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Institution

University of Oklahoma

EducationNorman, Oklahoma, United States
About: University of Oklahoma is a education organization based out in Norman, Oklahoma, United States. It is known for research contribution in the topics: Population & Radar. The organization has 25269 authors who have published 52609 publications receiving 1821706 citations. The organization is also known as: OU & Oklahoma University.


Papers
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Journal ArticleDOI
TL;DR: This level of novel phylogenetic diversity indicates that the understanding of the functions of soil microorganisms, even those belonging to phyla with numerous and diverse well-characterized cultured representatives such as the Proteobacteria, remains far from adequate.
Abstract: Small subunit (16S) rRNA gene surveys generating near full-length 16S rRNA clones offer a unique opportunity for in-depth phylogenetic analysis to highlight the breadth of diversity within various major bacterial phyla encountered in soil. This study offers a detailed phylogenetic analysis of the Proteobacteria-affiliated clones identified from 13,001 nearly full-length 16S rRNA gene clones derived from Oklahoma tall-grass prairie soil. Proteobacteria was the most abundant phylum in the community, and comprised 25% of the total clones. The most abundant and diverse class within the Proteobacteria was Alphaproteobacteria, followed by the Delta-, Beta- and Gammaproteobacteria. Members of the Epsilon- and Zetaproteobacteria were not detected in the dataset. Our analysis identified 15 novel order-level and 48 novel family-level Proteobacteria lineages. In addition, we show that the majority of Proteobacteria clones in the dataset belong to orders and families containing no described cultivated representatives (50% and 65%, respectively). An examination of the ecological distribution of the six most abundant Proteobacteria lineages in this dataset with no characterized pure culture representatives provided important information regarding their global distribution and environmental preferences. This level of novel phylogenetic diversity indicates that our understanding of the functions of soil microorganisms, even those belonging to phyla with numerous and diverse well-characterized cultured representatives such as the Proteobacteria, remains far from adequate.

374 citations

Journal ArticleDOI
TL;DR: In this paper, a spectral sequence among Type Ia supernovae (SN Ia's) is presented based on the systematic variation of several features seen in the near-maximum light spectrum.
Abstract: In this Letter we present evidence for a spectral sequence among Type Ia supernovae (SN Ia's). The sequence is based on the systematic variation of several features seen in the near-maximum light spectrum. This sequence is analogous to the recently noted photometric sequence among SN Ia's which shows a relationship between the peak brightness of a SN Ia and the shape of its light curve. In addition to the observational evidence we present a partial theoretical explanation for the sequence. This has been achieved by producing a series of non-LTE synthetic spectra in which only the effective temperature is varied. The synthetic sequence nicely reproduces most of the differences seen in the observed one and presumably corresponds to the amount of 56Ni produced in the explosion.

373 citations

Journal ArticleDOI
TL;DR: There is little evidence that links high protein intakes to increased risk for impaired kidney function in healthy individuals, however, renal function decreases with age, and high protein intake is contraindicated in individuals with renal disease.

373 citations

Journal ArticleDOI
TL;DR: In this article, the authors review the recent controversy concerning temperature corrections to the Casimir force between real metal surfaces, and present a summary of new improvements to the proximity force approximation and a synopsis of the current experimental situation.
Abstract: The phenomena implied by the existence of quantum vacuum fluctuations, grouped under the title of the Casimir effect, are reviewed, with emphasis on new results discovered in the past four years. The Casimir force between parallel plates is rederived as the strong-coupling limit of δ-function potential planes. The role of surface divergences is clarified. A summary of effects relevant to measurements of the Casimir force between real materials is given, starting from a geometrical optics derivation of the Lifshitz formula, and including a rederivation of the Casimir–Polder forces. A great deal of attention is given to the recent controversy concerning temperature corrections to the Casimir force between real metal surfaces. A summary of new improvements to the proximity force approximation is given, followed by a synopsis of the current experimental situation. New results on Casimir self-stress are reported, again based on δ-function potentials. Progress in understanding divergences in the self-stress of dielectric bodies is described, in particular the status of a continuing calculation of the self-stress of a dielectric cylinder. Casimir effects for solitons, and the status of the so-called dynamical Casimir effect, are summarized. The possibilities of understanding dark energy, strongly constrained by both cosmological and terrestrial experiments, in terms of quantum fluctuations are discussed. Throughout, the centrality of quantum vacuum energy in fundamental physics is emphasized.

372 citations

Journal ArticleDOI
TL;DR: It is found that specific depletion of CD169+ macrophages markedly reduced the number of erythroblasts in the bone marrow but did not result in overt anemia under homeostatic conditions, probably because of concomitant alterations in red blood cell clearance.
Abstract: A role for macrophages in erythropoiesis was suggested several decades ago when erythroblastic islands in the bone marrow, composed of a central macrophage surrounded by developing erythroblasts, were described. However, the in vivo role of macrophages in erythropoiesis under homeostatic conditions or in disease remains unclear. We found that specific depletion of CD169(+) macrophages markedly reduced the number of erythroblasts in the bone marrow but did not result in overt anemia under homeostatic conditions, probably because of concomitant alterations in red blood cell clearance. However, CD169(+) macrophage depletion significantly impaired erythropoietic recovery from hemolytic anemia, acute blood loss and myeloablation. Furthermore, macrophage depletion normalized the erythroid compartment in a JAK2(V617F)-driven mouse model of polycythemia vera, suggesting that erythropoiesis in polycythemia vera remains under the control of macrophages in the bone marrow and splenic microenvironments. These results indicate that CD169(+) macrophages promote late erythroid maturation and that modulation of the macrophage compartment may be a new strategy to treat erythropoietic disorders.

372 citations


Authors

Showing all 25490 results

NameH-indexPapersCitations
Ronald C. Kessler2741332328983
Michael A. Strauss1851688208506
Derek R. Lovley16858295315
Ashok Kumar1515654164086
Peter J. Schwartz147647107695
Peter Buchholz143118192101
Robert Hirosky1391697106626
Elizabeth Barrett-Connor13879373241
Brad Abbott137156698604
Lihong V. Wang136111872482
Itsuo Nakano135153997905
Phillip Gutierrez133139196205
P. Skubic133157397343
Elizaveta Shabalina133142192273
Richard Brenner133110887426
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202392
2022348
20212,425
20202,481
20192,433
20182,396