University of Queensland

About: University of Queensland is a education organization based out in Brisbane, Queensland, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 51138 authors who have published 155721 publications receiving 5717659 citations. The organization is also known as: UQ & The University of Queensland.

Assimilation and Diversity: An Integrative Model of Subgroup Relations:

Abstract: A model of sociostructural relations among subgroups within a superordinate category is presented. Contextualized by discussion of political and social psychological models of intergroup contact, we extend principles of social identity theory to address structural differentiation within groups. Subgroup identity threat plays a pivotal role in the nature of subgroup relations, as do the social realities of specific subgroup relations (i.e., inclusiveness, nested vs. crosscutting categories, leadership, instrumental goal relations, power and status differentials, subgroup similarity). Our analysis suggests that subgroup identity threat is the greatest obstacle to social harmony; social arrangements that threaten social identity produce defensive reactions that result in conflict. Social harmony is best achieved by maintaining, not weakening, subgroup identities, and locating them within the context of a binding superordinate identity.

Physiological plasticity increases resilience of ectothermic animals to climate change

Abstract: Acclimation, a form of physiological plasticity, is the capacity for organisms to physiologically adjust to temperature variation. Such changes can potentially reduce climate change impacts on animal populations. Research synthesizing the current state of knowledge about physiological plasticity in ectotherms shows that freshwater and marine animals seem to have a greater capacity for acclimation than terrestrial ones.

Retroviral intasome assembly and inhibition of DNA strand transfer

Abstract: Integrase is an essential retroviral enzyme that binds both termini of linear viral DNA and inserts them into a host cell chromosome. The structure of full-length retroviral integrase, either separately or in complex with DNA, has been lacking. Furthermore, although clinically useful inhibitors of HIV integrase have been developed, their mechanism of action remains speculative. Here we present a crystal structure of full-length integrase from the prototype foamy virus in complex with its cognate DNA. The structure shows the organization of the retroviral intasome comprising an integrase tetramer tightly associated with a pair of viral DNA ends. All three canonical integrase structural domains are involved in extensive protein–DNA and protein–protein interactions. The binding of strand-transfer inhibitors displaces the reactive viral DNA end from the active site, disarming the viral nucleoprotein complex. Our findings define the structural basis of retroviral DNA integration, and will allow modelling of the HIV-1 intasome to aid in the development of antiretroviral drugs.

Speed breeding is a powerful tool to accelerate crop research and breeding

Abstract: The growing human population and a changing environment have raised significant concern for global food security, with the current improvement rate of several important crops inadequate to meet future demand1. This slow improvement rate is attributed partly to the long generation times of crop plants. Here, we present a method called ‘speed breeding’, which greatly shortens generation time and accelerates breeding and research programmes. Speed breeding can be used to achieve up to 6 generations per year for spring wheat (Triticum aestivum), durum wheat (T. durum), barley (Hordeum vulgare), chickpea (Cicer arietinum) and pea (Pisum sativum), and 4 generations for canola (Brassica napus), instead of 2–3 under normal glasshouse conditions. We demonstrate that speed breeding in fully enclosed, controlled-environment growth chambers can accelerate plant development for research purposes, including phenotyping of adult plant traits, mutant studies and transformation. The use of supplemental lighting in a glasshouse environment allows rapid generation cycling through single seed descent (SSD) and potential for adaptation to larger-scale crop improvement programs. Cost saving through light-emitting diode (LED) supplemental lighting is also outlined. We envisage great potential for integrating speed breeding with other modern crop breeding technologies, including high-throughput genotyping, genome editing and genomic selection, accelerating the rate of crop improvement.