scispace - formally typeset
Search or ask a question
Institution

University of Notre Dame

EducationNotre Dame, Indiana, United States
About: University of Notre Dame is a education organization based out in Notre Dame, Indiana, United States. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 22238 authors who have published 55201 publications receiving 2032925 citations. The organization is also known as: University of Notre Dame du Lac & University of Notre Dame, South Bend.


Papers
More filters
Journal ArticleDOI
TL;DR: Two major findings are highlighted: ability to tune the photoelectrochemical response and photoconversion efficiency via size control of CdSe quantum dots and improvement in the photoconversions efficiency by facilitating the charge transport through TiO2 nanotube architecture.
Abstract: Different-sized CdSe quantum dots have been assembled on TiO2 films composed of particle and nanotube morphologies using a bifunctional linker molecule. Upon band-gap excitation, CdSe quantum dots inject electrons into TiO2 nanoparticles and nanotubes, thus enabling the generation of photocurrent in a photoelectrochemical solar cell. The results presented in this study highlight two major findings: (i) ability to tune the photoelectrochemical response and photoconversion efficiency via size control of CdSe quantum dots and (ii) improvement in the photoconversion efficiency by facilitating the charge transport through TiO2 nanotube architecture. The maximum IPCE (photon-to-charge carrier generation efficiency) obtained with 3 nm diameter CdSe nanoparticles was 35% for particulate TiO2 and 45% for tubular TiO2 morphology. The maximum IPCE observed at the excitonic band increases with decreasing particle size, whereas the shift in the conduction band to more negative potentials increases the driving force and favors fast electron injection. The maximum power-conversion efficiency

1,608 citations

Journal ArticleDOI
TL;DR: A bipartite graph composed of US Food and Drug Administration–approved drugs and proteins linked by drug–target binary associations is built, showing an overabundance of 'follow-on' drugs, that is, drugs that target already targeted proteins.
Abstract: The global set of relationships between protein targets of all drugs and all disease-gene products in the human protein-protein interaction or 'interactome' network remains uncharacterized. We built a bipartite graph composed of US Food and Drug Administration-approved drugs and proteins linked by drug-target binary associations. The resulting network connects most drugs into a highly interlinked giant component, with strong local clustering of drugs of similar types according to Anatomical Therapeutic Chemical classification. Topological analyses of this network quantitatively showed an overabundance of 'follow-on' drugs, that is, drugs that target already targeted proteins. By including drugs currently under investigation, we identified a trend toward more functionally diverse targets improving polypharmacology. To analyze the relationships between drug targets and disease-gene products, we measured the shortest distance between both sets of proteins in current models of the human interactome network. Significant differences in distance were found between etiological and palliative drugs. A recent trend toward more rational drug design was observed.

