Institution
University of Rijeka
Education•Rijeka, Croatia•
About: University of Rijeka is a education organization based out in Rijeka, Croatia. It is known for research contribution in the topics: Population & Tourism. The organization has 3471 authors who have published 7993 publications receiving 110386 citations. The organization is also known as: Rijeka University & Sveučilište u Rijeci.
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TL;DR: Results of this study put forward compound 6 as a potential novel antitumor agent (IMPDH inhibitor) for treating leukaemia because of its significant biological activity and low toxicity in human diploid fibroblasts, encourage further development of this compound as a lead.
83 citations
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TL;DR: An enhanced model of nonlocal torsion based on the Eringen theory is provided in this article, where the variational formulation is given and then the governing differential equation and boundary conditions of non-local nanobeams subjected to torsional loading are consistently derived.
Abstract: An enhanced model of nonlocal torsion based on the Eringen theory is provided in this paper. The variational formulation is given and then the governing differential equation and boundary conditions of nonlocal nanobeams subjected to torsional loading are consistently derived. No higher-order boundary conditions are required for the enhanced model. It is assumed that the ends of nanobeams are not perfectly restrained thus focusing the attention also on the influence of elastically compliant boundary conditions on the behaviour of nonlocal models. Closed-form solutions are then provided for nanocantilevers and fully clamped nanobeams subject to distributed torsional loads. It is shown that the dimensionless small-scale parameter must fulfil a suitable inequality in order to avoid that a positive distributed torsional load provides a negative torsional rotation. The size-dependent static torsional behaviour of the proposed model in terms of torsional rotations and moments is tested. Contrary to the nonlocal Eringen model, the proposed enhanced model provides the small-scale effect also for nanobeams subjected to uniformly distributed torsional loads. Comparisons with Eringen model, gradient elasticity theory and classical (local) model are provided.
83 citations
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TL;DR: The results of the study indicate that the use of autologous and microfragmented adipose tissue in patients with knee OA increased glycosaminoglycan (GAG) content in hyaline cartilage, which is in line with observed VAS and clinical results.
Abstract: Osteoarthritis (OA) is one of the leading musculoskeletal disorders in the adult population. It is associated with cartilage damage triggered by the deterioration of the extracellular matrix tissue. The present study explores the effect of intra-articular injection of autologous microfragmented adipose tissue to host chondrocytes and cartilage proteoglycans in patients with knee OA. A prospective, non-randomized, interventional, single-center, open-label clinical trial was conducted from January 2016 to April 2017. A total of 17 patients were enrolled in the study, and 32 knees with osteoarthritis were assessed. Surgical intervention (lipoaspiration) followed by tissue processing and intra-articular injection of the final microfragmented adipose tissue product into the affected knee(s) was performed in all patients. Patients were assessed for visual analogue scale (VAS), delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) and immunoglobulin G (IgG) glycans at the baseline, three, six and 12 months after the treatment. Magnetic resonance sequence in dGEMRIC due to infiltration of the anionic, negatively charged contrast gadopentetate dimeglumine (Gd-DTPA2-) into the cartilage indicated that the contents of cartilage glycosaminoglycans significantly increased in specific areas of the treated knee joint. In addition, dGEMRIC consequently reflected subsequent changes in the mechanical axis of the lower extremities. The results of our study indicate that the use of autologous and microfragmented adipose tissue in patients with knee OA (measured by dGEMRIC MRI) increased glycosaminoglycan (GAG) content in hyaline cartilage, which is in line with observed VAS and clinical results.
83 citations
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TL;DR: It is indicated that restriction of usage of some antibacterial agents is a successful method to decrease antibiotic consumption and a way to bring cost savings and helps prevent emergence of resistant microorganisms in hospitals.
Abstract: Objective: Antibiotic formulary restrictions are among the most popular methods to control antibiotic utilization in hospitals. The aim of the present survey was to investigate the influence of “reserve antibiotic” on antimicrobial utilization at the University Hospital Center (UHC) Rijeka.
83 citations
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University of Amsterdam1, Moscow State University of Medicine and Dentistry2, University of Rijeka3, University of Ljubljana4, Southmead Hospital5, Generalitat of Catalonia6, Helsinki University Central Hospital7, Carol Davila University of Medicine and Pharmacy8, Meir Medical Center9, University of Copenhagen10, Nicosia General Hospital11, Tbilisi State Medical University12, Charles University in Prague13, Organización Nacional de Trasplantes14, University of Tartu15, RMIT University16, University of Sarajevo17, Slovak Medical University18, Akdeniz University19, Oslo University Hospital20, Sofia Medical University21, Hospital of Lithuanian University of Health Sciences Kaunas Clinics22, French Institute of Health and Medical Research23, University of Würzburg24
TL;DR: The incidence of patients starting RRT pmp secondary to DM in Europe was five times lower and the incidence of RRT due to other causes of ESRD was two times lower than the USA, when compared with the USA.
Abstract: Background
This article provides a summary of the 2013 European Renal Association–European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report (available at http://www.era-edta-reg.org), with a focus on patients with diabetes mellitus (DM) as the cause of end-stage renal disease (ESRD).
83 citations
Authors
Showing all 3537 results
Name | H-index | Papers | Citations |
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Igor Rudan | 142 | 658 | 103659 |
Nikola Godinovic | 138 | 1469 | 100018 |
Ivica Puljak | 134 | 1436 | 97548 |
Damir Lelas | 133 | 1354 | 93354 |
D. Mekterovic | 110 | 449 | 46779 |
Ulrich H. Koszinowski | 96 | 281 | 27709 |
Michele Doro | 79 | 437 | 20090 |
Robert Zivadinov | 73 | 522 | 18636 |
D. Dominis Prester | 70 | 363 | 16701 |
Daniel Ferenc | 70 | 225 | 16145 |
Vladimir Parpura | 64 | 226 | 18050 |
Stipan Jonjić | 62 | 227 | 19363 |
Dario Hrupec | 60 | 288 | 13345 |
Alessandro Laviano | 59 | 298 | 14609 |
Tomislav Terzić | 58 | 271 | 10699 |