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Institution

University of Peradeniya

EducationKandy, Sri Lanka
About: University of Peradeniya is a education organization based out in Kandy, Sri Lanka. It is known for research contribution in the topics: Population & Poison control. The organization has 5970 authors who have published 7388 publications receiving 197002 citations.


Papers
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Journal ArticleDOI
TL;DR: The research findings on the relationship between antibiotics and oral candidosis and possible mechanisms of pathogenicity following such therapy are discussed.
Abstract: The advent of the human immunodeficiency virus infection and the increasing prevalence of compromised individuals in the community due to modern therapeutic advances have resulted in a resurgence of opportunistic infections, including oral candidosis, which is by far the most common oral fungal infection in man. Broad-spectrum antibiotics used in the treatment of a wide range of disease conditions have also been attributed as a predisposing factor of oral candidosis. In this mini review we discuss the research findings on the relationship between antibiotics and oral candidosis and possible mechanisms of pathogenicity following such therapy.

79 citations

Journal ArticleDOI
TL;DR: In this paper, a curve fitting of adsorption equilibrium data obtained under optimized conditions, followed by error analysis, for different isotherms, namely Langmuir, Freundlich, Temkin, Dubinin-Radushkevich, Redlich-Peterson, and Sips, demonstrates that the Sips models show the best agreement with maximum biosorption capacities (q max) of 145.8 and 150.1 µg−1, respectively, which are superior to most reported biosorbents.
Abstract: Artocarpus altilis (Breadfruit) skin shows great potential as an effective low-cost biosorbent for the removal of toxic crystal violet (CV) dye. Curve fitting of adsorption equilibrium data obtained under optimized conditions, followed by error analysis, for different isotherms, namely Langmuir, Freundlich, Temkin, Dubinin–Radushkevich, Redlich–Peterson, and Sips, demonstrates that the Langmuir and the Sips adsorption isotherm models show the best agreement with maximum biosorption capacities (q max) of 145.8 and 150.1 mg g−1, respectively, which are superior to most reported biosorbents. Breadfruit skin, whose point of zero charge is at pH 4.7, characterized by X-ray fluorescence (XRF) spectroscopy, scanning electron microscopy (SEM) and Fourier transform infra red (FTIR) spectroscopy before and after treatment of CV provides further support for adsorption. Thermodynamic studies indicate that the adsorption of CV by BS was both spontaneous and endothermic, while kinetics studies show that the sorption of CV on BS follows the pseudo-second-order kinetics with a contribution from intraparticle diffusion.

79 citations

Journal ArticleDOI
TL;DR: In overall terms potassium promoted growth of both species when subject to suboptimal soil moisture, and the application of potassium fertilizer can be considered a significant factor in overcoming soil moisture stress in these legumes commonly grown in tropical cropping systems.
Abstract: Tropical food legumes are grown in a wide range of environments, and water stress is considered the principal environmental factor limiting growth and yield. Potassium fertilizer mitigates the impact of water stress in plants. However, the benefits of potassium in overcoming stress in tropical food legumes have not been investigated in comparative studies. The purpose of this study was to determine the benefits of potassium in overcoming water stress in mungbean and cowpea, two important tropical food legumes with different adaptabilities to soil moisture regimes. The experiment carried out under controlled conditions placed emphasis on vegetative growth and selected physiological parameters. The impact of potassium was different in the two legumes grown at optimal and suboptimal soil moisture. Potassium increased shoot growth of mungbean to a greater extent than in cowpea under suboptimal moisture conditions. The roots of cowpea showed a greater response to potassium fertilizer than in mungbean under suboptimal soil moisture. The plant water relations and photosynthetic rates of mungbean were improved to a greater extent by potassium under suboptimal soil moisture than those of cowpea. Although differences were observed in the responses of the vegetative growth of these species to moisture and potassium, in overall terms potassium promoted growth of both species when subject to suboptimal soil moisture. While field studies are required to validate the results, the application of potassium fertilizer can be considered a significant factor in overcoming soil moisture stress in these legumes commonly grown in tropical cropping systems.

79 citations

Journal ArticleDOI
TL;DR: Simultaneous determination of the organophosphorus pesticides dimethoate, fenthion, diazinon and chlorpyrifos in human blood by HPLC-tandem mass spectrometry was developed and validated and displays analytical performance characteristics suitable for the quantification of these pesticides in cases of acute poisoning.

79 citations

Journal ArticleDOI
TL;DR: The seroepidemiologic and clinical characteristics of the leptospirosis outbreak in 2008 in Sri Lanka are described and the urgent need for increasing laboratory diagnostic capabilities to determine the causes of epidemic and endemic infectious diseases in Lanka is strengthened.
Abstract: Global leptospirosis disease burden estimates are hampered by the lack of scientifically sound data from countries with probable high endemicity and limited diagnostic capacities. We describe the seroepidemiologic and clinical characteristics of the leptospirosis outbreak in 2008 in Sri Lanka. Definitive/presumptive case definitions proposed by the World Health Organization Leptospirosis Epidemiology Reference Group were used for case confirmation. Of the 404 possible cases, 155 were confirmed to have leptospirosis. Highest titers of patient seum samples reacted with serovars Pyrogenes (28.7%), Hardjo (18.8%), Javanica (11.5%), and Hebdomadis (11.5%). Sequencing of the 16S ribosomal DNA gene identified six infections: five with Leptospira interrogans and one with L. weilli. In this patient population, acute renal failure was the main complication (14.8%), followed by myocarditis (7.1%) and heart failure (3.9%). The case-fatality rate was 1.3%. This report strengthens the urgent need for increasing laboratory diagnostic capabilities to determine the causes of epidemic and endemic infectious diseases in Sri Lanka, a finding relevant to other tropical regions.

78 citations


Authors

Showing all 5992 results

NameH-indexPapersCitations
David Gunnell11468879867
Michael S. Roberts8274027754
Richard F. Gillum7721784184
Lakshman P. Samaranayake7558619972
Adrian C. Newton7445321814
Nick Jenkins7132522477
Michael Eddleston6331016762
Velmurugu Ravindran6328014057
Samath D Dharmaratne62151103916
Nicholas A. Buckley6241914283
Saman Warnakulasuriya6028215766
Keith W. Hipel5854314045
Geoffrey K. Isbister5746812690
Fiona J Charlson539180274
Abbas Shafiee514188679
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202313
202250
2021648
2020630
2019500
2018539