University of Rajasthan

About: University of Rajasthan is a education organization based out in Jaipur, India. It is known for research contribution in the topics: Chemical shift & Derivative (chemistry). The organization has 15058 authors who have published 15733 publications receiving 117400 citations. The organization is also known as: Rajasthan University.

Dynamics of HEV viremia, fecal shedding and its relationship with transaminases and antibody response in patients with sporadic acute hepatitis E.

Abstract: There is paucity of data regarding duration of fecal excretion and viremia on sequential samples from individual patients and its correlation with serum transaminases and antibody responses in patients with acute hepatitis E. This prospective study was undertaken at a tertiary care center in Northern India over 15 months. Only those patients of sporadic acute hepatitis E who were in their first week of illness and followed up weekly for liver function tests, IgM anti HEV antibody and HEV RNA in sera and stool were included. HEV RNA was done by RT - nPCR using two pairs of primers from RdRp region of ORF 1 of the HEV genome. Over a period of 15 months 60 patients met the inclusion criterion and were enrolled for the final analysis. The mean age of the patients was 29.2 ± 8.92 years, there were 39 males. The positivity of IgM anti HEV was 80% at diagnosis and 18.3% at 7th week, HEV RNA 85% at diagnosis and 6.6% at 7th week and fecal RNA 70% at the time of diagnosis and 20% at 4th week. The maximum duration of viremia detected was 42 days and fecal viral shedding was 28 days after the onset of illness. Present study reported HEV RNA positivity in sera after normalization of transaminases. Fecal shedding was not seen beyond normalization of transaminases. However, viremia lasted beyond normalization of transaminases suggesting that liver injury is independent of viral replication.

Breast cancer: Awareness and risk factors in college-going younger age group women in Rajasthan.

Abstract: Objectives To determine awareness about breast cancer and its risk factors. Study design Community based prospective cross sectional analysis. Setting College-going younger age group women of Rajasthan, with women's knowledge about breast cancer, risk factors, treatment, detection and preventive modalities as main outcome measures. Results All the respondents had heard of breast cancer. Awareness about breast mass/lump to be cardinal symptom of breast cancer was true for 65% of respondents. The main early diagnostic modality mammography was known by 19% of respondents while 49% aware about ultrasonography. Some 28% of the women were not aware about self breast examination. Conclusions Women do have knowledge deficits about breast cancer and various related factors.

Seaweed-Derived Nontoxic Functionalized Graphene Sheets as Sustainable Materials for the Efficient Removal of Fluoride from High Fluoride Containing Drinking Water

Abstract: Herein we present a sustainable and cost-effective approach for the preparation of functionalized graphene nanosheets (GNs) directly from seaweed and deep eutectic solvents (DESs). The seaweed granules remained after the recovery of juice from fresh brown seaweed, Sargassum tenerrimum, was utilized as a raw material and DESs generated by the complexation of choline chloride and metal salts were employed as solvent and catalyst for the large scale and facile production of metal oxide functionalized GNs. Moreover considering the biological application of such GNs, where nontoxic nature of substrates is desirable, we have also evaluated the cytotoxicity of the functionalized GNs (Fe3O4/Fe, SnO2/SnO/Sn, or ZnO/Zn-functionalized GNs), and most of them were found to be nontoxic against human lung carcinoma cells (A549). Thereafter, efficiency of these GNs was assessed for the removal of F– from fluoride contaminated groundwater (2.72–6.71 mg L–1) used for drinking purposes. After treatment with GNs, the concent...

Molecular characterization of nitrogen fixing microsymbionts from root nodules of Vachellia ( Acacia ) jacquemontii , a native legume from the Thar Desert of India

Abstract: To describe the structure of nodules of Vachellia (Acacia) jacquemontii, and to characterise the rhizobia that occupy them. Light and electron microscopy were used to analyse nodules. Rhizobia were characterised using their 16S rRNA, housekeeping and symbiosis-related gene sequences. Nodules of V. jacquemontii were typical of all other described mimosoid legumes. All 73 of the isolates were strains of Ensifer, and concatenated phylogenetic analysis of their housekeeping genes (rrs, recA, atpD, glnII and dnaK) suggested that they are novel, forming separate lineages close to E. saheli. The phylogenies of the symbiosis-essential genes nodA and nifH were inconsistent with the housekeeping phylogenies. The nodA sequences of most isolates were close to that of E. arboris HAMBI 1552T, but the nifH gene was found to be related to that of E. kostiensis HAMBI 1489T. All the tested Ensifer strains, except for AJ24, were found to be capable of nodulating other species of Vachellia as well as native Indian Mimosa and Prosopis spp. Stressful conditions caused by the alkaline soil of the Thar Desert have resulted in V. jacquemontii being nodulated by diverse and promiscuous Ensifer species that are capable of nodulating other native members of the tribe Mimoseae.