Institution
University of North Carolina at Greensboro
Education•Greensboro, North Carolina, United States•
About: University of North Carolina at Greensboro is a education organization based out in Greensboro, North Carolina, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 5481 authors who have published 13715 publications receiving 456239 citations. The organization is also known as: UNCG & UNC Greensboro.
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TL;DR: Investigation of the contexts provided by formal and informal institutions affect the perceptions of privacy and security issues in the cloud investigates how contradictions generated at various levels by the technology, the formation of dense networks and relationships and the changing power dynamics have triggered institutional changes.
178 citations
TL;DR: A novel posttranslational mechanism of copper homeostasis in vivo consistent with the proposed function of the Wilson's disease protein in holoceruloplasmin biosynthesis and biliary copper excretion is revealed and is of relevance to the broad clinical heterogeneity observed in this disease.
Abstract: Wilson’s disease is an inherited disorder of copper metabolism characterized by hepatic cirrhosis and neuronal degeneration. In this current study, a polyclonal antiserum specific for the Wilson’s ...
178 citations
University of California, Irvine1, Birkbeck, University of London2, University of Washington3, University of Arkansas at Little Rock4, University of Pittsburgh5, University of North Carolina at Chapel Hill6, University of Arkansas for Medical Sciences7, National Institutes of Health8, Temple University9, University of Texas at Austin10, Michigan State University11, RTI International12, Wellesley College13, Harvard University14, University of North Carolina at Greensboro15, University of Texas at Dallas16, Georgetown University17, University of Virginia18, University of Maryland, College Park19, University of Wisconsin-Madison20
178 citations
TL;DR: The first draft of the honey bee genome sequence and improved genetic maps are utilized to analyze a genome displaying 10 times higher levels of recombination (19 cM/Mb) than previously analyzed genomes of higher eukaryotes as mentioned in this paper.
Abstract: The first draft of the honey bee genome sequence and improved genetic maps are utilized to analyze a genome displaying 10 times higher levels of recombination (19 cM/Mb) than previously analyzed genomes of higher eukaryotes. The exceptionally high recombination rate is distributed genome-wide, but varies by two orders of magnitude. Analysis of chromosome, sequence, and gene parameters with respect to recombination showed that local recombination rate is associated with distance to the telomere, GC content, and the number of simple repeats as described for low-recombining genomes. Recombination rate does not decrease with chromosome size. On average 5.7 recombination events per chromosome pair per meiosis are found in the honey bee genome. This contrasts with a wide range of taxa that have a uniform recombination frequency of about 1.6 per chromosome pair. The excess of recombination activity does not support a mechanistic role of recombination in stabilizing pairs of homologous chromosome during chromosome pairing. Recombination rate is associated with gene size, suggesting that introns are larger in regions of low recombination and may improve the efficacy of selection in these regions. Very few transposons and no retrotransposons are present in the high-recombining genome. We propose evolutionary explanations for the exceptionally high genome-wide recombination rate.
177 citations
TL;DR: The findings support the construct validity of a multidimensional model of schizotypy and the use of psychometric inventories to assess these dimensions, which were differentially related to psychopathology, personality, and social impairment.
177 citations
Authors
Showing all 5571 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Douglas E. Soltis | 127 | 612 | 67161 |
| John C. Wingfield | 122 | 509 | 52291 |
| Laurence Steinberg | 115 | 403 | 70047 |
| Patrick Y. Wen | 109 | 838 | 52845 |
| Mark T. Greenberg | 107 | 529 | 49878 |
| Steven C. Hayes | 106 | 450 | 51556 |
| Edward McAuley | 105 | 451 | 45948 |
| Roberto Cabeza | 94 | 252 | 36726 |
| K. Ranga Rama Krishnan | 90 | 299 | 26112 |
| Barry J. Zimmerman | 88 | 177 | 56011 |
| Michael K. Reiter | 84 | 380 | 30267 |
| Steven R. Feldman | 83 | 1227 | 37609 |
| Charles E. Schroeder | 82 | 234 | 26466 |
| Dale H. Schunk | 81 | 162 | 45909 |
| Kim D. Janda | 79 | 731 | 26602 |