Institution
University of North Carolina at Greensboro
Education•Greensboro, North Carolina, United States•
About: University of North Carolina at Greensboro is a education organization based out in Greensboro, North Carolina, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 5481 authors who have published 13715 publications receiving 456239 citations. The organization is also known as: UNCG & UNC Greensboro.
Papers published on a yearly basis
Papers
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TL;DR: In this article, panel data methods are used to investigate how deaths from coronary heart disease (CHD) in the United States vary with macroeconomic conditions, showing that CHD mortality increases rapidly when the economy strengthens but returns to or near its baseline level within five years for most groups.
Abstract: Panel data methods are used to investigate how deaths from coronary heart disease (CHD) in the United States vary with macroeconomic conditions. A one-percentage-point reduction in unemployment is predicted to raise CHD mortality by 0.75%, corresponding to almost 3,900 additional fatalities. The increase in relative risk is similar across age groups, implying that senior citizens account for most of the extra deaths. Direct evidence is obtained of a role for decreases in medical interventions treating coronary problems. CHD mortality increases rapidly when the economy strengthens but returns to or near its baseline level within five years for most groups.
276 citations
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TL;DR: In this paper, a review of research conducted in the past decade on families with young chidren concentrated on five broad topics: the transition to parenthood, the importance of maternal sensitivity for children's attachment security and subsequent adjustment and social competence, the effectiveness of particular parenting styles and practices, interparental, familial, and broader societal factors influencing parenting behaviors and child adjustment, and the impact of family structure and household composition on children's well-being.
Abstract: Research conducted in the past decade on families with young chidren concentrated on 5 broad topics: (a) the transition to parenthood,' (b) the importance of maternal sensitivity for children's attachment security and subsequent adjustment and social competence; (c) the effectiveness of particular parenting styles and practices; (d) interparental, familial, and broader societal factors influencing parenting behaviors and child adjustment; and (e) the impact of family structure and household composition on children's well-being. Our review documents substantial diversity in family structures, parenting arrangements, and childrearing values and practices both within and across ethnic and racial groups. Collectively, the evidence suggests that in most families with young children, parents and children seem to be doing well. We conclude that substantial work is required to expand the study of families with young children beyond mother-child dyads in White, middle-class, two-parent, first-marriage families.
276 citations
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TL;DR: The data suggest that sily marin- and silymarin-derived compounds may influence HCV disease course in some patients.
Abstract: Silymarin, also known as milk thistle extract, inhibits hepatitis C virus (HCV) infection and also displays antioxidant, anti-inflammatory, and immunomodulatory actions that contribute to its hepatoprotective effects. In the current study, we evaluated the hepatoprotective actions of the seven major flavonolignans and one flavonoid that comprise silymarin. Activities tested included inhibition of: HCV cell culture infection, NS5B polymerase activity, TNF-α-induced NF-κB transcription, virus-induced oxidative stress, and T-cell proliferation. All compounds were well tolerated by Huh7 human hepatoma cells up to 80 μM, except for isosilybin B, which was toxic to cells above 10 μM. Select compounds had stronger hepatoprotective functions than silymarin in all assays tested except in T cell proliferation. Pure compounds inhibited JFH-1 NS5B polymerase but only at concentrations above 300 μM. Silymarin suppressed TNF-α activation of NF-κB dependent transcription, which involved partial inhibition of IκB and RelA/p65 serine phosphorylation, and p50 and p65 nuclear translocation, without affecting binding of p50 and p65 to DNA. All compounds blocked JFH-1 virus-induced oxidative stress, including compounds that lacked antiviral activity. The most potent compounds across multiple assays were taxifolin, isosilybin A, silybin A, silybin B, and silibinin, a mixture of silybin A and silybin B. The data suggest that silymarin- and silymarin-derived compounds may influence HCV disease course in some patients. Studies where standardized silymarin is dosed to identify specific clinical endpoints are urgently needed.
275 citations
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TL;DR: It is indicated that people have only moderate insight into their abilities but also underscore the contextual factors that enable accurate self-perception of ability.
Abstract: Having insight into one’s abilities is essential, yet it remains unclear whether people generally perceive their skills accurately or inaccurately. In the present analysis, we examined the overall correspondence between self-evaluations of ability (e.g., academic ability, intelligence, language competence, medical skills, sports ability, and vocational skills) and objective performance measures (e.g., standardized test scores, grades, and supervisor evaluations) across 22 meta-analyses, in addition to considering factors that moderate this relationship. Although individual meta-analytic effects ranged from .09 to .63, the mean correlation between ability self-evaluations and performance outcomes across meta-analyses was moderate (M = .29, SD = .11). Further, the relation was stronger when self-evaluations were specific to a given domain rather than broad and when performance tasks were objective, familiar, or low in complexity. Taken together, these findings indicate that people have only moderate insight into their abilities but also underscore the contextual factors that enable accurate self-perception of ability.
271 citations
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TL;DR: In this article, a preliminary investigation using functional magnetic resonance imaging (fMRI) to examine neural responses to positive, negative, and neutral pictures in unmedicated major depressive disorder patients (N = 22) versus controls (n = 14).
271 citations
Authors
Showing all 5571 results
Name | H-index | Papers | Citations |
---|---|---|---|
Douglas E. Soltis | 127 | 612 | 67161 |
John C. Wingfield | 122 | 509 | 52291 |
Laurence Steinberg | 115 | 403 | 70047 |
Patrick Y. Wen | 109 | 838 | 52845 |
Mark T. Greenberg | 107 | 529 | 49878 |
Steven C. Hayes | 106 | 450 | 51556 |
Edward McAuley | 105 | 451 | 45948 |
Roberto Cabeza | 94 | 252 | 36726 |
K. Ranga Rama Krishnan | 90 | 299 | 26112 |
Barry J. Zimmerman | 88 | 177 | 56011 |
Michael K. Reiter | 84 | 380 | 30267 |
Steven R. Feldman | 83 | 1227 | 37609 |
Charles E. Schroeder | 82 | 234 | 26466 |
Dale H. Schunk | 81 | 162 | 45909 |
Kim D. Janda | 79 | 731 | 26602 |