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Institution

University of Queensland

EducationBrisbane, Queensland, Australia
About: University of Queensland is a education organization based out in Brisbane, Queensland, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 51138 authors who have published 155721 publications receiving 5717659 citations. The organization is also known as: UQ & The University of Queensland.


Papers
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Journal ArticleDOI
TL;DR: Perinatal depression appears to impose a higher burden on women in low- and middle-income countries and studies in low income countries were especially scarce in this review, demonstrating a need for more epidemiological research in those regions.

731 citations

Journal ArticleDOI
24 Nov 2008-Oncogene
TL;DR: Three potential underlying mechanisms are focused on: the capacity of E-cadherin to regulate β-catenin signaling in the canonical Wnt pathway; its potential to inhibit mitogenic signaling through growth factor receptors and the possible links between cadherins and the molecular determinants of epithelial polarity.
Abstract: It has long been recognized that the cell-cell adhesion receptor, E-cadherin, is an important determinant of tumor progression, serving as a suppressor of invasion and metastasis in many contexts. Yet how the loss of E-cadherin function promotes tumor progression is poorly understood. In this review, we focus on three potential underlying mechanisms: the capacity of E-cadherin to regulate beta-catenin signaling in the canonical Wnt pathway; its potential to inhibit mitogenic signaling through growth factor receptors and the possible links between cadherins and the molecular determinants of epithelial polarity. Each of these potential mechanisms provides insights into the complexity that is likely responsible for the tumor-suppressive action of E-cadherin.

731 citations

Journal ArticleDOI
TL;DR: It is discovered that evidence for the benefits of interacting with nature is geographically biased towards high latitudes and Western societies, potentially contributing to a focus on certain types of settings and benefits.
Abstract: There is mounting empirical evidence that interacting with nature delivers measurable benefits to people. Reviews of this topic have generally focused on a specific type of benefit, been limited to a single discipline, or covered the benefits delivered from a particular type of interaction. Here we construct novel typologies of the settings, interactions and potential benefits of people-nature experiences, and use these to organise an assessment of the benefits of interacting with nature. We discover that evidence for the benefits of interacting with nature is geographically biased towards high latitudes and Western societies, potentially contributing to a focus on certain types of settings and benefits. Social scientists have been the most active researchers in this field. Contributions from ecologists are few in number, perhaps hindering the identification of key ecological features of the natural environment that deliver human benefits. Although many types of benefits have been studied, benefits to physical health, cognitive performance and psychological well-being have received much more attention than the social or spiritual benefits of interacting with nature, despite the potential for important consequences arising from the latter. The evidence for most benefits is correlational, and although there are several experimental studies, little as yet is known about the mechanisms that are important for delivering these benefits. For example, we do not know which characteristics of natural settings (e.g., biodiversity, level of disturbance, proximity, accessibility) are most important for triggering a beneficial interaction, and how these characteristics vary in importance among cultures, geographic regions and socio-economic groups. These are key directions for future research if we are to design landscapes that promote high quality interactions between people and nature in a rapidly urbanising world.

