University of North Carolina at Charlotte

About: University of North Carolina at Charlotte is a education organization based out in Charlotte, North Carolina, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 8772 authors who have published 22239 publications receiving 562529 citations. The organization is also known as: UNC Charlotte & UNCC.

MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

Abstract: MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

The value of positive psychology for health psychology: progress and pitfalls in examining the relation of positive phenomena to health.

Abstract: The growth of the "positive psychology" movement reflects increased scientific and lay interest in the relation of positive phenomena to mental and physical health and the corresponding potential for interventions that promote positive feelings, thoughts, and experiences to improve health and well-being. In this article, we (1) consider research on optimism, sense of coherence, and posttraumatic growth that predates the contemporary emphasis on positive psychology, but has clear and increasingly well-supported connections to health psychology, (2) examine several potential mechanisms through which such positive phenomena may influence the etiology, progression, and management of illness, (3) identify four pervasive but misleading assumptions about positive phenomena that may limit both scientific research and practical application, and (4) caution against serious pitfalls of popular views of positive thinking, such as its promotion as a cure for cancer and other diseases. We conclude with recommendations for the balanced scientific investigation and application of positive phenomena.

Formation of nonculturable Vibrio vulnificus cells and its relationship to the starvation state.

Abstract: Entry into the viable but nonculturable state by the human bacterial pathogen Vibrio vulnificus in artificial seawater microcosms was studied. In contrast to the long-term culturability exhibited by cells incubated under these starvation conditions at room temperature, cells exposed to a temperature downshift to 5 degrees C exhibited an immediate decrease in culturability. Cells incubated at low temperature exhibited a morphological change from rods to cocci but demonstrated no reductive division. Of 10 factors studied which might affect the nonculturable response in V. vulnificus, only the physiological age of the cells was found to significantly affect the rate at which cells became nonculturable. The nonculturable response appears to be related to the starvation response, as prestarvation at room temperature for 24 h was found to eliminate the nonculturable response of cells subsequently incubated at 5 degrees C. This observation suggests that the synthesis of starvation proteins may repress the viable but nonculturable program displayed during low-temperature incubation. The possible ecological significance of these findings is discussed.