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Institution

University of Pittsburgh

EducationPittsburgh, Pennsylvania, United States
About: University of Pittsburgh is a education organization based out in Pittsburgh, Pennsylvania, United States. It is known for research contribution in the topics: Population & Transplantation. The organization has 87042 authors who have published 201012 publications receiving 9656783 citations. The organization is also known as: Pitt & Western University of Pennsylvania.


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Journal ArticleDOI
TL;DR: The results suggest that while the use of networked communication technologies may alter the form of communication, balancing the opposing impacts of membership size and communication activity in order to maintain resource availability and provide benefits for current members remains a fundamental problem underlying the development of sustainable online social structures.
Abstract: As telecommunication networks become more common, there is an increasing interest in the factors underlying the development of online social structures. It has been proposed that these structures are new forms of organizing which are not subject to the same constraints as traditional social structures. However, from anecdotal evidence and case studies it is difficult to evaluate whether online social structures are subject to the same problems as traditional social structures. Drawing from prior studies of traditional social structures and empirical analyses of longitudinal data from a sample of Internet-based groups, this exploratory work considers the role of size and communication activity in sustainable online social structures.A resource-based theory of sustainable social structures is presented. Members contribute time, energy, and other resources, enabling a social structure to provide benefits for individuals. These benefits, which include information, influence, and social support, are the basis for a social structure's ability to attract and retain members. This model focuses on the system of opposing forces that link membership size as a component of resource availability and communication activity as an aspect of benefit provision to the sustainability of an online social structure. Analyses of data from a random sample of e-mail-based Internet social structures (listservs) indicate that communication activity and size have both positive and negative effects on a structure's sustainability. These results suggest that while the use of networked communication technologies may alter the form of communication, balancing the opposing impacts of membership size and communication activity in order to maintain resource availability and provide benefits for current members remains a fundamental problem underlying the development of sustainable online social structures.

858 citations

Journal ArticleDOI
TL;DR: The odds of substance use for LGB youth were, on average, 190% higher than for heterosexual youth and substantially higher within some subpopulations of LGB young people (340% higher for bisexual youth, 400%Higher for females).
Abstract: Aims Several decades of research have shown that lesbian, gay and bisexual (LGB) adults are at high risk for substance use and substance use disorders (SUDs) These problems may often start prior to young adulthood; however, relatively little is known about risk for substance use in LGB adolescents The primary aims of this paper were to conduct a meta-analysis of the relationship between sexual orientation and adolescent substance use and a systematic review and critique of the methodological characteristics of this literature

858 citations

Journal ArticleDOI
TL;DR: An expert panel in PCOS and CVD reviewed literature and presented recommendations, finding women with PCOS with obesity, cigarette smoking, dyslipidemia, hypertension, impaired glucose tolerance, and subclinical vascular disease are at risk, whereas those with metabolic syndrome and/or type 2 diabetes mellitus are at high risk for CVD.
Abstract: Objective: Women with polycystic ovary syndrome (PCOS) often have cardiovascular disease (CVD) risk factors. The Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society created a panel to provide evidence-based reviews of studies assessing PCOS-CVD risk relationships and to develop guidelines for preventing CVD. Participants: An expert panel in PCOS and CVD reviewed literature and presented recommendations. Evidence: Only studies comparing PCOS with control patients were included. All electronic databases were searched; reviews included individual studies/databases, systematic reviews, abstracts, and expert data. Articles were excluded if other hyperandrogenic disorders were not excluded, PCOS diagnosis was unclear, controls were not described, or methodology precluded evaluation. Inclusion/exclusion criteria were confirmed by at least two reviewers and arbitrated by a third. Consensus Process: Systematic reviews of CVD risk factors were compiled and submitted for approval to the AE-PCOS Society B...

