through ~600 mas (~720 AU), with a dynamical timescale of ~295 yr. Using an expanding flow model, we derived the most plausible dynamical center of the outflow, pointing to SMA1b (1.3 cm and 7 mm continuum source) as the outflow driving source. Based on our results and other existing parallax results, we derive the pitch angles of the Sagittarius arm as 62 ± 54 along the Galactic longitude range of ~07 – ~401 assuming a perfect logarithmic spiral. We derived the peculiar motion of NGC 6334I(N) to be –4 ± 1 km s–1 toward the Galactic center, 8 ± 2 km s–1 in the direction of the Galactic rotation, and 25 ± 2 km s–1 toward the Galactic north pole.

75 citations


Journal ArticleDOI
TL;DR: Using an average femininity preference for each country, it was found men's facial femininity preferences correlated positively with the health of the nation, which explained 50.4% of the variation among countries.
Abstract: Both attractiveness judgements and mate preferences vary considerably cross-culturally. We investigated whether men's preference for femininity in women's faces varies between 28 countries with diverse health conditions by analysing responses of 1972 heterosexual participants. Although men in all countries preferred feminized over masculinized female faces, we found substantial differences between countries in the magnitude of men's preferences. Using an average femininity preference for each country, we found men's facial femininity preferences correlated positively with the health of the nation, which explained 50.4% of the variation among countries. The weakest preferences for femininity were found in Nepal and strongest in Japan. As high femininity in women is associated with lower success in competition for resources and lower dominance, it is possible that in harsher environments, men prefer cues to resource holding potential over high fecundity.

Journal ArticleDOI
TL;DR: The results reveal that African medicinal plants could represent a good starting point for the discovery of anticancer drugs, and are made available for research groups working on virtual screening.
Abstract: Naturally occurring anticancer compounds represent about half of the chemotherapeutic drugs which have been put in the market against cancer until date. Computer-based or in silico virtual screening methods are often used in lead/hit discovery protocols. In this study, the “drug-likeness” of ∼400 compounds from African medicinal plants that have shown in vitro and/or in vivo anticancer, cytotoxic, and antiproliferative activities has been explored. To verify potential binding to anticancer drug targets, the interactions between the compounds and 14 selected targets have been analyzed by in silico modeling. Docking and binding affinity calculations were carried out, in comparison with known anticancer agents comprising ∼1 500 published naturally occurring plant-based compounds from around the world. The results reveal that African medicinal plants could represent a good starting point for the discovery of anticancer drugs. The small data set generated (named AfroCancer) has been made available for research...

Journal ArticleDOI
TL;DR: In this article, the effects of various parameters such as water dilution, initial pH, heavy metals and nitrogen sources on digester performance were evaluated, and the results showed that the use of poultry droppings (PD) as nitrogen supplements encouraged biogas generation.

Journal ArticleDOI
TL;DR: In this paper, the authors analyzed the dominant mechanisms of slope failures and identified potential obstacles to landslide-hazard reduction at the Iva Valley area, Enugu, Nigeria and found that landslides mainly occur in the beginning of rainy season characterized by short duration, high intensity rainfall.
Abstract: This paper analyses the dominant mechanisms of slope failures and identifies potential obstacles to landslide-hazard reduction at the Iva Valley area, Enugu, Nigeria. The landscape is replete with landslide scars and gullies of varied sizes and the slope deposits comprise unconsolidated, friable sands inter-bedded with thin units of montmorillonitic claystone. Forty-three landslide events were identified in the study area with most being shallow, short run-out movements with slip-surface depth <2 m. The study found the landslides mainly occur in the beginning of rainy season characterized by short duration, high intensity rainfall. An integrated approach comprising field mapping, laboratory tests and numerical analyses reveals that the barren nature of the slopes prior to the outset of rainy season, high rainfall intensity, erosion, overgrazing, soil characteristics and the site’s unique lithologic sequence are the main causes of instability. Shearing tests under several conditions showed that the soils strongly strain-soften until low steady-state strength is achieved. A computer code, based on this strength reduction technique, used input parameters obtained from the field and laboratory studies to simulate a landslide with similar structure, travel distance and distribution area. It is noted that urbanization has gradually increased the vulnerability of the society’s poor to landslide hazards as they now erect unplanned residence (tents and blocks) on the slopes. This work is part of a regional study aimed at finding ways of protecting the vulnerable by generating data that could be used to build future landslide susceptibility map.

