University of North Carolina at Charlotte

About: University of North Carolina at Charlotte is a education organization based out in Charlotte, North Carolina, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 8772 authors who have published 22239 publications receiving 562529 citations. The organization is also known as: UNC Charlotte & UNCC.

Facts versus `Feelings': How Rational Is the Decision to Become an Organ Donor?

Abstract: Researchers are already aware that decision making about health issues is not necessarily driven by rational or cognitive-based decision-making processes. This appears to be especially true for the decision to donate organs. Although hints about what is actually driving the decision-making process are scattered throughout the literature, noncognitive factors have not been tested systematically. Structural equation modeling of data gathered from 4426 participants at six different geographic locations in the United States demonstrates that cognitive-based factors (such as knowledge about donation) are less influential on the decision to donate than noncognitive variables such as the desire to maintain bodily integrity, worries that signing a donor card might 'jinx' a person, and medical mistrust.

Nitric oxide as a regulator of embryonic development

Abstract: The role of nitric oxide (NO) in activation of cGMP is well established. It has been proposed that the ratio of cAMP to cGMP may be important in the regulation of preimplantation embryonic growth and differentiation. Therefore, we determined the ability of murine preimplantation embryos to produce NO. In addition, NO as an endogenous smooth muscle relaxant and vasodilator is a candidate for involvement in embryo implantation because this process requires increased vascular permeability and uterine quiescence at the sites of blastocyst apposition. Nitrite assays, an indirect measure of NO production, indicate that preimplantation murine embryos produce NO. This production was reversibly inhibited by culture of embryos in medium containing a nonspecific NO synthase (NOS) inhibitor (NG-nitro-L-arginine). Additionally, inhibition of normal development was observed in embryos cultured with NOS inhibitor. NO levels increased in culture medium when ovariectomized progesterone-treated animals were exposed to estrogen for 1 h in utero. Such hormonal treatment induces implantation. These data indicate that NO levels are regulated by estrogen and may be important in regulation of implantation. In addition, these data demonstrate for the first time that NO production appears to be required for normal embryonic development.

Ankle ligament healing after an acute ankle sprain: an evidence-based approach.

Abstract: Objective: To perform a systematic review to determine the healing time of the lateral ankle ligaments after an acute ankle sprain. Data Sources: We identified English-language research studies from 1964 to 2007 by searching MEDLINE, Physiotherapy Evidence Database (PEDro), SportDiscus, and CINAHL using the terms ankle sprain, ankle rehabilitation, ankle injury, ligament healing, and immobilization. Study Selection: We selected studies that described randomized, controlled clinical trials measuring ligament laxity either objectively or subjectively immediately after injury and at least 1 more time after injury. Data Extraction: Two reviewers independently scored the 7 studies that met the inclusion criteria. Because of differences in study designs, a meta-analysis could not be performed. Effect sizes and confidence intervals could be calculated only for 1 study. The percentages of subjective and objective instability were calculated for the remaining studies. Data Synthesis: Ankle laxity improved...

Staying Back and Dropping Out: The Relationship Between Grade Retention and School Dropout

Abstract: Students who repeat a grade prior to high school have a higher risk of dropping out of high school than do students who are continuously promoted. This study tested whether standard theories of dro...

Resonant tunneling via microcrystalline-silicon quantum confinement.

Abstract: Observation experimentale de l'effet tunnel resonnant impliquant les etats-quantiques discrets dans Si microcristallin (μc-Si) avec des barrieres de SiO 2 amorphe (a-SiO 2 ). Les faibles densites de pieges interfaciales, et la hauteur de barriere elevee entre Si et a-SiO 2 , permettent l'observation de plusieurs aspects dans la physique du confinement quantique. Meme pour le confinement quantique extreme a la faible polarisation, appliquee a la structure Al/a-SiO 2 /μc-Si/a-SiO 2 /c-Si, les effets de l'accumulation de la charge quantifiee dominent l'espacement plus large des niveaux d'energie de la boite quantique. Aux fortes polarisations, on observe une transition d'un systeme confine tridimensionnellement vers un systeme confine bidimensionnellement