University of North Carolina at Greensboro

About: University of North Carolina at Greensboro is a education organization based out in Greensboro, North Carolina, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 5481 authors who have published 13715 publications receiving 456239 citations. The organization is also known as: UNCG & UNC Greensboro.

Assessing population genetic structure and variability with RAPD data: Application to Vaccinium macrocarpon (American Cranberry)

Abstract: A method for estimating and comparing population genetic variation using random amplified polymorphic DNA (RAPD) profiling is presented. An analysis of molecular variance (AMOVA) is extended to accomodate phenotypic molecular data in diploid populations in Hardy-Weinberg equilibrium or with an assumed degree of selfing. We present a two step strategy: 1) Estimate RAPD site frequencies without preliminary assumptions on the unknown population structure, then perform significance testing for population substructuring. 2) If population structure is evident from the first step, use this data to calculate better estimates for RAPD site frequencies and sub-population variance components. A nonparametric test for the homogeneity of molecular variance (HOMOVA) is also presented. This test was designed to statistically test for differences in intrapopulational molecular variances (heteroscedasticity among populations). These theoretical developments are applied to a RAPD data set in Vaccinium macrocarpon (American cranberry) using small sample sizes, where a gradient of molecular diversity is found between central and marginal populations. The AMOVA and HOMOVA methods provide flexible population analysis tools when using data from RAPD or other DNA methods that provide many polymorphic markers with or without direct allelic data.

Ethnic socialization of African American children: Implications for parenting, identity development, and academic achievement

Abstract: This research explores ethnic socialization among middle-income African American parents and their children who attend predominantly white schools. Descriptive data regarding parents' and children's reports of ethnic socialization practices were obtained. Additionally, the relationship between ethnic socialization, ethnic identity, and academic achievement was assessed through correlational and predictive statistics. Correlation analyses indicated that children's reports of ethnic socialization were significantly related to the encounter stage of ethnic identity. Surprisingly, the child's report of ethnic socialization was predictive of lower classroom grades. Findings are discussed in terms of their implications for ethnic socialization and identity development among African American children.

Manganese and its Role in Parkinson's disease: from Transport to Neuropathology.

Abstract: The purpose of this review is to highlight recent advances in the neuropathology associated with Mn exposures. We commence with a discussion on occupational manganism and clinical aspects of the disorder. This is followed by novel considerations on Mn transport (see also chapter by Yokel, this volume), advancing new hypotheses on the involvement of several transporters in Mn entry into the brain. This is followed by a brief description of the effects of Mn on neurotransmitter systems that are putative modulators of dopamine (DA) biology (the primary target of Mn neurotoxicity), as well as its effects on mitochondrial dysfunction and disruption of cellular energy metabolism. Next, we discuss inflammatory activation of glia in neuronal injury and how disruption of synaptic transmission and glial-neuronal communication may serve as underlying mechanisms of Mn-induced neurodegeneration commensurate with the cross-talk between glia and neurons. We conclude with a discussion on therapeutic aspects of Mn exposure. Emphasis is directed at treatment modalities and the utility of chelators in attenuating the neurodegenerative sequelae of exposure to Mn. For additional reading on several topics inherent to this review as well as others, the reader may wish to consult Aschner and Dorman (Toxicological Review 25:147–154, 2007) and Bowman et al. (Metals and neurodegeneration, 2009).

Examining Female Entrepreneurs' Management Style: An Application of a Relational Frame

Abstract: This paper reports the results of a qualitative analysis of female entrepreneurs' accounts of their role in their organizations using Relational Theory as the analytical frame. Content analysis of focus group comments indicated that the women used a relational approach in working with employees and clients. Relational skills included preserving, mutual empowering, achieving, and creating team. Findings demonstrate that Relational Theory is a useful frame for identifying and explicating women entrepreneurs' interactive style in their own businesses. Implications and future directions for research are discussed.

Impact of Exposure to Violence in School on Child and Adolescent Mental Health and Behavior.

Abstract: Exposure to violence at school remains a significant problem for children and adolescents. This study examined the relationship between exposure to violence at school and child reports of psychological trauma symptoms and violent behavior. The sample consisted of children in grades 3 through 12 in 17 public schools from two different states. Rates of witnessing violence ranged from 56% of elementary-school students witnessing someone else being beaten up to 87% of students witnessing someone else being hit, slapped, or punched at school in the past year. Nearly half (44 %) of middle-school youth were threatened at school. After accounting for demographic effects, witnessing violence at school accounted for more variance than being victimized by violence at school in predicting both psychological trauma symptoms and violent behavior. Students who were exposed to high levels of violence at school also were significantly more likely to experience clinical levels of trauma symptoms than students who were exposed to low levels of violence at school. The association between exposure to violence at school and child well being are discussed.