Journal ArticleDOI
TL;DR: Ex vivo study proves that ART permeates excised human epidermis, where the current formulation served as a reservoir to gradually control drug release over an extended period of time and may be a positive signal to hope for a topical delivery system of ART.

Journal ArticleDOI
TL;DR: Commonalities outweighed differences with respect to strategies to advance health-focused physical therapy as a clinical competency across regions and within target audiences.
Abstract: Based on indicators that emerged from The First Physical Therapy Summit on Global Health (2007), the Second Summit (2011) identified themes to inform a global physical therapy action plan to integrate health promotion into practice across the World Confederation for Physical Therapy (WCPT) regions. Working questions were: (1) how well is health promotion implemented within physical therapy practice; and (2) how might this be improved across five target audiences (i.e. physical therapist practitioners, educators, researchers, professional body representatives, and government liaisons/consultants). In structured facilitated sessions, Summit representatives (n = 32) discussed: (1) within WCPT regions, what is working and the challenges; and (2) across WCPT regions, what are potential directions using World CafeTM methodology. Commonalities outweighed differences with respect to strategies to advance health-focused physical therapy as a clinical competency across regions and within target audiences. P...

Journal ArticleDOI
TL;DR: In this paper, the US Army Research Laboratory-Broad Agency Announcement (BAA) (under Contract number W911NF-12-1-0588) was used for the development of a new sensor network.

Journal Article
TL;DR: In this paper, the authors examined household energy use and its determinants in Nigeria based on the 2004 Nigeria Living Standard Survey data obtained from the National Bureau of Statistics and found that most households in Nigeria use firewood as cooking fuel and kerosene for lighting.
Abstract: This study examined household energy use and its determinants in Nigeria based on the 2004 Nigeria Living Standard Survey data obtained from the National Bureau of Statistics. The study utilised descriptive statistics and multinomial logit models. Most households in Nigeria use firewood as cooking fuel and kerosene for lighting. This shows that most Nigerian households do not have adequate access to environmentally-friendly modern energy sources. Energy use in Nigeria supports fuel stacking rather than energy ladder hypothesis. Among the factors that significantly influence household energy use for cooking are educational levels of father and mother, per capita expenditure and household size. Adequate measures should be taken to ensure that most households in Nigeria have access to modern environmentally-friendly sources of energy. This will pave the way for sustainable development in the country. The results of this study should serve as an invaluable guide to the Nigerian government and policymakers. Keywords: Energy use; Multinomial logit; Poverty; Determinants; Nigeria. JEL Classifications: I32; Q40; R20


Journal ArticleDOI
TL;DR: The compliance rate of 65.9% for iron supplementation by pregnant mothers in Enugu can be improved by providing the drug free of charge in the short term and improvement in education and socioeconomic class of the populace in the long run.
Abstract: Background: Anemia in pregnancy is highly prevalent among antenatal clinic attendees in Enugu, Nigeria despite the practice of routine iron supplementation in pregnancy. The major problem with iron supplementation in pregnancy is compliance, and this may be a potential driver to the persistent high prevalence of anemia in this population. Objectives: To find out the compliance rate and determinants of compliance to iron supplementation among pregnant women in Enugu, southeastern Nigeria. Materials and Methods: This was a questionnaire-based cross-sectional study of eligible pregnant women receiving antenatal care at the University of Nigeria Teaching Hospital (UNTH), Ituku/Ozalla, Enugu, Nigeria between April 1, 2012 and January 31, 2013. Results: The knowledge of iron supplementation was 76.3% ( n = 302), however, the compliance rate was 65.9% ( n = 261). Tertiary level of education and high social class were factors significantly associated with compliance to iron supplementation after adjusting for other factors in the binary logistic regression analysis ( P Conclusion: The compliance rate of 65.9% for iron supplementation by pregnant mothers in Enugu can further be improved by providing the drug free of charge in the short term and improvement in education and socioeconomic class of the populace in the long run.

