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Institution

University of Rhode Island

EducationKingston, Rhode Island, United States
About: University of Rhode Island is a education organization based out in Kingston, Rhode Island, United States. It is known for research contribution in the topics: Population & Bay. The organization has 11464 authors who have published 22770 publications receiving 841066 citations. The organization is also known as: URI & Rhode Island College of Agriculture and the Mechanic Arts.


Papers
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Journal ArticleDOI
TL;DR: A novel controlled-release gastric retention system, which consists of a matrix tablet, coated with a permeable membrane, which should be greatly reduced due to tablet's expansion, and due to its disintegration or loss in integrity it should then be expelled out of the stomach at the end of the drug release.
Abstract: Purpose. We report on the development of a novel controlled-release gastric retention system, which consists of a matrix tablet, coated with a permeable membrane. When immersed in simulated gastric fluid, the tablet expands. The tablet remains expanded for eighteen to twenty hours, during which time the drug is released. The tablet then either disintegrates into fragments or loses its integrity.

421 citations

Journal ArticleDOI
TL;DR: In this article, the impact of market price, marketing effort, and stocking quantity on customer demand, supplier prices can serve as a coordination mechanism in a supply chain setting, integrating alternative supplier pricing policies within the newsvendor framework, and how the buyer's risk profile moderates the news-vendor order quantity decision.

420 citations

Journal ArticleDOI
TL;DR: The state of plant transformation is reviewed and innovations needed to enable genome editing in crops are pointed to, including a potential game-changer in crop genetics when plant transformation systems are optimized.
Abstract: Plant transformation has enabled fundamental insights into plant biology and revolutionized commercial agriculture. Unfortunately, for most crops, transformation and regeneration remain arduous even after more than thirty years of technological advances. Genome editing provides new opportunities to enhance crop productivity, but relies on genetic transformation and plant regeneration, which are bottlenecks in the process. Herein we review the state of plant transformation and point to innovations needed to enable genome editing in crops. Plant tissue culture methods need optimization and simplification for efficiency and minimize time in culture. Currently, specialized facilities exist for crop transformation. Single cell and robotic techniques should be developed for high throughput genomic screens. Utilization of plant genes involved in developmental reprogramming, wound response, and/or homologous recombination could boost recovery of transformed plants. Engineering universal Agrobacterium strains and recruitment of other microbes, such as Ensifer or Rhizobium, could facilitate delivery of DNA and proteins into plant cells. Synthetic biology should be employed for de novo design of transformation systems. Genome editing is a potential game-changer in crop genetics when plant transformation systems are optimized.

419 citations

Journal ArticleDOI
TL;DR: The aerobic oxidative coupling of arenes such as benzofuran and N-substituted indoles with benzene and derivatives thereof is described and the reaction is shown to take place in both inter- and intramolecular scenarios.

419 citations

Journal ArticleDOI
TL;DR: In this article, the complexities associated with the coprecipitation of metals in calcite using the behavior of Sr and Mg, which have received the most detailed study, are examined.

419 citations


Authors

Showing all 11569 results

NameH-indexPapersCitations
James M. Tiedje150688102287
Roberto Kolter12031552942
Robert S. Stern12076162834
Michael S. Feld11955251968
William C. Sessa11738352208
Kenneth H. Mayer115135164698
Staffan Kjelleberg11442544414
Kevin C. Jones11474450207
David R. Nelson11061566627
Peter K. Smith10785549174
Peter M. Groffman10645740165
Ming Li103166962672
Victor Nizet10256444193
Anil Kumar99212464825
James O. Prochaska9732073265
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202344
2022161
20211,105
20201,058
2019996
2018888