Institution
University of Portsmouth
Education•Portsmouth, Portsmouth, United Kingdom•
About: University of Portsmouth is a education organization based out in Portsmouth, Portsmouth, United Kingdom. It is known for research contribution in the topics: Population & Galaxy. The organization has 5452 authors who have published 14256 publications receiving 424346 citations. The organization is also known as: Portsmouth and Gosport School of Science and Art & Portsmouth and Gosport School of Science and the Arts.
Topics: Population, Galaxy, Redshift, Poison control, Fuzzy logic
Papers published on a yearly basis
Papers
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TL;DR: The results suggest that the entire bacterial recognition system is based around the ligation of CD14 by bacterial components and the recruitment of multiple signalling molecules, such as hsp70, hsp90, CXCR4, GDF5 and TLR4, within the lipid rafts.
Abstract: The plasma membrane of cells is composed of lateral heterogeneities, patches and microdomains. These membrane microdomains or lipid rafts are enriched in glycosphingolipids and cholesterol and have been implicated in cellular processes such as membrane sorting and signal transduction. In this study we investigated the importance of lipid raft formation in the innate immune recognition of bacteria using biochemical and fluorescence imaging techniques. We found that receptor molecules that are implicated in lipopolysaccharide (LPS)-cellular activation, such as CD14, heat shock protein (hsp) 70, 90, Chemokine receptor 4 (CXCR4), growth differentiation factor 5 (GDF5) and Toll-like receptor 4 (TLR4), are present in microdomains following LPS stimulation. Lipid raft integrity is essential for LPS-cellular activation, since raft-disrupting drugs, such as nystatin or MCD, inhibit LPS-induced TNF-alpha secretion. Our results suggest that the entire bacterial recognition system is based around the ligation of CD14 by bacterial components and the recruitment of multiple signalling molecules, such as hsp70, hsp90, CXCR4, GDF5 and TLR4, at the site of CD14-LPS ligation, within the lipid rafts.
609 citations
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TL;DR: The literature dealing with the electrochemical corrosion characteristics of unalloyed copper in aqueous chloride media is examined in this paper, where a wide range of electrode geometries, the importance of the chloride ion and the mass transport of anodic corrosion products on the corrosion behaviour of copper are made clear for both freshly polished and ‘filmed’ surfaces.
609 citations
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Fermilab1, University of Surrey2, Universidade Federal do Rio Grande do Sul3, Carnegie Institution for Science4, Stanford University5, University of Arizona6, University College London7, University of Illinois at Urbana–Champaign8, National Center for Supercomputing Applications9, Space Telescope Science Institute10, University of Pennsylvania11, Institut d'Astrophysique de Paris12, University of Portsmouth13, Texas A&M University14, Technische Universität München15, Ludwig Maximilian University of Munich16, California Institute of Technology17, University of Michigan18, University of Chicago19, Max Planck Society20, Ohio State University21, Australian Astronomical Observatory22, Argonne National Laboratory23, Autonomous University of Barcelona24, Brookhaven National Laboratory25, University of Sussex26, University of Manchester27
TL;DR: In this article, the discovery of eight new Milky Way companions in ~1,800 deg^2 of optical imaging data collected during the first year of the Dark Energy Survey (DES) is reported.
Abstract: We report the discovery of eight new Milky Way companions in ~1,800 deg^2 of optical imaging data collected during the first year of the Dark Energy Survey (DES). Each system is identified as a statistically significant over-density of individual stars consistent with the expected isochrone and luminosity function of an old and metal-poor stellar population. The objects span a wide range of absolute magnitudes (M_V from -2.2 mag to -7.4 mag), physical sizes (10 pc to 170 pc), and heliocentric distances (30 kpc to 330 kpc). Based on the low surface brightnesses, large physical sizes, and/or large Galactocentric distances of these objects, several are likely to be new ultra-faint satellite galaxies of the Milky Way and/or Magellanic Clouds. We introduce a likelihood-based algorithm to search for and characterize stellar over-densities, as well as identify stars with high satellite membership probabilities. We also present completeness estimates for detecting ultra-faint galaxies of varying luminosities, sizes, and heliocentric distances in the first-year DES data.
609 citations
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TL;DR: The data confirm antecedents are common before death, cardiac arrest, and unanticipated ICU admission, and the study shows differences in patterns of primary events, the provision of ICU/HDU beds and resuscitation teams, between the UK and ANZ.
608 citations
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California Institute of Technology1, Tel Aviv University2, University of Maryland, College Park3, Goddard Space Flight Center4, University of Wisconsin–Milwaukee5, Stockholm University6, Princeton University7, Liverpool John Moores University8, National Central University9, Hebrew University of Jerusalem10, University of Sydney11, Australian Research Council12, Indian Institute of Astrophysics13, Indian Institute of Science14, Commonwealth Scientific and Industrial Research Organisation15, University of Colorado Boulder16, Columbia University17, University of Washington18, Indian Institute of Technology Bombay19, Inter-University Centre for Astronomy and Astrophysics20, Lawrence Berkeley National Laboratory21, University of California, Berkeley22, George Washington University23, Texas Tech University24, University College London25, University of Leicester26, Space Telescope Science Institute27, National Radio Astronomy Observatory28, University of Portsmouth29, University of Southampton30, Radboud University Nijmegen31, Tokyo Institute of Technology32, Max Planck Society33, Adler Planetarium34, Northwestern University35, University of Oxford36, Weizmann Institute of Science37, Institute for the Physics and Mathematics of the Universe38, San Diego State University39, University of California, Merced40
TL;DR: It is demonstrated that merging neutron stars are a long-sought production site forging heavy elements by r-process nucleosynthesis, which is dissimilar to classical short gamma-ray bursts with ultrarelativistic jets.
Abstract: Merging neutron stars offer an excellent laboratory for simultaneously studying strong-field gravity and matter in extreme environments. We establish the physical association of an electromagnetic counterpart (EM170817) with gravitational waves (GW170817) detected from merging neutron stars. By synthesizing a panchromatic data set, we demonstrate that merging neutron stars are a long-sought production site forging heavy elements by r-process nucleosynthesis. The weak gamma rays seen in EM170817 are dissimilar to classical short gamma-ray bursts with ultrarelativistic jets. Instead, we suggest that breakout of a wide-angle, mildly relativistic cocoon engulfing the jet explains the low-luminosity gamma rays, the high-luminosity ultraviolet-optical-infrared, and the delayed radio and x-ray emission. We posit that all neutron star mergers may lead to a wide-angle cocoon breakout, sometimes accompanied by a successful jet and sometimes by a choked jet.
579 citations
Authors
Showing all 5624 results
Name | H-index | Papers | Citations |
---|---|---|---|
Robert C. Nichol | 187 | 851 | 162994 |
Gavin Davies | 159 | 2036 | 149835 |
Daniel Thomas | 134 | 846 | 84224 |
Will J. Percival | 129 | 473 | 87752 |
Claudia Maraston | 103 | 362 | 59178 |
I. W. Harry | 98 | 312 | 65338 |
Timothy Clark | 95 | 1137 | 53665 |
Kevin Schawinski | 95 | 376 | 30207 |
Ashley J. Ross | 90 | 248 | 46395 |
Josep Call | 90 | 451 | 34196 |
David A. Wake | 89 | 214 | 46124 |
L. K. Nuttall | 89 | 253 | 54834 |
Stephen Neidle | 89 | 457 | 32417 |
Andrew Lundgren | 88 | 249 | 57347 |
Rita Tojeiro | 87 | 229 | 43140 |