Journal ArticleDOI
TL;DR: The prevalence of DED among ophthalmic outpatients at UNTH, Enugu, is comparatively high and older age and illiteracy are predictors ofDED, suggesting there is need for high index of diagnostic suspicion to prevent sight-threatening complications of D ED.

Journal Article
TL;DR: From the analysis carried out by the researcher from the world Internet statistics (2012), it was found that out of the total population of 170,123,740 Nigeria, 5,860,240 numbers of people used Facebook as of 2012.
Abstract: Background of the StudySocial networking sites are fast becoming very popular means of both interpersonal and public communication in Nigeria. Social networking sites are modern interactive communication channels through which people connect to one another, share ideas, experiences, pictures, messages and information of interest. Boyd and Ellison (2007) define social networking sites as:''Web based services that allow individuals to construct a Public or semipublic profile within a bounded system (2) articulate a list of other users with whom they share a connection and (3)view and traverse their list of connections and those made by others within the system.(pp.78-100.)They are interactive networks which information and communication technology (ICTs) bequeath to the modern society through the instrumentality of the Internet and the telecommunication gadgets. The Internet makes it possible to expand the networks and to increase the possibilities for communicating with wider audiences on the globe. The interactive aura of the new media confers an unprecedented popularity on them. Also the ubiquity of the social networking sites within their short period of arrival is unparalleled in the annals of media industry. Awake (2011) buttresses this point by noting that ''social networking has become hugely popular. Similarly, it took 38 years for radio to reach 50 million users, 13 years for television to attract the same number and 4 years for the Internet to do so, but it took Facebook 12-month only to gain 200 million users. Social networking sites provide various interactive platforms based on the intentions of their founders. There are for instance, social, political, academic, businesses, sports, romantic and religious platform. In other words, the social networking site by their nature has the capabilities of educating, informing, entertaining and inflaming the audience. Onomo (2012) acknowledged this ability of the media by remarking that social networking sites has become ''a widespread tool for communication and exchange of ideas, helping individuals and organizations with just causes to reach a phenomenally vast audience that could hitherto not be reached by traditional media.''Thus, since inception, social networking sites like Facebook, twittser,2go, My Space, Skype etc. have mesmerized millions of users, many of whom have been made to use these sites as parts of their daily activities. Currently, there is a plethora of social networks with various features meant to suit the different interests of their followers. Some are accessed via computer alone while others can be used with mobile phones. The first identifiable social networking sites was launched in 1997, six degree. It allowed its users to create profiles, list their friends and in 1998, introduced the friends list where users had the freedom to search for old and new friends. This however was devoid of the provision for users to upload their profile pictures. Other social networking sites like classmates were founded to aid social interaction among their users but did not have many features like six degrees. Other social networking sites like Friendster and myspace created virtual community, which would help its members locate old and new ones, shape their personal profile via the Internet and socially idea or opinion under the sun. Two years later, Jack Dorsey Launched Twitter as an online blogging site, while the most recent 2go was founded in 2008 by Michael S. Egan. Therefore, just like radio and television, social networking has spread everywhere in Nigeria and are bound to be sprouting as the new media for are still obscure. In other words, from the analysis carried out by the researcher from the world Internet statistics (2012) it was found that out of the total population of 170,123,740 Nigeria, 5,860,240 numbers of people used Facebook as of 2012. Comparing Burundi and Chad with a similar population of 10,557259k and 199 75,648 respectively, the data shows that 37,040 and 36, 940 number of people respectively used Facebook as of 2012. …

Journal ArticleDOI
TL;DR: Prevalence of burnout and psychological distress is high among nurses in Nigeria, with high levels of burnouts identified in nurses working in Nigerian tertiary health institution.
Abstract: Background: The role of nurses in the health care delivery system cannot be overemphasized. Nurses are needed at all levels of healthcare and the profession requires a lot of dedication, time and energy with regards to patient management and service delivery. This time investment and dedication to duty is likely to lead to burnout and psychological distress among the nurses. Objective: This study assesses the prevalence of burnout and psychological distress among nurses working in Nigerian tertiary health institution. Method: The Maslach Burnout Inventory (MBI) and the General Health Questionnaire (GHQ-12) were used to assess 210 nurses working in this health institution for symptoms of burnout and psychological distress. Results: High levels of burnout were identified in 42.9% of the respondents in the area of emotional exhaustion, 47.6% in the area of depersonalization and 53.8% in the area of reduced personal accomplishment, while 44.1% scored positive in the GHQ-12 indicating presence of psychological distress. Conclusion: Prevalence of burnout and psychological distress is high among nurses. Keywords: Burnout, psychological distress, stress management African Health sciences Vol 14 No. 1 March 2014

