Institution
University of North Carolina at Charlotte
Education•Charlotte, North Carolina, United States•
About: University of North Carolina at Charlotte is a education organization based out in Charlotte, North Carolina, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 8772 authors who have published 22239 publications receiving 562529 citations. The organization is also known as: UNC Charlotte & UNCC.
Topics: Population, Poison control, Health care, Visualization, Mental health
Papers published on a yearly basis
Papers
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TL;DR: Routine HRQL assessment, even with description of results, is insufficient to improve patient HRQL and satisfaction, and it is suggested that positive effects may require supplementing assessment results with specific suggestions for clinical management changes.
Abstract: The potential benefits of health-related quality of life (HRQL) assessment in oncology clinical practice include better detection of problems, enhanced disease and treatment monitoring and improved care. However, few empirical studies have investigated the effects of incorporating such assessments into routine clinical care. Recent randomized studies have reported improved detection of and communication about patients' concerns, but few have found effects on patient HRQL or satisfaction. This study examined whether offering interpretive assistance of HRQL results would improve these patient outcomes. Two hundred and thirteen participants with metastatic breast, lung or colorectal cancer were randomly assigned to one of three conditions: usual care; HRQL assessment or HRQL assessment followed by a structured interview and discussion. Interviews about patients' assessment responses were conducted by a research nurse, who then presented HRQL information to the treating nurse. HRQL and treatment satisfaction outcomes were assessed at 3 and 6 months. No significant differences were found between study conditions in HRQL or satisfaction. Results suggest that routine HRQL assessment, even with description of results, is insufficient to improve patient HRQL and satisfaction. It is suggested that positive effects may require supplementing assessment results with specific suggestions for clinical management changes.
133 citations
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TL;DR: In this article, the authors argue that K-12 schools are integral to augmenting and diversifying the science, technology, engineering, and mathematics (STEM) workforce and that they can inspire and reinforce students.
Abstract: Background/ContextSchools are integral to augmenting and diversifying the science, technology, engineering, and mathematics (STEM) workforce This is because K–12 schools can inspire and reinforce
133 citations
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TL;DR: In this paper, a newsboy problem with multiple e discounts is formulated and solved with the objectives of maximizing the expected profit and maximizing the probability of achieving a target profit, and it is shown that multiple discounts, when possible, provide higher expected profit than using a single discount.
133 citations
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TL;DR: A review of the experimental literature on alcohol and interpersonal aggression is presented in this article, where the dominant experimental paradigms are reviewed and a synthesis of findings from seven published meta-analytic studies is presented.
133 citations
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TL;DR: These studies are the first to demonstrate induced IL-12p75 expression by osteoblasts and suggest a previously unrecognized role for osteoblast in initiating immune responses after S. aureus infection.
Abstract: Staphylococcus aureus is the principal causative agent of the inflammatory bone disease osteomyelitis. Unfortunately, the pathogenesis of this often chronic infection is poorly understood and is complicated by the recent observation that bone-forming osteoblasts can harbor S. aureus. Such an infection presents a significant challenge for the host immune response, because osteoblasts are not known to initiate protective cell-mediated immune responses. Cultured mouse and human osteoblasts infected with S. aureus were found to express high levels of interleukin (IL)-6 and IL-12p75, on the basis of complementary investigations demonstrating both S. aureus-induced up-regulation of expression of IL-6 and IL-12p40 mRNA and secretion of IL-6 and IL-12p75 by these cells. Additionally, a quantitative bioassay demonstrated that IL-12p75 secreted after infection was biologically active. These studies are the first to demonstrate induced IL-12p75 expression by osteoblasts and suggest a previously unrecognized role for osteoblasts in initiating immune responses after S. aureus infection.
133 citations
Authors
Showing all 8936 results
Name | H-index | Papers | Citations |
---|---|---|---|
Chao Zhang | 127 | 3119 | 84711 |
E. Magnus Ohman | 124 | 622 | 68976 |
Staffan Kjelleberg | 114 | 425 | 44414 |
Kenneth L. Davis | 113 | 622 | 61120 |
David Wilson | 102 | 757 | 49388 |
Michael Bauer | 100 | 1052 | 56841 |
David A. B. Miller | 96 | 702 | 38717 |
Ashutosh Chilkoti | 95 | 414 | 32241 |
Chi-Wang Shu | 93 | 529 | 56205 |
Gang Li | 93 | 486 | 68181 |
Tiefu Zhao | 90 | 593 | 36856 |
Juan Carlos García-Pagán | 90 | 348 | 25573 |
Denise C. Park | 88 | 267 | 33158 |
Santosh Kumar | 80 | 1196 | 29391 |
Chen Chen | 76 | 853 | 24974 |