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Institution

University of Paris

EducationParis, France
About: University of Paris is a education organization based out in Paris, France. It is known for research contribution in the topics: Population & Transplantation. The organization has 102426 authors who have published 174180 publications receiving 5041753 citations. The organization is also known as: Sorbonne.


Papers
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Journal ArticleDOI
TL;DR: In this article, the induced gluon radiation of a high-energy quark in a finite-size QCD medium is studied, and the radiative energy loss ΔE¯¯¯¯q∝L�2, where L is the distance traveled by quarks in the medium.
Abstract: The induced gluon radiation of a high-energy quark in a finite-size QCD medium is studied. For a sufficiently energetic quark produced inside a medium we find the radiative energy loss ΔE q∝L 2, where L is the distance traveled by quark in the medium. It has a weak dependence on the initial quark energy E q. The L 2 dependence turns to L 1 as the quark energy decreases. Numerical calculations are performed for a cold nuclear matter and a hot quark-gluon plasma. For a quark incident on a nucleus we predict ΔE q ≈0.1E q (L/10fm) β , with β close to unity.

569 citations

Journal ArticleDOI
TL;DR: D-VTd before and after autologous stem-cell transplantation improved depth of response and progression-free survival with acceptable safety and CASSIOPEIA is the first study showing the clinical benefit of daratumumab plus standard of care in transplant-eligible patients with newly diagnosed multiple myeloma.

569 citations

Journal ArticleDOI
Douglas M. Ruderfer1, Stephan Ripke2, Stephan Ripke3, Stephan Ripke4  +628 moreInstitutions (156)
14 Jun 2018-Cell
TL;DR: For the first time, specific loci that distinguish between BD and SCZ are discovered and polygenic components underlying multiple symptom dimensions are identified that point to the utility of genetics to inform symptomology and potential treatment.

569 citations

Journal ArticleDOI
TL;DR: The last few years have witnessed important new developments in the theory and practice of pattern classification, see as discussed by the authors for a survey of the main new ideas that have lead to these important recent developments.
Abstract: The last few years have witnessed important new developments in the theory and practice of pattern classification. We intend to survey some of the main new ideas that have lead to these important recent developments. Resume. Durant ces dernieres annees, la theorie et la pratique de la reconnaissance des formes ont ´e marquees par des developpements originaux. Ce survol presente certaines des principales idees novatrices qui ont conduitces developpements importants.

569 citations

Journal ArticleDOI
TL;DR: The rhythmic control of xenobiotic detoxification provides the molecular basis for the dosing time-dependence of drug toxicities and efficacy and can in turn be used in improving or designing chronotherapeutics for the patients who suffer from many of the major human diseases.
Abstract: The mammalian circadian system is organized in a hierarchical manner in that a central pacemaker in the suprachiasmatic nucleus (SCN) of the brain's hypothalamus synchronizes cellular circadian oscillators in most peripheral body cells. Fasting-feeding cycles accompanying rest-activity rhythms are the major timing cues in the synchronization of many, if not most, peripheral clocks, suggesting that the temporal coordination of metabolism and proliferation is a major task of the mammalian timing system. The inactivation of noxious food components by hepatic, intestinal, and renal detoxification systems is among the metabolic processes regulated in a circadian manner, with the understanding of the involved clock output pathways emerging. The rhythmic control of xenobiotic detoxification provides the molecular basis for the dosing time-dependence of drug toxicities and efficacy. This knowledge can in turn be used in improving or designing chronotherapeutics for the patients who suffer from many of the major human diseases.

568 citations


Authors

Showing all 102613 results

NameH-indexPapersCitations
Guido Kroemer2361404246571
David H. Weinberg183700171424
Paul M. Thompson1832271146736
Chris Sander178713233287
Sophie Henrot-Versille171957157040
Richard H. Friend1691182140032
George P. Chrousos1691612120752
Mika Kivimäki1661515141468
Martin Karplus163831138492
William J. Sandborn1621317108564
Darien Wood1602174136596
Monique M.B. Breteler15954693762
Paul Emery1581314121293
Wolfgang Wagner1562342123391
Joao Seixas1531538115070
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202376
2022602
202116,433
202015,008
201911,047
20189,090