1,592 citations

Journal ArticleDOI
Daniel J. Benjamin1, James O. Berger2, Magnus Johannesson1, Magnus Johannesson3, Brian A. Nosek4, Brian A. Nosek5, Eric-Jan Wagenmakers6, Richard A. Berk7, Kenneth A. Bollen8, Björn Brembs9, Lawrence D. Brown7, Colin F. Camerer10, David Cesarini11, David Cesarini12, Christopher D. Chambers13, Merlise A. Clyde2, Thomas D. Cook14, Thomas D. Cook15, Paul De Boeck16, Zoltan Dienes17, Anna Dreber3, Kenny Easwaran18, Charles Efferson19, Ernst Fehr20, Fiona Fidler21, Andy P. Field17, Malcolm R. Forster22, Edward I. George7, Richard Gonzalez23, Steven N. Goodman24, Edwin J. Green25, Donald P. Green26, Anthony G. Greenwald27, Jarrod D. Hadfield28, Larry V. Hedges15, Leonhard Held20, Teck-Hua Ho29, Herbert Hoijtink30, Daniel J. Hruschka31, Kosuke Imai32, Guido W. Imbens24, John P. A. Ioannidis24, Minjeong Jeon33, James Holland Jones34, Michael Kirchler35, David Laibson36, John A. List37, Roderick J. A. Little23, Arthur Lupia23, Edouard Machery38, Scott E. Maxwell39, Michael A. McCarthy21, Don A. Moore40, Stephen L. Morgan41, Marcus R. Munafò42, Shinichi Nakagawa43, Brendan Nyhan44, Timothy H. Parker45, Luis R. Pericchi46, Marco Perugini47, Jeffrey N. Rouder48, Judith Rousseau49, Victoria Savalei50, Felix D. Schönbrodt51, Thomas Sellke52, Betsy Sinclair53, Dustin Tingley36, Trisha Van Zandt16, Simine Vazire54, Duncan J. Watts55, Christopher Winship36, Robert L. Wolpert2, Yu Xie32, Cristobal Young24, Jonathan Zinman44, Valen E. Johnson18, Valen E. Johnson1 
University of Southern California1, Duke University2, Stockholm School of Economics3, University of Virginia4, Center for Open Science5, University of Amsterdam6, University of Pennsylvania7, University of North Carolina at Chapel Hill8, University of Regensburg9, California Institute of Technology10, New York University11, Research Institute of Industrial Economics12, Cardiff University13, Mathematica Policy Research14, Northwestern University15, Ohio State University16, University of Sussex17, Texas A&M University18, Royal Holloway, University of London19, University of Zurich20, University of Melbourne21, University of Wisconsin-Madison22, University of Michigan23, Stanford University24, Rutgers University25, Columbia University26, University of Washington27, University of Edinburgh28, National University of Singapore29, Utrecht University30, Arizona State University31, Princeton University32, University of California, Los Angeles33, Imperial College London34, University of Innsbruck35, Harvard University36, University of Chicago37, University of Pittsburgh38, University of Notre Dame39, University of California, Berkeley40, Johns Hopkins University41, University of Bristol42, University of New South Wales43, Dartmouth College44, Whitman College45, University of Puerto Rico46, University of Milan47, University of California, Irvine48, Paris Dauphine University49, University of British Columbia50, Ludwig Maximilian University of Munich51, Purdue University52, Washington University in St. Louis53, University of California, Davis54, Microsoft55
TL;DR: The default P-value threshold for statistical significance is proposed to be changed from 0.05 to 0.005 for claims of new discoveries in order to reduce uncertainty in the number of discoveries.
Abstract: We propose to change the default P-value threshold for statistical significance from 0.05 to 0.005 for claims of new discoveries.

1,586 citations

Journal ArticleDOI
TL;DR: This tutorial review highlights the surface plasmon resonance peaks of gold nanostructures by comparing four typical examples: nanospheres, nanorods, nanoshells, and nanocages.
Abstract: The surface plasmon resonance peaks of gold nanostructures can be tuned from the visible to the near infrared region by controlling the shape and structure (solid vs. hollow). In this tutorial review we highlight this concept by comparing four typical examples: nanospheres, nanorods, nanoshells, and nanocages. A combination of this optical tunability with the inertness of gold makes gold nanostructures well suited for various biomedical applications.

1,579 citations

Journal ArticleDOI
Georges Aad1, Brad Abbott2, Jalal Abdallah3, Ovsat Abdinov4  +5117 moreInstitutions (314)
TL;DR: A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4ℓ decay channels.
Abstract: A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4l decay channels. The results are obtained from a simultaneous fit to the reconstructed invariant mass peaks in the two channels and for the two experiments. The measured masses from the individual channels and the two experiments are found to be consistent among themselves. The combined measured mass of the Higgs boson is mH=125.09±0.21 (stat)±0.11 (syst) GeV.

1,567 citations


Authors

Showing all 22586 results

NameH-indexPapersCitations
George Davey Smith2242540248373
David Miller2032573204840
Patrick O. Brown183755200985
Dorret I. Boomsma1761507136353
Chad A. Mirkin1641078134254
Darien Wood1602174136596
Wei Li1581855124748
Timothy C. Beers156934102581
Todd Adams1541866143110
Albert-László Barabási152438200119
T. J. Pearson150895126533
Amartya Sen149689141907
Christopher Hill1441562128098
Tim Adye1431898109010
Teruki Kamon1422034115633
Network Information
Related Institutions (5)
University of Illinois at Urbana–Champaign
225.1K papers, 10.1M citations

90% related

University of Maryland, College Park
155.9K papers, 7.2M citations

89% related

University of Texas at Austin
206.2K papers, 9M citations

89% related

Pennsylvania State University
196.8K papers, 8.3M citations

89% related

Princeton University
146.7K papers, 9.1M citations

89% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023115
2022543
20212,777
20202,925
20192,774
20182,624