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Institution

University of Oklahoma

EducationNorman, Oklahoma, United States
About: University of Oklahoma is a education organization based out in Norman, Oklahoma, United States. It is known for research contribution in the topics: Population & Radar. The organization has 25269 authors who have published 52609 publications receiving 1821706 citations. The organization is also known as: OU & Oklahoma University.


Papers
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Journal ArticleDOI
07 Jun 2016-Sensors
TL;DR: Researchers are provided with information to compare the existing low-power communication technologies that can potentially support the rapid development and deployment of WBAN systems, and mainly focuses on remote monitoring of elderly or chronically ill patients in residential environments.
Abstract: Current progress in wearable and implanted health monitoring technologies has strong potential to alter the future of healthcare services by enabling ubiquitous monitoring of patients. A typical health monitoring system consists of a network of wearable or implanted sensors that constantly monitor physiological parameters. Collected data are relayed using existing wireless communication protocols to a base station for additional processing. This article provides researchers with information to compare the existing low-power communication technologies that can potentially support the rapid development and deployment of WBAN systems, and mainly focuses on remote monitoring of elderly or chronically ill patients in residential environments.

266 citations

Journal ArticleDOI
TL;DR: In this article, the authors presented the results of a study of the evolution of the Mississippi Valley-type (MVT) lead-zinc ores in the Earth's crust and showed that these ores formed mainly during large contractional tectonic events at restricted times in the history of the Earth.
Abstract: Remarkable advances in age dating Mississippi Valley-type (MVT) lead–zinc deposits provide a new opportunity to understand how and where these deposits form in the Earth's crust. These dates are summarized and examined in a framework of global tectonics, paleogeography, fluid migration, and paleoclimate. Nineteen districts have been dated by paleomagnetic and/or radiometric methods. Of the districts that have both paleomagnetic and radiometric dates, only the Pine Point and East Tennessee districts have significant disagreements. This broad agreement between paleomagnetic and radiometric dates provides added confidence in the dating techniques used. The new dates confirm the direct connection between the genesis of MVT lead–zinc ores with global-scale tectonic events. The dates show that MVT deposits formed mainly during large contractional tectonic events at restricted times in the history of the Earth. Only the deposits in the Lennard Shelf of Australia and Nanisivik in Canada have dates that correspond to extensional tectonic events. The most important period for MVT genesis was the Devonian to Permian time, which corresponds to a series of intense tectonic events during the assimilation of Pangea. The second most important period for MVT genesis was Cretaceous to Tertiary time when microplate assimilation affected the western margin of North America and Africa–Eurasia. There is a notable paucity of MVT lead–zinc ore formation following the breakup of Rodinia and Pangea. Of the five MVT deposits hosted in Proterozoic rocks, only the Nanisivik deposit has been dated as Proterozoic. The contrast in abundance between SEDEX and MVT lead–zinc deposits in the Proterozoic questions the frequently suggested notion that the two types of ores share similar genetic paths. The ages of MVT deposits, when viewed with respect to the orogenic cycle in the adjacent orogen suggest that no single hydrologic model can be universally applied to the migration of the ore fluids. However, topographically driven models best explain most MVT districts. The migration of MVT ore fluids is not a natural consequence of basin evolution; rather, MVT districts formed mainly where platform carbonates had some hydrological connection to orogenic belts. There may be a connection between paleoclimate and the formation of some MVT deposits. This possible relationship is suggested by the dominance of evaporated seawater in fluid inclusions in MVT ores, by hydrological considerations that include the need for multiple-basin volumes of ore fluid to form most MVT districts, and the need for adequate precipitation to provide sufficient topographic head for topographically-driven fluid migration. Paleoclimatic conditions that lead to formation of evaporite conditions but yet have adequate precipitation to form large hydrological systems are most commonly present in low latitudes. For the MVT deposits and districts that have been dated, more than 75% of the combined metal produced are from deposits that have dates that correspond to assembly of Pangea in Devonian through Permian time. The exceptional endowment of Pangea and especially, North America with MVT lead–zinc deposits may be explained by the following: (1) Laurentia, which formed the core of North America, stayed in low latitudes during the Paleozoic, which allowed the development of vast carbonate platforms; (2) intense orogenic activity during the assembly of Pangea created ground preparation for many MVT districts through far-field deformation of the craton; (3) uplifted orogenic belts along Pangean suture zones established large-scale migration of basin fluids; and (4) the location of Pangea in low latitudes with paleoclimates with high evaporation rates led to the formation of brines by the evaporation of seawater and infiltration of these brines into deep basin aquifers during Pangean orogenic events.

