Institution
University of Rijeka
Education•Rijeka, Croatia•
About: University of Rijeka is a education organization based out in Rijeka, Croatia. It is known for research contribution in the topics: Population & Tourism. The organization has 3471 authors who have published 7993 publications receiving 110386 citations. The organization is also known as: Rijeka University & Sveučilište u Rijeci.
Topics: Population, Tourism, European union, Immune system, Cytotoxic T cell
Papers published on a yearly basis
Papers
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Journal Article•
TL;DR: Results obtained with PAMPA suggest that this assay is not a method of choice for screening of macrolide permeability due to the lack of P-gp efflux pump and/or other transporters potentially involved in macrolides transport.
Abstract: The transport of commercially available macrolide antibiotics erythromycin, clarithromycin, roxithromycin, azithromycin, and telithromycin was studied by PAMPA, a model of passive diffusion, and by two models of active transport, Caco-2 and MDCKII-hMDR1. An involvement of efflux pump P-glycoprotein (P-gp) in macrolide transport was also examined. Generally, in Caco-2 and MDCKII-hMDR1 assays without P-gp inhibition, a significantly lower apparent permeability (P app ) in apical-to-basolateral (AB) than basolateral-to-apical (BA) direction was observed [efflux ratio, P app ratio(BA/AB) > 4.2]. Upon P-gp inhibition, P app (AB) was increased and P app (BA) was decreased. The observed P app values, their efflux ratios, as well as a significant decrease in efflux ratios caused by P-gp inhibition (> 50 %) qualify all tested macrolides as P-gp substrates. Results obtained with PAMPA suggest that this assay is not a method of choice for screening of macrolide permeability due to the lack of P-gp efflux pump and/or other transporters potentially involved in macrolide transport.
31 citations
TL;DR: The aim of this paper is to propose an energy-efficient sensing method for the non-stop cold chain management of table grapes in order to reduce the average energy consumption of WSN devices and improve the operation and transmission efficiency of W SN, and finally strengthen the transparency, traceability and stabilization in non- stop cold chain monitoring.
31 citations
TL;DR: A mouse model of optineurin insufficiency in which the TBK1‐interacting N‐terminus of OptnΔ157 mice was deleted is described, establishing optineURin as a positive regulator TBK 1 via a bipartite interaction between these molecules.
31 citations
23 Aug 2017
TL;DR: In this article, the impact of institutional reforms on economic growth in transition countries (new European Union members) and Croatia, in the case of Slovenia and Croatia was investigated. But the authors focused on the impact on the economic growth of transition countries.
Abstract: The aim of this paper is to research, theoretically and empirically, the impact of institutional reforms on economic growth in transition countries (new European Union members) and Croatia, in the ...
30 citations
TL;DR: In this article, the authors focused on experiment-based characterization and modelling of normalized and quenched and tempered low-alloy steel 42CrMo4 subjected to monotonic and cyclic loading and possibility to determine parameters of more complex models from simple ones.
30 citations
Authors
Showing all 3537 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Igor Rudan | 142 | 658 | 103659 |
| Nikola Godinovic | 138 | 1469 | 100018 |
| Ivica Puljak | 134 | 1436 | 97548 |
| Damir Lelas | 133 | 1354 | 93354 |
| D. Mekterovic | 110 | 449 | 46779 |
| Ulrich H. Koszinowski | 96 | 281 | 27709 |
| Michele Doro | 79 | 437 | 20090 |
| Robert Zivadinov | 73 | 522 | 18636 |
| D. Dominis Prester | 70 | 363 | 16701 |
| Daniel Ferenc | 70 | 225 | 16145 |
| Vladimir Parpura | 64 | 226 | 18050 |
| Stipan Jonjić | 62 | 227 | 19363 |
| Dario Hrupec | 60 | 288 | 13345 |
| Alessandro Laviano | 59 | 298 | 14609 |
| Tomislav Terzić | 58 | 271 | 10699 |