Institution
University of Rennes
Education•Rennes, France•
About: University of Rennes is a education organization based out in Rennes, France. It is known for research contribution in the topics: Population & Crystal structure. The organization has 18404 authors who have published 40374 publications receiving 995327 citations.
Topics: Population, Crystal structure, Ruthenium, Catalysis, Antenna (radio)
Papers published on a yearly basis
Papers
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TL;DR: In this article, the potential that organometallic architectures consisting of two transition metal centers linked by an organic unsaturated spacer present for the study and development of new molecular wires is discussed.
551 citations
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Rotem Botvinik-Nezer1, Rotem Botvinik-Nezer2, Felix Holzmeister3, Colin F. Camerer4 +217 more•Institutions (78)
TL;DR: The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses.
Abstract: Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses1. The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset2-5. Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed.
551 citations
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TL;DR: Results on real images demonstrate that the proposed adaptation of the nonlocal (NL)-means filter for speckle reduction in ultrasound (US) images is able to preserve accurately edges and structural details of the image.
Abstract: In image processing, restoration is expected to improve the qualitative inspection of the image and the performance of quantitative image analysis techniques. In this paper, an adaptation of the nonlocal (NL)-means filter is proposed for speckle reduction in ultrasound (US) images. Originally developed for additive white Gaussian noise, we propose to use a Bayesian framework to derive a NL-means filter adapted to a relevant ultrasound noise model. Quantitative results on synthetic data show the performances of the proposed method compared to well-established and state-of-the-art methods. Results on real images demonstrate that the proposed method is able to preserve accurately edges and structural details of the image.
547 citations
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TL;DR: In this trial involving patients with septic shock, 90‐day all‐cause mortality was lower among those who received hydrocortisone plus fludrocort isone or with drotrecogin alfa (activated), the combination of the three drugs, or their respective placebos.
Abstract: Background Septic shock is characterized by dysregulation of the host response to infection, with circulatory, cellular, and metabolic abnormalities. We hypothesized that therapy with hydrocortisone plus fludrocortisone or with drotrecogin alfa (activated), which can modulate the host response, would improve the clinical outcomes of patients with septic shock. Methods In this multicenter, double-blind, randomized trial with a 2-by-2 factorial design, we evaluated the effect of hydrocortisone-plus-fludrocortisone therapy, drotrecogin alfa (activated), the combination of the three drugs, or their respective placebos. The primary outcome was 90-day all-cause mortality. Secondary outcomes included mortality at intensive care unit (ICU) discharge and hospital discharge and at day 28 and day 180 and the number of days alive and free of vasopressors, mechanical ventilation, or organ failure. After drotrecogin alfa (activated) was withdrawn from the market, the trial continued with a two-group parallel d...
545 citations
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TL;DR: In this article, the authors present partial results of a series of studies on the granitoids from this region, aiming to understand their role in the building of new continental crust in eastern Asia.
543 citations
Authors
Showing all 18470 results
Name | H-index | Papers | Citations |
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Philippe Froguel | 166 | 820 | 118816 |
Bart Staels | 152 | 824 | 86638 |
Yi Yang | 143 | 2456 | 92268 |
Geoffrey Burnstock | 141 | 1488 | 99525 |
Shahrokh F. Shariat | 118 | 1637 | 58900 |
Lutz Ackermann | 116 | 669 | 45066 |
Douglas R. MacFarlane | 110 | 864 | 54236 |
Elliott H. Lieb | 107 | 512 | 57920 |
Fu-Yuan Wu | 107 | 367 | 42039 |
Didier Sornette | 104 | 1295 | 44157 |
Stefan Hild | 103 | 452 | 68228 |
Pierre I. Karakiewicz | 101 | 1207 | 40072 |
Philippe Dubois | 101 | 1098 | 48086 |
François Bondu | 100 | 440 | 69284 |
Jean-Michel Savéant | 98 | 517 | 33518 |