Institution
University of Peradeniya
Education•Kandy, Sri Lanka•
About: University of Peradeniya is a education organization based out in Kandy, Sri Lanka. It is known for research contribution in the topics: Population & Poison control. The organization has 5970 authors who have published 7388 publications receiving 197002 citations.
Topics: Population, Poison control, Adsorption, Electrolyte, Agriculture
Papers published on a yearly basis
Papers
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TL;DR: A novel combination of traits indicates divergent functioning of Proteaceae species from southern South America, exposed to frequent phosphorus input due to volcanic activity, in contrast with the functioning of south-western Australian Proteidae species that thrive on severely phosphorus-impoverished soils.
Abstract: Summary 1. Proteaceae species in south-western Australia thrive on phosphorus-impoverished soils, employing a phosphorus-mining strategy involving carboxylate-releasing cluster roots. Some develop symptoms of phosphorus toxicity at slightly elevated soil phosphorus concentrations, due to their low capacity to down-regulate phosphorus uptake. In contrast, Proteaceae species in Chile, e.g. Embothrium coccineum J.R. Forst. & G. Forst., occur on volcanic soils, which contain high levels of total phosphorus, but phosphorus availability is low. 2. We hypothesised that the functioning of cluster roots of E. coccineum differs from that of south-western Australian Proteaceae species, in accordance with the difference in soil phosphorus status. With more phosphorus to be gained from the soil with high levels of total phosphorus, we expect less investment in biomass and more release of carboxylates. Furthermore, we hypothesised that E. coccineum regulates its phosphorus-uptake capacity, avoiding phosphorus toxicity when grown at elevated phosphorus levels. To test these hypotheses, E. coccineum seedlings were grown at a range of phosphorus supplies in nutrient solution. 3. We show that E. coccineum allocated at least five times less biomass to cluster roots that released at least nine times more carboxylates per unit cluster root weight compared with south-western Australian species (e.g. Banksia, Hakea). The highest phosphorus supply caused a growth inhibition and high leaf phosphorus concentration, without symptoms of phosphorus toxicity. We accept our hypotheses on the functioning of cluster roots and the high capacity to reduce the net phosphorus uptake in plants grown at a high-phosphorus supply. 4. This novel combination of traits indicates divergent functioning of Proteaceae species from southern South America, exposed to frequent phosphorus input due to volcanic activity, in contrast with the functioning of south-western Australian Proteaceae species that thrive on severely phosphorus-impoverished soils. These traits could explain the functioning of E. coccineum on soils that are rich in total phosphorus, but with a low concentration of available phosphorus.
41 citations
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TL;DR: Analysis of biological samples, including urine, hair and renal tissue, did not provide evidence to support Cd or As toxicity in CKDu patients, and these observations strongly support previous reports on the absence of Cd and Asoxicity in areas with high prevalence of CKDu.
41 citations
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TL;DR: It is suggested that keratinization in oral epithelium plays an important role in the biological function of hBD-2 both at the mRNA level and in the retention of the peptide in the epithelial cells.
Abstract: Human beta-defensin(hBD)-2, an antimicrobial peptide, is produced by various epithelial cells. Because hBD-2 expression in the oral epithelium has not been assessed, we investigated its localization in normal oral epithelium and epithelial lesions. hBD-2 expression was studied using immunohistochemistry and in situ hybridization on formalin-fixed, paraffin-embedded tissue sections from 30 cases of squamous cell carcinoma and 6 cases of leukoplakia. Immunostaining for hBD-2 was more intense in hyperkeratinized than in ortho- or non-keratinized epithelium. In contrast, signals for hBD-2 mRNA were frequently stronger in non-keratinized epithelium than in hyper- or ortho-keratinized epithelium. The results suggest that keratinization in oral epithelium plays an important role in the biological function of hBD-2 both at the mRNA level and in the retention of the peptide in the epithelium.
41 citations
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TL;DR: Hump-nosed pit viper bites result in a mild coagulopathy which is characterised by mild elevation of INR, low fibrinogen and Factors V and VIII which may be consistent with the venom containing a thrombin-like enzyme.
Abstract: Context Limited information exists on the coagulopathy caused by hump-nosed pit viper (Hypnale hypnale) envenoming Objectives This study aimed to characterise the coagulopathy in hump-nosed pit
41 citations
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TL;DR: Urinary KIM-1 was the best early biomarker of kidney injury in this glyphosate-induced nephrotoxicity model and best predicted histological changes at 8h (best cut-off point>0.00029 μg/ml).
41 citations
Authors
Showing all 5992 results
Name | H-index | Papers | Citations |
---|---|---|---|
David Gunnell | 114 | 688 | 79867 |
Michael S. Roberts | 82 | 740 | 27754 |
Richard F. Gillum | 77 | 217 | 84184 |
Lakshman P. Samaranayake | 75 | 586 | 19972 |
Adrian C. Newton | 74 | 453 | 21814 |
Nick Jenkins | 71 | 325 | 22477 |
Michael Eddleston | 63 | 310 | 16762 |
Velmurugu Ravindran | 63 | 280 | 14057 |
Samath D Dharmaratne | 62 | 151 | 103916 |
Nicholas A. Buckley | 62 | 419 | 14283 |
Saman Warnakulasuriya | 60 | 282 | 15766 |
Keith W. Hipel | 58 | 543 | 14045 |
Geoffrey K. Isbister | 57 | 468 | 12690 |
Fiona J Charlson | 53 | 91 | 80274 |
Abbas Shafiee | 51 | 418 | 8679 |