Institution
University of Puget Sound
Education•Tacoma, Washington, United States•
About: University of Puget Sound is a education organization based out in Tacoma, Washington, United States. It is known for research contribution in the topics: Occupational therapy & Population. The organization has 1055 authors who have published 1794 publications receiving 36410 citations. The organization is also known as: UPS.
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University of California, Los Angeles1, United States Department of Energy2, University of Paris3, Duke University4, University of Massachusetts Medical School5, University of California, Berkeley6, Centre national de la recherche scientifique7, University of California, San Francisco8, Sun Yat-sen University9, University of Tennessee Health Science Center10, University of Minnesota11, Iowa State University12, Genetic Information Research Institute13, Salk Institute for Biological Studies14, Stanford University15, University of Liège16, University of Nebraska–Lincoln17, University of Cambridge18, Washington University in St. Louis19, University of Córdoba (Spain)20, Kyoto University21, Carnegie Institution for Science22, National Autonomous University of Mexico23, University of Münster24, École Normale Supérieure25, University of Melbourne26, University of Paris-Sud27, University of Mainz28, Scripps Research Institute29, Ohio State University30, University of Chicago31, University of Jena32, University of Arizona33, Louisiana State University34, University of New Brunswick35, University College London36, University of Potsdam37, Delaware Biotechnology Institute38, Boyce Thompson Institute for Plant Research39, Macquarie University40, Oklahoma State University Center for Health Sciences41, İzmir University of Economics42, Academy of Sciences of the Czech Republic43, Charles University in Prague44, St. Edward's University45, University of Puget Sound46, Hokkaido University47, Tsinghua University48, Washington State University49, Appalachian State University50, Marquette University51
TL;DR: Analyses of the Chlamydomonas genome advance the understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella.
Abstract: Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the approximately 120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella.
2,554 citations
TL;DR: It is concluded that an absence of precise definitions and procedures for selection and use of vertebrates as ecological indicators is confounded.
Abstract: Plant and animal species have been used for de- cades as indicators of air and water quality and agricultural and range conditions. Increasingly, vertebrates are used to assess population trends and habitat quality for other spe- cies. In this paper we review the conceptual bases, assump- tions, and published guidelines for selection and use of ver- tebrates as ecological indicators. We conclude that an absence of precise definitions and procedures, confounded
793 citations
TL;DR: The model suggests a research agenda to identify effective programs for a broadened array of problems and disorders, examine ethnicity and culture in relation to intervention adoption and impact, clarify conditions under which programs do and do not work, and make tested interventions accessible and effective in community and practice settings.
Abstract: For decades, empirically tested youth interventions have prevented dysfunction by addressing risk and ameliorated dysfunction through treatment. The authors propose linking prevention and treatment within an integrated model. The model suggests a research agenda: Identify effective programs for a broadened array of problems and disorders, examine ethnicity and culture in relation to intervention adoption and impact, clarify conditions under which programs do and do not work, identify change mechanisms that account for effects, test interventions in real-world contexts, and make tested interventions accessible and effective in community and practice settings. Connecting the science and practice of prevention and treatment will be good for science, for practice, and for children, adolescents, and their families.
532 citations
TL;DR: Elevation of plasma ketone body levels through an oral dose of medium chain triglycerides (MCTs) may improve cognitive functioning in older adults with memory disorders and be associated with greater improvement in paragraph recall with MCT treatment relative to placebo.
412 citations
TL;DR: How the integration of recent genomic developments with ecological, physiological and evolutionary perspectives has contributed to addressing unresolved problems about the role of polyploidy is explored and there is reason to believe that the increasingly integrative approaches discussed here should allow us in the future to make more direct connections between the effects of polyPLoidy on the genome and the responses this condition elicits from the organism living in its natural environment.
Abstract: Polyploidy, the condition of possessing more than two complete genomes in a cell, has intrigued biologists for almost a century. Polyploidy is found in many plants and some animal species and today we know that polyploidy has had a role in the evolution of all angiosperms. Despite its widespread occurrence, the direct effect of polyploidy on evolutionary success of a species is still largely unknown. Over the years many attractive hypotheses have been proposed in an attempt to assign functionality to the increased content of a duplicated genome. Among these hypotheses are the proposal that genome doubling confers distinct advantages to a polyploid and that these advantages allow polyploids to thrive in environments that pose challenges to the polyploid's diploid progenitors. This article revisits these long-standing questions and explores how the integration of recent genomic developments with ecological, physiological and evolutionary perspectives has contributed to addressing unresolved problems about the role of polyploidy. Although unsatisfactory, the current conclusion has to be that despite significant progress, there still isn't enough information to unequivocally answer many unresolved questions about cause and effect of polyploidy on evolutionary success of a species. There is, however, reason to believe that the increasingly integrative approaches discussed here should allow us in the future to make more direct connections between the effects of polyploidy on the genome and the responses this condition elicits from the organism living in its natural environment.
395 citations
Authors
Showing all 1089 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| James Evans | 69 | 659 | 23585 |
| Steven Swanson | 43 | 136 | 7932 |
| Xavier Franch | 40 | 362 | 5368 |
| Daniel M. Johnson | 35 | 133 | 6440 |
| Margo B. Holm | 35 | 121 | 3938 |
| John R. Woodward | 33 | 142 | 4315 |
| Andrew Gardner | 33 | 177 | 4439 |
| Eric Lee | 33 | 72 | 12882 |
| Beverly K. Pierson | 30 | 42 | 2600 |
| Aaron K. Sato | 28 | 94 | 4067 |
| David Chiu | 27 | 139 | 2829 |
| David Magnus | 26 | 136 | 2431 |
| David J. Lewis | 26 | 65 | 2576 |
| Sarah Westcott McCoy | 24 | 75 | 1493 |
| D. Wade Hands | 24 | 134 | 2183 |