Institution
University of Oklahoma
Education•Norman, Oklahoma, United States•
About: University of Oklahoma is a education organization based out in Norman, Oklahoma, United States. It is known for research contribution in the topics: Population & Radar. The organization has 25269 authors who have published 52609 publications receiving 1821706 citations. The organization is also known as: OU & Oklahoma University.
Papers published on a yearly basis
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Harvard University1, Massachusetts Institute of Technology2, University of Calabria3, Khalifa University4, Colorado School of Mines5, University of Oklahoma6, New Mexico State University7, United States Environmental Protection Agency8, University of Arizona9, University of Auckland10, National University of Singapore11
TL;DR: Challenges still facing membrane-based potable reuse applications, including chemical and biological contaminant removal, membrane fouling, and public perception, are highlighted as areas in need of further research and development.
421 citations
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TL;DR: In this article, a theoretically improved model incorporating the relevant mechanisms of gas retention and transport in gas-bearing shale formations is presented for determination of intrinsic gas permeability and diffusivity, by considering the various flow regimes according to a unified Hagen-Poiseuille-type equation, fully compressible treatment of gas and shale properties, and numerical solution of the nonlinear pressure equation.
Abstract: A theoretically improved model incorporating the relevant mechanisms of gas retention and transport in gas-bearing shale formations is presented for determination of intrinsic gas permeability and diffusivity. This is accomplished by considering the various flow regimes according to a unified Hagen–Poiseuille-type equation, fully compressible treatment of gas and shale properties, and numerical solution of the non-linear pressure equation. The present model can accommodate a wide range of fundamental flow mechanisms, such as continuum, slip, transition, and free molecular flow, depending on the prevailing flow conditions characterized by the Knudsen number. The model indicates that rigorous determination of shale-gas permeability and diffusivity requires the characterization of various important parameters included in the present phenomenological modeling approach, many of which are not considered in previous studies. It is demonstrated that the improved model matches a set of experimental data better than a previous attempt. It is concluded that the improved model provides a more accurate means of analysis and interpretation of the pressure-pulse decay tests than the previous models which inherently consider a Darcian flow and neglect the variation of parameters with pressure.
420 citations
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01 Jan 1971420 citations
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University of Florida1, University of Minnesota2, University of Oklahoma3, United States Department of Agriculture4, Donald Danforth Plant Science Center5, Stony Brook University6, Eckerd College7, Purdue University8, Cold Spring Harbor Laboratory9, University of Rhode Island10, University of California, Berkeley11, Colorado State University12, University of California, Riverside13, University of California, Davis14, Boyce Thompson Institute for Plant Research15, Stanford University16, Iowa State University17, University of Missouri18, University of Tennessee19
TL;DR: The state of plant transformation is reviewed and innovations needed to enable genome editing in crops are pointed to, including a potential game-changer in crop genetics when plant transformation systems are optimized.
Abstract: Plant transformation has enabled fundamental insights into plant biology and revolutionized commercial agriculture. Unfortunately, for most crops, transformation and regeneration remain arduous even after more than thirty years of technological advances. Genome editing provides new opportunities to enhance crop productivity, but relies on genetic transformation and plant regeneration, which are bottlenecks in the process. Herein we review the state of plant transformation and point to innovations needed to enable genome editing in crops. Plant tissue culture methods need optimization and simplification for efficiency and minimize time in culture. Currently, specialized facilities exist for crop transformation. Single cell and robotic techniques should be developed for high throughput genomic screens. Utilization of plant genes involved in developmental reprogramming, wound response, and/or homologous recombination could boost recovery of transformed plants. Engineering universal Agrobacterium strains and recruitment of other microbes, such as Ensifer or Rhizobium, could facilitate delivery of DNA and proteins into plant cells. Synthetic biology should be employed for de novo design of transformation systems. Genome editing is a potential game-changer in crop genetics when plant transformation systems are optimized.
419 citations
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TL;DR: It is indicated that CF sputum readily supports high-density P. aeruginosa growth and multiple signals, which reduce swimming motility and prematurely activate the Pseudomonas quinolone signal cell-to-cell signaling cascade in P. Aerug inosa, are present in CF spUTum.
Abstract: The opportunistic human pathogen Pseudomonas aeruginosa causes persistent airway infections in patients with cystic fibrosis (CF). To establish these chronic infections, P. aeruginosa must grow and proliferate within the highly viscous sputum in the lungs of CF patients. In this study, we used Affymetrix GeneChip microarrays to investigate the physiology of P. aeruginosa grown using CF sputum as the sole source of carbon and energy. Our results indicate that CF sputum readily supports high-density P. aeruginosa growth. Furthermore, multiple signals, which reduce swimming motility and prematurely activate the Pseudomonas quinolone signal cell-to-cell signaling cascade in P. aeruginosa, are present in CF sputum. P. aeruginosa factors critical for lysis of the common CF lung inhabitant Staphylococcus aureus were also induced in CF sputum and increased the competitiveness of P. aeruginosa during polymicrobial growth in CF sputum.
419 citations
Authors
Showing all 25490 results
Name | H-index | Papers | Citations |
---|---|---|---|
Ronald C. Kessler | 274 | 1332 | 328983 |
Michael A. Strauss | 185 | 1688 | 208506 |
Derek R. Lovley | 168 | 582 | 95315 |
Ashok Kumar | 151 | 5654 | 164086 |
Peter J. Schwartz | 147 | 647 | 107695 |
Peter Buchholz | 143 | 1181 | 92101 |
Robert Hirosky | 139 | 1697 | 106626 |
Elizabeth Barrett-Connor | 138 | 793 | 73241 |
Brad Abbott | 137 | 1566 | 98604 |
Lihong V. Wang | 136 | 1118 | 72482 |
Itsuo Nakano | 135 | 1539 | 97905 |
Phillip Gutierrez | 133 | 1391 | 96205 |
P. Skubic | 133 | 1573 | 97343 |
Elizaveta Shabalina | 133 | 1421 | 92273 |
Richard Brenner | 133 | 1108 | 87426 |