Journal ArticleDOI
TL;DR: Moderate intensity aerobic exercise is an effective complementary therapy in lowering blood pressure and increasing CD4 cell count in PLWHA.
Abstract: Objective: Despite the significant positive effect of Highly Active Antiretroviral Therapy on physical and psychosocial well-being of people living with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) (PLWHA); decreased physical activity and its associated cardiovascular risk still pose some consequences for health and general well-being. This study investigated the effect of an 8 week aerobic exercise training on cardiovascular parameters and CD4 cell (T-cells) count of PLWHA. Materials and Methods: This randomized controlled trial recruited 30 age matched PLWHA who were randomly assigned into exercise group (EG) ( n = 15) and control group (CG) ( n = 15) respectively. The PLWHA were patients receiving treatment in President's Emergency Plan for AIDS relief at the HIV clinic of the University of Nigeria Teaching Hospital, Nigeria. The EG in addition to conventional therapy received moderate intensity continuous exercise training (60-79% of the maximum heart rate [max]) of between 45 and 60 min, 3 times/week for 8 weeks, while the CG received conventional therapy involving antiretroviral therapy and counseling only. Systolic blood pressure (SBP), diastolic blood pressure (DBP), maximum oxygen uptake (VO 2 max) and CD4 cell count were assessed at baseline (week 1) and week 8 respectively. Analysis of co-variance and Pearson correlation tests were used in data analysis. Results: Findings of the study revealed a significant effect (ANCOVA test) of moderate intensity continuous exercise training program on, SBP, DBP, VO 2 max and CD4 cell count at P Conclusion: Moderate intensity aerobic exercise is an effective complementary therapy in lowering blood pressure and increasing CD4 cell count in PLWHA.

Journal ArticleDOI
TL;DR: There is need for clinical trial on the benefits and adverse effects associated with the use of CAM to facilitate proof of efficacy and safety of the products.
Abstract: The use of complementary and alternative medicine (CAM) is now on the increase. Evidence from studies carried out globally has established that CAM use is very common and varies among populations. This study investigated patterns of CAM use, perceived benefits, and associated harm with CAM use among adults. A cross-sectional study was conducted in three local government areas of Enugu urban, Southeast Nigeria. An interviewer-administered questionnaire was used to collect data from all consenting adult participants aged between 18 and 65 years. Of the 732 participants interviewed, 62.8% were females while 37.2% were males. Majority (84.7%) of the participants had used CAM at one time or another. The most commonly used CAM product was the biological products, followed by spiritual therapy. The major route of administration for CAM products was oral and about 40% of the participants combined CAM with conventional medicine. Majority (78.6%) of CAM users benefited from CAM products after using them while a few complained of adverse reactions. As CAM is gaining widespread acceptance and use, there is need for clinical trial on the benefits and adverse effects associated with the use of CAM to facilitate proof of efficacy and safety of the products.

Journal ArticleDOI
TL;DR: Anatomy Adventure, a board game on anatomy was designed to reduce some of these pressures, emphasize student centered and collaborative learning styles, and add fun to the process of learning while promoting understanding and retention of the subject.
Abstract: Certain negative factors such as fear, loss of concentration and interest in the course, lack of confidence, and undue stress have been associated with the study of anatomy. These are factors most often provoked by the unusually large curriculum, nature of the course, and the psychosocial impact of dissection. As a palliative measure, Anatomy Adventure, a board game on anatomy was designed to reduce some of these pressures, emphasize student centered and collaborative learning styles, and add fun to the process of learning while promoting understanding and retention of the subject. To assess these objectives, 95 out of over 150 medical and dental students who expressed willingness to be part of the study were recruited and divided into a Game group and a Non-game group. A pretest written examination was given to both groups, participants in the Game group were allowed to play the game for ten days, after which a post-test examination was also given. A 20-item questionnaire rated on a three-point scale to access student's perception of the game was given to the game group. The post-test scores of the game group were significantly higher (P < 0.05) than those of the non-game counterparts. Also the post-test score of the game based group was significantly better (P < 0.05) than their pretest. The students in their feedback noted in very high proportions that the game was interesting, highly informative, encouraged team work, improved their attitude, and perception to gross anatomy. Anat Sci Educ 7: 153–160. © 2013 American Association of Anatomists.

