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Institution

University of North Texas

EducationDenton, Texas, United States
About: University of North Texas is a education organization based out in Denton, Texas, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 11866 authors who have published 26984 publications receiving 705376 citations. The organization is also known as: Fight, North Texas & UNT.


Papers
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Journal ArticleDOI
28 Feb 2014-Mbio
TL;DR: A general model in which faculty and teaching assistants from diverse academic institutions are trained to teach a research course for first-year undergraduate students focused on bacteriophage discovery and genomics is developed, showing that this alliance-sourced model not only substantially advances the field of phage genomics but also stimulates students’ interest in science, positively influences academic achievement, and enhances persistence inScience, technology, engineering, and mathematics (STEM) disciplines.
Abstract: Engaging large numbers of undergraduates in authentic scientific discovery is desirable but difficult to achieve. We have developed a general model in which faculty and teaching assistants from diverse academic institutions are trained to teach a research course for first-year undergraduate students focused on bacteriophage discovery and genomics. The course is situated within a broader scientific context aimed at understanding viral diversity, such that faculty and students are collaborators with established researchers in the field. The Howard Hughes Medical Institute (HHMI) Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science (SEA-PHAGES) course has been widely implemented and has been taken by over 4,800 students at 73 institutions. We show here that this alliance-sourced model not only substantially advances the field of phage genomics but also stimulates students’ interest in science, positively influences academic achievement, and enhances persistence in science, technology, engineering, and mathematics (STEM) disciplines. Broad application of this model by integrating other research areas with large numbers of early-career undergraduate students has the potential to be transformative in science education and research training. IMPORTANCE Engagement of undergraduate students in scientific research at early stages in their careers presents an opportunity to excite students about science, technology, engineering, and mathematics (STEM) disciplines and promote continued interests in these areas. Many excellent course-based undergraduate research experiences have been developed, but scaling these to a broader impact with larger numbers of students is challenging. The Howard Hughes Medical Institute (HHMI) Science Education Alliance Phage Hunting Advancing Genomics and Evolutionary Science (SEA-PHAGES) program takes advantage of the huge size and diversity of the bacteriophage population to engage students in discovery of new viruses, genome annotation, and comparative genomics, with strong impacts on bacteriophage research, increased persistence in STEM fields, and student self-identification with learning gains, motivation, attitude, and career aspirations.

396 citations

Journal ArticleDOI
TL;DR: The authors explored the effect of exposure to entrepreneurial role models on entrepreneurial career intention, and found that role models have a significant and positive impact on intention, that gender moderated the effects, and that self-efficacy mediated it.
Abstract: This paper addresses the effects of role models and self-efficacy on forming career intentions, and whether the effects vary by gender and process. Focusing on entrepreneurship as a career choice, we explored (a) the effect of exposure to entrepreneurial role models on entrepreneurial career intention; (b) the difference in effects between men and women; and (c) the mediating functionality of self-efficacy. Results indicate that role models have a significant and positive impact on intention, that gender moderated the effects, and that self-efficacy mediated it. A moderated mediation relationship was observed such that, for women, role models had stronger influence on self-efficacy, which, in turn, influenced entrepreneurial career intention. Results are discussed in terms of implications for theory and practice.

395 citations

Journal ArticleDOI
TL;DR: The proposed algorithm integrates a statistical simulated annealing algorithm with the traditional iterative code selection method and is demonstrated to be effective for the design of polyphase signals used in ONRS.
Abstract: Orthogonal netted radar systems (ONRS) can fundamentally improve radar performance by using a group of specially designed orthogonal signals. A novel hybrid algorithm is proposed to numerically optimize such orthogonal polyphase code sets. The proposed algorithm integrates a statistical simulated annealing algorithm with the traditional iterative code selection method and is demonstrated to be effective for the design of polyphase signals used in ONRS. Some of the design results are presented and discussed. The effect of Doppler frequency shift on the performance of the designed signals is also investigated.

395 citations

Journal ArticleDOI
TL;DR: Adding very small amounts of zinc to magnesium alloys containing rare earth elements dramatically improves their creep life, and it is shown that this is due to stiff covalent bonding of zinc and rare earth Elements such as neodymium.
Abstract: Several recent papers report spectacular, and unexpected, order of magnitude improvement in creep life of alloys upon adding small amounts of elements like zinc. This microalloying effect raises fundamental questions regarding creep deformation mechanisms. Here, using atomic-scale characterization and first principles calculations, we attribute the 600% increase in creep life in a prototypical Mg–rare earth (RE)–Zn alloy to multiple mechanisms caused by RE–Zn bonding—stabilization of a large volume fraction of strengthening precipitates on slip planes, increase in vacancy diffusion barrier, reduction in activated cross-slip, and enhancement of covalent character and bond strength around Zn solutes along the c-axis of Mg. We report that increased vacancy diffusion barrier, which correlates with the observed 25% increase in interplanar bond stiffness, primarily enhances the high-temperature creep life. Thus, we demonstrate that an approach of local, randomized tailoring of bond stiffness via microalloying enhances creep performance of alloys. Adding very small amounts of zinc to magnesium alloys containing rare earth elements dramatically improves their creep life. Here, the authors use first principles calculations and atomic-scale characterization to show that this is due to stiff covalent bonding of zinc and rare earth elements such as neodymium.

394 citations

Journal ArticleDOI
TL;DR: This study reports on the molecular dynamics study of the translocation of fullerene C60 and its derivative C60(OH)20 across a model cell membrane (dipalmitoylphosphatidylcholine or DPPC bilayer) and offers a mechanistic explanation of that difference and for the reduced acute toxicity of functionalized fullerenes.
Abstract: Obtaining an understanding, at the atomic level, of the interaction of nanomaterials with biological systems has recently become an issue of great research interest. Here we report on the molecular dynamics study of the translocation of fullerene C60 and its derivative C60(OH)20 across a model cell membrane (dipalmitoylphosphatidylcholine or DPPC bilayer). The simulation results indicate that, although a pristine C60 molecule can readily "jump" into the bilayer and translocate the membrane within a few milliseconds, the C60(OH)20 molecule can barely penetrate the bilayer. Indeed, the mean translocation time via diffusion for the C60(OH)20 molecule is several orders of magnitude longer than for the former. It was also determined that the two different forms of fullerenes, when adsorbed into/onto the bilayer, affected the membrane structure differently. This study offers a mechanistic explanation of that difference and for the reduced acute toxicity of functionalized fullerenes.

393 citations


Authors

Showing all 12053 results

NameH-indexPapersCitations
Steven N. Blair165879132929
Scott D. Solomon1371145103041
Richard A. Dixon12660371424
Thomas E. Mallouk12254952593
Hong-Cai Zhou11448966320
Qian Wang108214865557
Boris I. Yakobson10744345174
J. N. Reddy10692666940
David Spiegel10673346276
Charles A. Nelson10355740352
Robert J. Vallerand9830141840
Gerald R. Ferris9333229478
Michael H. Abraham8972637868
Jere H. Mitchell8833724386
Alan Needleman8637339180
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202390
2022300
20211,795
20201,769
20191,644
20181,484