857 citations

Journal ArticleDOI
TL;DR: In this article, the Mini-Cog, a brief cognitive screening test, was used in an epidemiological study of dementia in older Americans, and the results showed that it was as effective in detecting dementia as longer screening and assessment instruments.
Abstract: OBJECTIVES: To test the Mini-Cog, a brief cognitive screening test, in an epidemiological study of dementia in older Americans. DESIGN: A population-based post hoc examination of the sensitivity and specificity of the Mini-Cog for detecting dementia in an existing data set. SETTING: The Monongahela Valley in Western Pennsylvania. PARTICIPANTS: A random sample of 1,119 older adults enrolled in the Monongahela Valley Independent Elders Survey (MoVIES). MEASUREMENTS: The effectiveness of the Mini-Cog in detecting independently diagnosed dementia was compared with that of the Mini-Mental State Examination (MMSE) and a standardized neuropsychological battery. RESULTS: The Mini-Cog, scored by an algorithm as ‘‘possibly impaired’’ or ‘‘probably normal,’’ and the MMSE, at a cutpoint of 25, had similar sensitivity (76% vs 79%) and specificity (89% vs 88%) for dementia, comparable with that achieved using a conventional neuropsychological battery (75% sensitivity, 90% specificity). CONCLUSION: When applied post hoc to an existing population, the Mini-Cog was as effective in detecting dementia as longer screening and assessment instruments. Its brevity is a distinct advantage when the goal is to improve identification of older adults in a population who may be cognitively impaired. Prior evidence of good performance in a multiethnic community-based sample further supports its validity in the ethnolinguistically diverse populations of the United States in which widely used cognitive screens often fail. J Am Geriatr Soc 51:1451–1454, 2003.

856 citations

Journal ArticleDOI
15 Oct 2010-Spine
TL;DR: The Spine Instability Neoplastic Score is a comprehensive classification system with content validity that can guide clinicians in identifying when patients with neoplastic disease of the spine may benefit from surgical consultation and aid surgeons in assessing the key components of spinal instability due to neoplasia.
Abstract: Study design Systematic review and modified Delphi technique. Objective To use an evidence-based medicine process using the best available literature and expert opinion consensus to develop a comprehensive classification system to diagnose neoplastic spinal instability. Summary of background data Spinal instability is poorly defined in the literature and presently there is a lack of guidelines available to aid in defining the degree of spinal instability in the setting of neoplastic spinal disease. The concept of spinal instability remains important in the clinical decision-making process for patients with spine tumors. Methods We have integrated the evidence provided by systematic reviews through a modified Delphi technique to generate a consensus of best evidence and expert opinion to develop a classification system to define neoplastic spinal instability. Results A comprehensive classification system based on patient symptoms and radiographic criteria of the spine was developed to aid in predicting spine stability of neoplastic lesions. The classification system includes global spinal location of the tumor, type and presence of pain, bone lesion quality, spinal alignment, extent of vertebral body collapse, and posterolateral spinal element involvement. Qualitative scores were assigned based on relative importance of particular factors gleaned from the literature and refined by expert consensus. Conclusion The Spine Instability Neoplastic Score is a comprehensive classification system with content validity that can guide clinicians in identifying when patients with neoplastic disease of the spine may benefit from surgical consultation. It can also aid surgeons in assessing the key components of spinal instability due to neoplasia and may become a prognostic tool for surgical decision-making when put in context with other key elements such as neurologic symptoms, extent of disease, prognosis, patient health factors, oncologic subtype, and radiosensitivity of the tumor.

856 citations


Authors

Showing all 87737 results

NameH-indexPapersCitations
JoAnn E. Manson2701819258509
Graham A. Colditz2611542256034
Yi Chen2174342293080
David J. Hunter2131836207050
David Miller2032573204840
Rakesh K. Jain2001467177727
Lewis C. Cantley196748169037
Dennis W. Dickson1911243148488
Terrie E. Moffitt182594150609
Dennis S. Charney179802122408
Ronald C. Petersen1781091153067
David L. Kaplan1771944146082
Jasvinder A. Singh1762382223370
Richard K. Wilson173463260000
Deborah J. Cook173907148928
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023260
20221,089
202111,151
202010,407
20199,333
20188,577