266 citations

Journal ArticleDOI
TL;DR: In this article, the authors developed a framework for assessing how marketing actions affect customers' lifetime value to the firm, which is organized around four critical actions that firms must take to effectively manage the asset value of the customer base: database creation, market segmentation, forecasting customer purchase behavior and resource allocation.
Abstract: This article develops a framework for assessing how marketing actions affect customers’lifetime value to the firm. The framework is organized around four critical actions that firms must take to effectively manage the asset value of the customer base: database creation, market segmentation, forecasting customer purchase behavior, and resource allocation. In this framework, customer lifetime value is treated as a dynamic construct, that is, it influences the eventual allocation of marketing resources but is also influenced by that allocation. By viewing customers as assets and systematically managing these assets, a firm can identify the most appropriate marketing actions to acquire, maintain, and enhance customer assets and thereby maximize financial returns. The article discusses in detail how to assess customer lifetime value and manage customers as assets. Then, it identifies key research challenges in studying customer asset management and the managerial challenges associated with implementing effecti...

266 citations

Journal ArticleDOI
TL;DR: Evaluation of candidate loci in a large kindred segregating autosomal dominant ToF with reduced penetrance culminated in identification of a missense mutation (G274D) in JAG1, the gene encoding jagged1, a Notch ligand expressed in the developing right heart, suggesting thatJAG1 mutations may contribute significantly to common variants of right heart obstructive disease.
Abstract: Tetralogy of Fallot (ToF) is the most common form of complex congenital heart disease, occurring in approximately 1 in 3000 live births. Evaluation of candidate loci in a large kindred segregating autosomal dominant ToF with reduced penetrance culminated in identification of a missense mutation (G274D) in JAG1, the gene encoding jagged1, a Notch ligand expressed in the developing right heart. Nine of eleven mutation carriers manifested cardiac disease, including classic ToF, ventricular septal defect with aortic dextroposition and isolated peripheral pulmonic stenosis (PPS). All forms of ToF were represented, including variants with pulmonic stenosis, pulmonic atresia and absent pulmonary valve. No individual within this family met diagnostic criteria for any previously described clinical syndrome, including Alagille syndrome (AGS), caused by haploinsufficiency for jagged1. All mutation carriers had characteristic but variable facial features, including long, narrow and upslanting palpebral fissures, prominent nasal bridge, square dental arch and broad, prominent chin. This appearance was distinct from that of unaffected family members and typical AGS patients. The glycine corresponding to position 274 is highly conserved in other epidermal growth factor-like domains of jagged1 and in those of other proteins. Its substitution in other proteins has been associated with mild or atypical variants of disease. These data support either a relative loss-of-function or a gain-of-function pathogenetic mechanism in this family and suggest that JAG1 mutations may contribute significantly to common variants of right heart obstructive disease.

266 citations

Journal ArticleDOI
TL;DR: This Consensus Report characterizes type 2 diabetes in children, evaluates the fundamental differences between childhood and adult disease, describes the current therapeutic options, and discusses challenges to and approaches for developing new treatments.
Abstract: Type 2 diabetes is a significant and increasing burden in adolescents and young adults. Clear strategies for research, prevention, and treatment of the disease in these vulnerable patients are needed. Evidence suggests that type 2 diabetes in children is different not only from type 1 but also from type 2 diabetes in adults. Understanding the unique pathophysiology of type 2 diabetes in youth, as well as the risk of complications and the psychosocial impact, will enable industry, academia, funding agencies, advocacy groups, and regulators to collectively evaluate both current and future research, treatment, and prevention approaches. This Consensus Report characterizes type 2 diabetes in children, evaluates the fundamental differences between childhood and adult disease, describes the current therapeutic options, and discusses challenges to and approaches for developing new treatments.

266 citations


Authors

Showing all 25490 results

NameH-indexPapersCitations
Ronald C. Kessler2741332328983
Michael A. Strauss1851688208506
Derek R. Lovley16858295315
Ashok Kumar1515654164086
Peter J. Schwartz147647107695
Peter Buchholz143118192101
Robert Hirosky1391697106626
Elizabeth Barrett-Connor13879373241
Brad Abbott137156698604
Lihong V. Wang136111872482
Itsuo Nakano135153997905
Phillip Gutierrez133139196205
P. Skubic133157397343
Elizaveta Shabalina133142192273
Richard Brenner133110887426
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202392
2022348
20212,425
20202,481
20192,433
20182,396