University of Portsmouth

About: University of Portsmouth is a education organization based out in Portsmouth, Portsmouth, United Kingdom. It is known for research contribution in the topics: Population & Galaxy. The organization has 5452 authors who have published 14256 publications receiving 424346 citations. The organization is also known as: Portsmouth and Gosport School of Science and Art & Portsmouth and Gosport School of Science and the Arts.

The Sloan Digital Sky Survey-II Photometry and Supernova IA Light Curves from the 2005 Data

Abstract: We present ugriz light curves for 146 spectroscopically-confirmed or spectroscopically-probable Type Ia supernovae (SNe) from the 2005 season of the Sloan Digital Sky Survey-II Supernova (SN) survey. The light curves have been constructed using a photometric technique that we call scene modeling, which is described in detail here; the major feature is that SN brightnesses are extracted from a stack of images without spatial resampling or convolution of the image data. This procedure produces accurate photometry along with accurate estimates of the statistical uncertainty, and can be used to derive photometry taken with multiple telescopes. We discuss various tests of this technique that demonstrate its capabilities. We also describe the methodology used for the calibration of the photometry, and present calibrated magnitudes and fluxes for all of the spectroscopic SNe Ia from the 2005 season.

Thermoresponsive Surface-Grafted Poly(N−isopropylacrylamide) Copolymers: Effect of Phase Transitions on Protein and Bacterial Attachment

Abstract: The ability of polymers displaying lower critical solution temperatures (LCSTs) to mediate bioadsorptive processes was assessed. Three carboxyl-terminated polymers P1−3 with LCSTs respectively of 20, 32, and 42 °C were prepared by free-radical polymerization of N-isopropylacrylamide with and without comonomers acrylamide and N-tert-butylacrylamide. The polymers were grafted to amine-functionalized glass substrates, and their surface properties were investigated by contact angle goniometry and atomic force microscopy. Increases in water contact angle of up to 24° were observed between 10 and 37 °C for polymers with LCSTs of 20 and 32 °C, whereas no change was apparent for control amine-functional and the LCST 42 °C polymer surfaces over this temperature range. Variations in topography in water were also apparent from atomic force microscopy (AFM) studies for all the polymer grafts but not the amine surfaces over these temperatures. Adsorption of 3H-labeled bovine serum albumin and cytochrome c also increas...

Design and structure of stapled peptides binding to estrogen receptors.

Abstract: Synthetic peptides that specifically bind nuclear hormone receptors offer an alternative approach to small molecules for the modulation of receptor signaling and subsequent gene expression. Here we describe the design of a series of novel stapled peptides that bind the coactivator peptide site of estrogen receptors. Using a number of biophysical techniques, including crystal structure analysis of receptor–stapled peptide complexes, we describe in detail the molecular interactions and demonstrate that all-hydrocarbon staples modulate molecular recognition events. The findings have implications for the design of stapled peptides in general.

A brief history of the Rheic Ocean

Abstract: The Rheic Ocean was one of the most important oceans of the Paleozoic Era. It lay between Laurentia and Gondwana from the Early Ordovician and closed to produce the vast Ouachita-Alleghanian-Variscan orogen during the assembly of Pangea. Rifting began in the Cambrian as a continuation of Neoproterozoic orogenic activity and the ocean opened in the Early Ordovician with the separation of several Neoproterozoic arc terranes from the continental margin of northern Gondwana along the line of a former suture. The rapid rate of ocean opening suggests it was driven by slab pull in the outboard Iapetus Ocean. The ocean reached its greatest width with the closure of Iapetus and the accretion of the peri-Gondwanan arc terranes to Laurentia in the Silurian. Ocean closure began in the Devonian and continued through the Mississippian as Gondwana sutured to Laurussia to form Pangea. The ocean consequently plays a dominant role in the Appalachian-Ouachita orogeny of North America, in the basement geology of southern Europe, and in the Paleozoic sedimentary, structural and tectonothermal record from Middle America to the Middle East. Its closure brought the Paleozoic Era to an end.