scispace - formally typeset
Search or ask a question
Institution

University of Queensland

EducationBrisbane, Queensland, Australia
About: University of Queensland is a education organization based out in Brisbane, Queensland, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 51138 authors who have published 155721 publications receiving 5717659 citations. The organization is also known as: UQ & The University of Queensland.


Papers
More filters
Journal ArticleDOI
David M. Evans1, Spencer Cca.2, J J Pointon3, Zhan Su2, D Harvey3, Grazyna Kochan2, Udo Oppermann4, Alexander T. Dilthey5, Matti Pirinen5, Millicent A. Stone6, L H Appleton3, Loukas Moutsianas2, Stephen Leslie2, T. W. H. Wordsworth3, Tony J. Kenna7, Tugce Karaderi3, Gethin P. Thomas7, Minghong Ward8, Michael H. Weisman9, C. Farrar3, Linda A. Bradbury7, Patrick Danoy7, Robert D. Inman10, Walter P. Maksymowych11, Dafna D. Gladman10, Proton Rahman12, Ann W. Morgan13, Helena Marzo-Ortega13, Paul Bowness3, Karl Gaffney14, Gaston Jsh.15, Malcolm D. Smith15, Jácome Bruges-Armas16, Couto A-R.17, Rosa Sorrentino17, Fabiana Paladini17, Manuel A. R. Ferreira18, Huji Xu19, Yu Liu19, L. Jiang19, Carlos López-Larrea, Roberto Díaz-Peña, Antonio López-Vázquez, Tetyana Zayats5, Céline Bellenguez2, Hannah Blackburn, Jenefer M. Blackwell20, Elvira Bramon21, Suzannah Bumpstead21, Juan P. Casas22, Aiden Corvin23, N. Craddock24, Panagiotis Deloukas21, Serge Dronov21, Audrey Duncanson25, Sarah Edkins21, Colin Freeman26, Matthew W. Gillman21, Emma Gray21, R. Gwilliam21, Naomi Hammond21, Sarah E. Hunt21, Janusz Jankowski, Alagurevathi Jayakumar21, Cordelia Langford21, Jennifer Liddle21, Hugh S. Markus27, Christopher G. Mathew28, O. T. McCann21, Mark I. McCarthy29, Palmer Cna.21, Leena Peltonen21, Robert Plomin28, Simon C. Potter21, Anna Rautanen21, Radhi Ravindrarajah21, Michelle Ricketts21, Nilesh J. Samani30, Stephen Sawcer31, A. Strange26, Richard C. Trembath28, Ananth C. Viswanathan32, Ananth C. Viswanathan33, Matthew Waller21, Paul A. Weston21, Pamela Whittaker21, Sara Widaa21, Nicholas W. Wood, Gil McVean26, John D. Reveille34, B P Wordsworth35, Matthew A. Brown35, Peter Donnelly26 
TL;DR: In this paper, the identification of three variants in the RUNX3, LTBR-TNFRSF1A and IL12B regions convincingly associated with ankylosing spondylitis (P < 5 x 10(-8) in the combined discovery and replication datasets) and a further four loci at PTGER4, TBKBP1, ANTXR2 and CARD9 that show strong association across all their datasets (p < 5x 10(-6) overall, with support in each of the three datasets studied).
Abstract: Ankylosing spondylitis is a common form of inflammatory arthritis predominantly affecting the spine and pelvis that occurs in approximately 5 out of 1,000 adults of European descent. Here we report the identification of three variants in the RUNX3, LTBR-TNFRSF1A and IL12B regions convincingly associated with ankylosing spondylitis (P < 5 x 10(-8) in the combined discovery and replication datasets) and a further four loci at PTGER4, TBKBP1, ANTXR2 and CARD9 that show strong association across all our datasets (P < 5 x 10(-6) overall, with support in each of the three datasets studied). We also show that polymorphisms of ERAP1, which encodes an endoplasmic reticulum aminopeptidase involved in peptide trimming before HLA class I presentation, only affect ankylosing spondylitis risk in HLA-B27-positive individuals. These findings provide strong evidence that HLA-B27 operates in ankylosing spondylitis through a mechanism involving aberrant processing of antigenic peptides.

