Institution
University of Perugia
Education•Perugia, Umbria, Italy•
About: University of Perugia is a education organization based out in Perugia, Umbria, Italy. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 13365 authors who have published 39516 publications receiving 1265601 citations. The organization is also known as: Universitá degli Studi di Perugia & Universita degli Studi di Perugia.
Topics: Population, Large Hadron Collider, Immune system, Medicine, Catalysis
Papers published on a yearly basis
Papers
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TL;DR: It is established that FXR ligands might represent a novel therapeutic option to treat liver fibrosis and that SHP binds JunD and inhibits DNA binding of adaptor protein (AP)-1 induced by thrombin.
428 citations
TL;DR: An important feature of GRIND is that, with the use of appropriate software, the original descriptors (molecular interaction fields) can be regenerated from the autocorrelation transform and, thus, the results of the analysis represented graphically, together with the original molecular structures, in 3D plots.
Abstract: Traditional methods for performing 3D-QSAR rely upon an alignment step that is often time-consuming and can introduce user bias, the resultant model being dependent upon and sensitive to the alignment used. There are several methods which overcome this problem, but in general the necessary transformations prevent a simple interpretation of the resultant models in the original descriptor space (i.e. 3D molecular coordinates). Here we present a novel class of molecular descriptors which we have termed GRid-INdependent Descriptors (GRIND). They are derived in such a way as to be highly relevant for describing biological properties of compounds while being alignment-independent, chemically interpretable, and easy to compute. GRIND are obtained starting from a set of molecular interaction fields, computed by the program GRID or by other programs. The procedure for computing the descriptors involves a first step, in which the fields are simplified, and a second step, in which the results are encoded into alignm...
427 citations
TL;DR: In this paper, the authors use the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) to improve and expand the quantification of personal health-care access and quality for 195 countries and territories from 1990 to 2015.
427 citations
TL;DR: The restricted distribution of the CD30 antigen in normal human tissues makes it a potential target for antibody-mediated therapy and prompted construction of anti-CD30 immunotoxins that have recently been clinically used and shown to display antitumor activity against refractory HD.
426 citations
TL;DR: This paper proposes novel channel estimators to combat both the noise and the out-of-band interference in orthogonal frequency-division multiplexing (OFDM) systems.
Abstract: In this paper, we deal with channel estimation for orthogonal frequency-division multiplexing (OFDM) systems. The channels are assumed to be time-varying (TV) and approximated by a basis expansion model (BEM). Due to the time-variation, the resulting channel matrix in the frequency domain is no longer diagonal, but approximately banded. Based on this observation, we propose novel channel estimators to combat both the noise and the out-of-band interference. In addition, the effect of a receiver window on channel estimation is also studied. Our claims are supported by simulation results, which are obtained considering Jakes' channels with fairly high Doppler spreads
426 citations
Authors
Showing all 13488 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Michael Grätzel | 248 | 1423 | 303599 |
| Luigi Ferrucci | 193 | 1601 | 181199 |
| Tobin J. Marks | 159 | 1621 | 111604 |
| Johan Auwerx | 158 | 653 | 95779 |
| Tony Pawson | 150 | 425 | 85196 |
| Jack Hirsh | 146 | 734 | 86332 |
| Alexander Belyaev | 142 | 1895 | 100796 |
| R. L. McCarthy | 141 | 1238 | 115696 |
| Harvey B Newman | 139 | 1594 | 88308 |
| Guido Tonelli | 138 | 1458 | 97248 |
| Elias Campo | 135 | 761 | 85160 |
| Alberto Messineo | 134 | 1511 | 96492 |
| Franco Ligabue | 134 | 1404 | 95389 |
| Roberto Tenchini | 133 | 1390 | 94541 |
| R. Bartoldus | 132 | 1624 | 97405 |