University of Notre Dame

About: University of Notre Dame is a education organization based out in Notre Dame, Indiana, United States. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 22238 authors who have published 55201 publications receiving 2032925 citations. The organization is also known as: University of Notre Dame du Lac & University of Notre Dame, South Bend.

Diameter of the World-Wide Web

Abstract: Despite its increasing role in communication, the World-Wide Web remains uncontrolled: any individual or institution can create a website with any number of documents and links. This unregulated growth leads to a huge and complex web, which becomes a large directed graph whose vertices are documents and whose edges are links (URLs) that point from one document to another. The topology of this graph determines the web's connectivity and consequently how effectively we can locate information on it. But its enormous size (estimated to be at least 8×108 documents1) and the continual changing of documents and links make it impossible to catalogue all the vertices and edges.

Progress, Challenges, and Opportunities in Two-Dimensional Materials Beyond Graphene

Abstract: Graphene’s success has shown that it is possible to create stable, single and few-atom-thick layers of van der Waals materials, and also that these materials can exhibit fascinating and technologically useful properties. Here we review the state-of-the-art of 2D materials beyond graphene. Initially, we will outline the different chemical classes of 2D materials and discuss the various strategies to prepare single-layer, few-layer, and multilayer assembly materials in solution, on substrates, and on the wafer scale. Additionally, we present an experimental guide for identifying and characterizing single-layer-thick materials, as well as outlining emerging techniques that yield both local and global information. We describe the differences that occur in the electronic structure between the bulk and the single layer and discuss various methods of tuning their electronic properties by manipulating the surface. Finally, we highlight the properties and advantages of single-, few-, and many-layer 2D materials in...

Hierarchical Organization of Modularity in Metabolic Networks

Abstract: Spatially or chemically isolated functional modules composed of several cellular components and carrying discrete functions are considered fundamental building blocks of cellular organization, but their presence in highly integrated biochemical networks lacks quantitative support Here, we show that the metabolic networks of 43 distinct organisms are organized into many small, highly connected topologic modules that combine in a hierarchical manner into larger, less cohesive units, with their number and degree of clustering following a power law Within Escherichia coli, the uncovered hierarchical modularity closely overlaps with known metabolic functions The identified network architecture may be generic to system-level cellular organization

The B73 Maize Genome: Complexity, Diversity, and Dynamics

Abstract: We report an improved draft nucleotide sequence of the 2.3-gigabase genome of maize, an important crop plant and model for biological research. Over 32,000 genes were predicted, of which 99.8% were placed on reference chromosomes. Nearly 85% of the genome is composed of hundreds of families of transposable elements, dispersed nonuniformly across the genome. These were responsible for the capture and amplification of numerous gene fragments and affect the composition, sizes, and positions of centromeres. We also report on the correlation of methylation-poor regions with Mu transposon insertions and recombination, and copy number variants with insertions and/or deletions, as well as how uneven gene losses between duplicated regions were involved in returning an ancient allotetraploid to a genetically diploid state. These analyses inform and set the stage for further investigations to improve our understanding of the domestication and agricultural improvements of maize.

Trust as a Social Reality

Abstract: Although trust is an underdeveloped concept in sociology, promising theoretical formulations are available in the recent work of Luhmann and Barber. This sociological version complements the psychological and attitudinal conceptualizations of experimental and survey researchers. Trust is seen to include both emotional and cognitive dimensions and to function as a deep assumption underwriting social order. Contemporary examples such as lying, family exchange, monetary attitudes, and litigation illustrate the centrality of trust as a sociological reality. In recent years, sociologists have begun to treat trust as a sociological topic (e.g., Conviser; Garfinkel; Haas and Deseran; Henslin; Holzner; Strub and Priest; Weigert,a,b). Indeed, two short and powerful books, Niklas Luhmann's Trust and Pauoer (1979) and Bernard Barber's The Logic and Limits of Trust (1983), have placed trust at the center of sociological theorizing about contemporary society. Nevertheless, we agree with Luhmann's lament that there is a "regrettably sparse literature which has trust as its main theme within sociology" (8). There is a large quantity of research on trust by experimental psychologists and political scientists, which, however, appears theoretically unintegrated and incomplete from the standpoint of a sociology of trust. These researchers typically conceptualize trust as a psychological event within the individual rather than as an intersubjective or systemic social reality. They also tend to use methodological approaches that reduce trust to its cognitive content through psychometric scaling techniques or to its behavioral expressions in laboratory settings. Luhmann and Barber, on the other hand, present trust as an irreducible and multidimiensional so