798 citations

Journal ArticleDOI
TL;DR: An assessment of public health strategies designed to tackle behavioural risk factors for chronic diseases that are closely linked with obesity, including aspects of diet and physical inactivity, in Brazil, China, India, Mexico, Russia, and South Africa is presented.

798 citations

Journal ArticleDOI
08 Sep 2005-Polymer
TL;DR: In this article, the electrical conductivity and linear viscoelastic behavior of polyethylene (PE) multiwalled carbon nanotubes (MWCNTs) with weight fractions ranging from 0.1 to 10 wt% were prepared by melt blending using a mini-twin screw extruder.

796 citations

Journal ArticleDOI
TL;DR: In this paper, the authors conducted genome-wide association studies of three phenotypes: subjective well-being (n = 298,420), depressive symptoms (n= 161,460), and neuroticism(n = 170,911).
Abstract: Very few genetic variants have been associated with depression and neuroticism, likely because of limitations on sample size in previous studies. Subjective well-being, a phenotype that is genetically correlated with both of these traits, has not yet been studied with genome-wide data. We conducted genome-wide association studies of three phenotypes: subjective well-being (n = 298,420), depressive symptoms (n = 161,460), and neuroticism (n = 170,911). We identify 3 variants associated with subjective well-being, 2 variants associated with depressive symptoms, and 11 variants associated with neuroticism, including 2 inversion polymorphisms. The two loci associated with depressive symptoms replicate in an independent depression sample. Joint analyses that exploit the high genetic correlations between the phenotypes (|ρ^| ≈ 0.8) strengthen the overall credibility of the findings and allow us to identify additional variants. Across our phenotypes, loci regulating expression in central nervous system and adrenal or pancreas tissues are strongly enriched for association.

796 citations

Journal ArticleDOI
TL;DR: The authors demonstrate a heterostructured NiFe LDH-NS@DG10 hybrid catalyst by coupling of exfoliated Ni-Fe layered double hydroxide (LDH) nanosheet (NS) and defective graphene (DG).
Abstract: Herein, the authors demonstrate a heterostructured NiFe LDH-NS@DG10 hybrid catalyst by coupling of exfoliated Ni-Fe layered double hydroxide (LDH) nanosheet (NS) and defective graphene (DG). The catalyst has exhibited extremely high electrocatalytic activity for oxygen evolution reaction (OER) in an alkaline solution with an overpotential of 0.21 V at a current density of 10 mA cm-2, which is comparable to the current record (≈0.20 V in Fe-Co-Ni metal-oxide-film system) and superior to all other non-noble metal catalysts. Also, it possesses outstanding kinetics (Tafel slope of 52 mV dec-1) for the reaction. Interestingly, the NiFe LDH-NS@DG10 hybrid has also exhibited the high hydrogen evolution reaction (HER) performance in an alkaline solution (with an overpotential of 115 mV by 2 mg cm-2 loading at a current density of 20 mA cm-2) in contrast to barely HER activity for NiFe LDH-NS itself. As a result, the bifunctional catalyst the authors developed can achieve a current density of 20 mA cm-2 by a voltage of only 1.5 V, which is also a record for the overall water splitting. Density functional theory calculation reveals that the synergetic effects of highly exposed 3d transition metal atoms and carbon defects are essential for the bifunctional activity for OER and HER

794 citations


Authors

Showing all 52145 results

NameH-indexPapersCitations
Graham A. Colditz2611542256034
George Davey Smith2242540248373
David J. Hunter2131836207050
Daniel Levy212933194778
Christopher J L Murray209754310329
Matthew Meyerson194553243726
Luigi Ferrucci1931601181199
Nicholas G. Martin1921770161952
Paul M. Thompson1832271146736
Jie Zhang1784857221720
Alan D. Lopez172863259291
Ian J. Deary1661795114161
Steven N. Blair165879132929
Carlos Bustamante161770106053
David W. Johnson1602714140778
Network Information
Related Institutions (5)
University of Sydney
187.3K papers, 6.1M citations

98% related

University of Melbourne
174.8K papers, 6.3M citations

98% related

University of New South Wales
153.6K papers, 4.8M citations

97% related

University of British Columbia
209.6K papers, 9.2M citations

93% related

National University of Singapore
165.4K papers, 5.4M citations

93% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023507
20221,728
202111,678
202010,832
20199,671
20189,015