730 citations

Journal ArticleDOI
Lianne Schmaal1, Derrek P. Hibar2, Philipp G. Sämann3, Geoffrey B. Hall4, Bernhard T. Baune5, Neda Jahanshad2, Joshua W. Cheung2, T.G.M. van Erp6, Daniel Bos7, M. A. Ikram7, Meike W. Vernooij7, Wiro J. Niessen7, Wiro J. Niessen8, Henning Tiemeier9, Henning Tiemeier7, A. Hofman7, Katharina Wittfeld10, Hans-Jörgen Grabe10, Hans-Jörgen Grabe11, Deborah Janowitz11, Robin Bülow11, M Selonke11, Henry Völzke11, Dominik Grotegerd12, Udo Dannlowski12, Udo Dannlowski13, Volker Arolt12, Nils Opel12, Walter Heindel12, Harald Kugel12, D. Hoehn3, Michael Czisch3, Baptiste Couvy-Duchesne14, Baptiste Couvy-Duchesne15, Miguel E. Rentería15, Lachlan T. Strike14, Margaret J. Wright14, Natalie T. Mills14, Natalie T. Mills15, G.I. de Zubicaray16, Katie L. McMahon14, Sarah E. Medland15, Nicholas G. Martin15, Nathan A. Gillespie17, Roberto Goya-Maldonado18, Oliver Gruber19, Bernd Krämer19, Sean N. Hatton20, Jim Lagopoulos20, Ian B. Hickie20, Thomas Frodl21, Thomas Frodl22, Angela Carballedo21, Eva-Maria Frey23, L. S. van Velzen1, B.W.J.H. Penninx1, M-J van Tol24, N.J. van der Wee25, Christopher G. Davey26, Ben J. Harrison26, Benson Mwangi27, Bo Cao27, Jair C. Soares27, Ilya M. Veer28, Henrik Walter28, D. Schoepf29, Bartosz Zurowski30, Carsten Konrad13, Elisabeth Schramm31, Claus Normann31, Knut Schnell19, Matthew D. Sacchet32, Ian H. Gotlib32, Glenda MacQueen33, Beata R. Godlewska34, Thomas Nickson35, Andrew M. McIntosh36, Andrew M. McIntosh35, Martina Papmeyer37, Martina Papmeyer35, Heather C. Whalley35, Jeremy Hall35, Jeremy Hall38, J.E. Sussmann35, Meng Li39, Martin Walter40, Martin Walter39, Lyubomir I. Aftanas, Ivan Brack, Nikolay A. Bokhan41, Nikolay A. Bokhan42, Nikolay A. Bokhan43, Paul M. Thompson2, Dick J. Veltman1 
TL;DR: In this article, the authors present the largest ever worldwide study by the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Major Depressive Disorder Working Group on cortical structural alterations in MDD.
Abstract: The neuro-anatomical substrates of major depressive disorder (MDD) are still not well understood, despite many neuroimaging studies over the past few decades. Here we present the largest ever worldwide study by the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Major Depressive Disorder Working Group on cortical structural alterations in MDD. Structural T1-weighted brain magnetic resonance imaging (MRI) scans from 2148 MDD patients and 7957 healthy controls were analysed with harmonized protocols at 20 sites around the world. To detect consistent effects of MDD and its modulators on cortical thickness and surface area estimates derived from MRI, statistical effects from sites were meta-analysed separately for adults and adolescents. Adults with MDD had thinner cortical gray matter than controls in the orbitofrontal cortex (OFC), anterior and posterior cingulate, insula and temporal lobes (Cohen's d effect sizes: -0.10 to -0.14). These effects were most pronounced in first episode and adult-onset patients (>21 years). Compared to matched controls, adolescents with MDD had lower total surface area (but no differences in cortical thickness) and regional reductions in frontal regions (medial OFC and superior frontal gyrus) and primary and higher-order visual, somatosensory and motor areas (d: -0.26 to -0.57). The strongest effects were found in recurrent adolescent patients. This highly powered global effort to identify consistent brain abnormalities showed widespread cortical alterations in MDD patients as compared to controls and suggests that MDD may impact brain structure in a highly dynamic way, with different patterns of alterations at different stages of life.

728 citations

Journal ArticleDOI
01 Jan 1996-Carbon
TL;DR: In this article, the effect of process variables such as carbonization time, temperature, particle size, chemical agents, method of mixing and impregnation ratio in the chemical activation process was studied in order to optimize those preparation parameters.

727 citations


Authors

Showing all 52145 results

NameH-indexPapersCitations
Graham A. Colditz2611542256034
George Davey Smith2242540248373
David J. Hunter2131836207050
Daniel Levy212933194778
Christopher J L Murray209754310329
Matthew Meyerson194553243726
Luigi Ferrucci1931601181199
Nicholas G. Martin1921770161952
Paul M. Thompson1832271146736
Jie Zhang1784857221720
Alan D. Lopez172863259291
Ian J. Deary1661795114161
Steven N. Blair165879132929
Carlos Bustamante161770106053
David W. Johnson1602714140778
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023507
20221,728
202111,678
202010,832
20199,671
20189,015