Journal ArticleDOI
TL;DR: Diabetes self-care knowledge was generally high among the population studied, and educational status, monthly income, duration of diabetes and negative attitude to disease condition predicted knowledge level.
Abstract: Objective: To assess the knowledge of self-care practices, as well as factors responsible for such knowledge among type 2 diabetes patients in two states of

Journal ArticleDOI
TL;DR: Based on the merits of nature based medicines, the authors advocate the use of standardized crude forms of some of the natural drugs, including flavonoids, glycosides, terpens, polysaccharides and polypeptides.
Abstract: Natural products have played and continue to play an invaluable role in the treatment of various diseases and in drug discovery processes. It has remained a source of new compounds with diversified structural arrangements possessing interesting biological activities for various disease treatments. Drugs from natural products are usually considered to be safer, cheaper, easily available and sometimes more efficacious than purely synthetic ones. In recent years, scientists have been in search for safer and more potent drugs from natural sources particularly from medicinal plants. Diabetes is one of the chronic disorders which are associated with high mortality risk. The existing drugs have been identified with one or more adverse effects. In the present review, literature was surveyed to highlight the merits of natural products with regard to their role in diabetic management. Notwithstanding the seemingly decline in the natural product approach to drug discovery in favor of modern approaches such as combinatorial chemistry, literature survey has shown that a lot of research effort is still being directed to natural product in search for new antidiabetic agents. Several antidiabetic phytoconstituents have been isolated from medicinal plants and these were of chemically diversified nature which includes flavonoids, glycosides, terpens, polysaccharides and polypeptides. Based on the merits of nature based medicines, the authors advocate the use of standardized crude forms of some of the natural drugs. Further researches geared towards exploiting the vast array of natural products in our environment and development of the isolated compounds to clinically useful drugs for diabetes management is advocated.

Journal ArticleDOI
TL;DR: In this paper, the authors present a survey of performance assessment methods based on energy, entropy and exergy analyses for stratified thermal energy storage systems (STESS) and highlight entropy generation ratios, which are based on second law considerations, as effective in quantifying the improvements in STESS performances that result from the presence of stratification unlike energy-based measures.
Abstract: The presence of stratification is well known to improve the performance of stratified thermal energy storage systems (STESS). The major energy and exergy methods for modeling and assessing the performance of STESS are reviewed in this presentation. Current analytical and numerical methods for modeling STESS are surveyed, with their strengths and weaknesses. An extensive survey of performance assessment methods based on energy, entropy and exergy analyses is also presented. This survey highlights entropy generation ratios, which are based on second law considerations, as effective in quantifying the improvements in STESS performances that result from the presence of stratification unlike energy-based measures. The entropy generation number, Ns is suggested as an effective tool for future performance studies on STESS.

Journal ArticleDOI
TL;DR: The status of Aquaculture in Nigeria, its problems and development prospects, different fish species that can adequately thrive in Nigerian pond and its preparation, and some first-rate management practices that can boost aquaculture production in Nigeria are reviewed.
Abstract: Fish is an important source of food, income, employment, and recreation for people around the world and it is a very important source of animal protein for both man and livestock in developed and developing countries. In Nigeria, the current demand for fish is about four times the level of local production. Humans consume approximately 80 percent of the catch as food. The remaining 20 percent goes into the manufacturing of products such as fish oil, fertilizers, and animal food. Fisheries and aquaculture are integral parts of agriculture which were found to have the capacity to increase the country’s GDP (Gross Domestic Product) and can solve the unemployment problem for our teeming youths if adequately managed. Therefore, this paper reviewed the status of Aquaculture in Nigeria, its problems and development prospects, different fish species that can adequately thrive in Nigerian pond and its preparation, and finally showed some first-rate management practices that can boost aquaculture production in Nigeria