Institution
University of Rochester
Education•Rochester, New York, United States•
About: University of Rochester is a education organization based out in Rochester, New York, United States. It is known for research contribution in the topics: Population & Laser. The organization has 63915 authors who have published 112762 publications receiving 5484122 citations. The organization is also known as: Rochester University.
Topics: Population, Laser, Poison control, Health care, Context (language use)
Papers published on a yearly basis
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TL;DR: In this article, the authors identify three methodological shortcomings of the classic Princeton trilogy studies: ambiguity of the instructions given to respondents, no assessment of respondents' level of prejudice, and use of an outdated list of adjectives.
Abstract: In this article, the authors identify three methodological short-comings of the classic Princeton trilogy studies: (a) ambiguity of the instructions given to respondents, (b) no assessment of respondents' level of prejudice, and (c) use of an outdated list of adjectives. These shortcomings are addressed in the authors' assessment of the stereotype and personal beliefs of a sample of University of Wisconsin students. In contrast to the commonly espoused fading stereotype proposition, data suggest that there exists a consistent and negative contemporary stereotype of Blacks. Comparing the data from the Princeton trilogy studies with those of the present study, the authors conclude that the Princeton trilogy studies actually measured respondents' personal beliefs, not (as typically assumed) their knowledge of the Black stereotype. Consistent with Devine's model, high- and low-prejudiced individuals did not differ in their knowledge of the stereotype of Blacks but diverged sharply in their endorsement of the ...
816 citations
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TL;DR: Liraglutide combined with metformin and a thiazolidinedione is a well-tolerated combination therapy for type 2 diabetes, providing significant improvements in glycemic control and C-peptide and homeostasis model assessment of β-cell function.
Abstract: OBJECTIVE To determine the efficacy and safety of liraglutide (a glucagon-like peptide-1 receptor agonist) when added to metformin and rosiglitazone in type 2 diabetes.
RESEARCH DESIGN AND METHODS This 26-week, double-blind, placebo-controlled, parallel-group trial randomized 533 subjects (1:1:1) to once-daily liraglutide (1.2 or 1.8 mg) or liraglutide placebo in combination with metformin (1 g twice daily) and rosiglitazone (4 mg twice daily). Subjects had type 2 diabetes, A1C 7–11% (previous oral antidiabetes drug [OAD] monotherapy ≥3 months) or 7–10% (previous OAD combination therapy ≥3 months), and BMI ≤45 kg/m2.
RESULTS Mean A1C values decreased significantly more in the liraglutide groups versus placebo (mean ± SE −1.5 ± 0.1% for both 1.2 and 1.8 mg liraglutide and −0.5 ± 0.1% for placebo). Fasting plasma glucose decreased by 40, 44, and 8 mg/dl for 1.2 and 1.8 mg and placebo, respectively, and 90-min postprandial glucose decreased by 47, 49, and 14 mg/dl, respectively ( P < 0.001 for all liraglutide groups vs. placebo). Dose-dependent weight loss occurred with 1.2 and 1.8 mg liraglutide (1.0 ± 0.3 and 2.0 ± 0.3 kg, respectively) ( P < 0.0001) compared with weight gain with placebo (0.6 ± 0.3 kg). Systolic blood pressure decreased by 6.7, 5.6, and 1.1 mmHg with 1.2 and 1.8 mg liraglutide and placebo, respectively. Significant increases in C-peptide and homeostasis model assessment of β-cell function and significant decreases in the proinsulin-to-insulin ratio occurred with liraglutide versus placebo. Minor hypoglycemia occurred more frequently with liraglutide, but there was no major hypoglycemia. Gastrointestinal adverse events were more common with liraglutide, but most occurred early and were transient.
CONCLUSIONS Liraglutide combined with metformin and a thiazolidinedione is a well-tolerated combination therapy for type 2 diabetes, providing significant improvements in glycemic control.
815 citations
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TL;DR: In this paper, the dynamics of complex isothermal reactors are studied in general terms with special focus on connections between reaction network structure and the capacity of the corresponding differential equations to admit unstable behavior.
814 citations
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TL;DR: In this paper, the authors examined the relationship between undergraduates' perceptions of their classroom environment, their adoption of achievement goals for the course, and their graded performance and intrinsic motivation, and found that the influence of the perceived classroom environment on these outcomes measures was indirect; the perception of the classroom environment influenced achievement goal adoption, in turn, directly influenced graded performance.
Abstract: Two studies examined the relationship between undergraduates' perceptions of their classroom environment, their adoption of achievement goals for the course, and their graded performance and intrinsic motivation. Results revealed a distinct antecedent profile for each goal in the trichotomous framework: Mastery goals were linked to the presence of lecture engagement and the absence of an evaluation focus and harsh evaluation, performance-approach goals were linked to the presence of evaluation focus, and performance-avoidance goals were linked to the presence of evaluation focus and harsh evaluation. When the perceived classroom environment and achievement goal variables were tested together as predictors of graded performance and intrinsic motivation, the results clearly demonstrated that the influence of the perceived classroom environment on these outcomes measures was indirect; the perceived classroom environment influenced achievement goal adoption, and achievement goal adoption, in turn, directly influenced graded performance and intrinsic motivation.
814 citations
Authors
Showing all 64186 results
Name | H-index | Papers | Citations |
---|---|---|---|
Eugene Braunwald | 230 | 1711 | 264576 |
Cyrus Cooper | 204 | 1869 | 206782 |
Eric J. Topol | 193 | 1373 | 151025 |
Dennis W. Dickson | 191 | 1243 | 148488 |
Scott M. Grundy | 187 | 841 | 231821 |
John C. Morris | 183 | 1441 | 168413 |
Ronald C. Petersen | 178 | 1091 | 153067 |
David R. Williams | 178 | 2034 | 138789 |
John Hardy | 177 | 1178 | 171694 |
Russel J. Reiter | 169 | 1646 | 121010 |
Michael Snyder | 169 | 840 | 130225 |
Jiawei Han | 168 | 1233 | 143427 |
Gang Chen | 167 | 3372 | 149819 |
Marc A. Pfeffer | 166 | 765 | 133043 |
Salvador Moncada | 164 | 495 | 138030 |