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Institution

University of Paris

EducationParis, France
About: University of Paris is a education organization based out in Paris, France. It is known for research contribution in the topics: Population & Transplantation. The organization has 102426 authors who have published 174180 publications receiving 5041753 citations. The organization is also known as: Sorbonne.


Papers
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Journal ArticleDOI
TL;DR: Angiotensin-neprilysin inhibition prevents the clinical progression of surviving patients with heart failure more effectively than angiotens in-converting enzyme inhibition.
Abstract: Background—Clinical trials in heart failure have focused on the improvement in symptoms or decreases in the risk of death and other cardiovascular events. Little is known about the effect of drugs ...

532 citations

Journal ArticleDOI
Guy Henniart1
TL;DR: In this article, a proof of the Langlands conjectures for a finite extension of the Weil group of F is given, which is more direct than Harris and Taylor's.
Abstract: Let F be a finite extension of ℚ p . For each integer n≥1, we construct a bijection from the set ?F 0 (n) of isomorphism classes of irreducible degree n representations of the (absolute) Weil group of F, onto the set ? F 0 (n) of isomorphism classes of smooth irreducible supercuspidal representations of GL n (F). Those bijections preserve epsilon factors for pairs and hence we obtain a proof of the Langlands conjectures for GL n over F, which is more direct than Harris and Taylor’s. Our approach is global, and analogous to the derivation of local class field theory from global class field theory. We start with a result of Kottwitz and Clozel on the good reduction of some Shimura varieties and we use a trick of Harris, who constructs non-Galois automorphic induction in certain cases.

531 citations

Journal ArticleDOI
TL;DR: The working group proposes the following working definition of atrial cardiomyopathy: ‘Any complex of structural, architectural, contractile or electrophysiological changes affecting the atria with the potential to produce clinically-relevant manifestations’ (Table 1).

530 citations

Journal ArticleDOI
TL;DR: This first in vivo evidence of a functional role for the H19 locus provides new insights into how genomic imprinting helps to control embryonic growth.
Abstract: The H19 gene produces a non-coding RNA, which is abundantly expressed during embryonic development and down-regulated after birth. Although this gene was discovered over 20 years ago, its function has remained unclear. Only recently a role was identified for the non-coding RNA and/or its microRNA partner, first as a tumour suppressor gene in mice, then as a trans-regulator of a group of co-expressed genes belonging to the imprinted gene network that is likely to control foetal and early postnatal growth in mice. The mechanisms underlying this transcriptional or post-transcriptional regulation remain to be discovered, perhaps by identifying the protein partners of the full-length H19 RNA or the targets of the microRNA. This first in vivo evidence of a functional role for the H19 locus provides new insights into how genomic imprinting helps to control embryonic growth.

530 citations

Journal ArticleDOI
TL;DR: The European Outcome Registry (SOURCE) as discussed by the authors was designed to assess initial post commercial clinical transcatheter aortic valve implantation results of the Edwards SAPIEN valve in consecutive patients in Europe.
Abstract: Background—Transcatheter aortic valve implantation was developed to provide a therapeutic option for patients considered to be ineligible for, and to mitigate mortality and morbidity associated with, high-risk surgical aortic valve replacement. Methods and Results—The Edwards SAPIEN Aortic Bioprosthesis European Outcome (SOURCE) Registry was designed to assess initial post commercial clinical transcatheter aortic valve implantation results of the Edwards SAPIEN valve in consecutive patients in Europe. Cohort 1 consists of 1038 patients enrolled at 32 centers. One-year outcomes are presented. Patients with the transapical approach (n=575) suffered more comorbidities than transfemoral patients (n=463) with a significantly higher logistic EuroSCORE (29% versus 25.8%; P=0.007). These groups are different; therefore, outcomes cannot be directly compared. Total Kaplan Meier 1-year survival was 76.1% overall, 72.1% for transapical and 81.1% for transfemoral patients, and 73.5% of surviving patients were in New Y...

530 citations


Authors

Showing all 102613 results

NameH-indexPapersCitations
Guido Kroemer2361404246571
David H. Weinberg183700171424
Paul M. Thompson1832271146736
Chris Sander178713233287
Sophie Henrot-Versille171957157040
Richard H. Friend1691182140032
George P. Chrousos1691612120752
Mika Kivimäki1661515141468
Martin Karplus163831138492
William J. Sandborn1621317108564
Darien Wood1602174136596
Monique M.B. Breteler15954693762
Paul Emery1581314121293
Wolfgang Wagner1562342123391
Joao Seixas1531538115070
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202376
2022602
202116,433
202015,008
201911,047
20189,090