University of Rochester

About: University of Rochester is a education organization based out in Rochester, New York, United States. It is known for research contribution in the topics: Population & Laser. The organization has 63915 authors who have published 112762 publications receiving 5484122 citations. The organization is also known as: Rochester University.

Is the incidence of rheumatoid arthritis rising?: Results from Olmsted County, Minnesota, 1955-2007

Abstract: Objective To examine the trends in incidence and prevalence of rheumatoid arthritis (RA) from 1995 to 2007.

Treatment of neural injury with marrow stromal cells

Abstract: Summary We describe our preclinical studies on the use of bone-marrow stromal cells (MSC; an uncharacterised mixed population of plastic-adherent cells) in the treatment of neural injury. These cells obtained from donor rats or human beings have been directly transplanted into brain or administered intra-arterially or intravenously. MSC selectively target injured tissue and promote functional recovery. Signals that target inflammatory cells to injured tissue probably direct MSC to injury sites. Although some MSC express proteins typical of neural cells, the possibility that benefit is derived by replacement of infarcted tissue with differentiated MSC is highly unlikely. MSC activate endogenous restorative responses in injured brain, which include angiogenesis, neurogenesis, and synaptogenesis. Given the robust therapeutic benefit of these cells in the treatment of experimental neural injury, and the fact that MSC have been used in the treatment of other human disease, there is justification for further preclinical studies leading to clinical trials for the treatment of neural injury such as stroke.

Practice parameter: Electrodiagnostic studies in carpal tunnel syndrome: Report of the American Association of Electrodiagnostic Medicine, American Academy of Neurology, and the American Academy of Physical Medicine and Rehabilitation

Abstract: Carpal tunnel syndrome (CTS) is a common clinical problem and frequently requires surgical therapy. The results of electrodiagnostic (EDX) studies have been found to be highly sensitive and specific for the diagnosis of CTS. This document defines the standards, guidelines, and options for EDX studies of CTS based on a critical review of the literature published in 19931 and recently updated by a review of the literature through the year 2000.2 The reader is referred to the updated review2 for a detailed discussion of the literature and the EDX techniques for the assessment of CTS that are summarized here. Both reviews addressed the following key clinical questions: 1. In patients clinically suspected of having CTS, what are the best EDX studies to confirm the diagnosis? 2. How can future clinical research studies be improved to evaluate the usefulness of laboratory studies, including EDX studies, to confirm the diagnosis of CTS? The source of the articles for the first CTS Literature Review1 published in 1993 was a Medline search for literature in English from January 1, 1986 through May 1991. The Medical Subject Headings searched were 1) wrist injuries or wrist joint, 2) nerve compression syndrome, and 3) carpal tunnel syndrome. The search identified 488 articles. Based on a review of the abstracts, 81 articles describing EDX studies were chosen for this review. An additional 78 reports were identified from the bibliographies of these 81 articles and American Academy of Electrodiagnostic Medicine (AAEM) consultants recommended six others. Of the total of 165 articles reviewed, 20 were classified as background references. The source of the articles for the second CTS Literature Review2 was a Medline search for literature in English through December 2000. The Medical Subject Headings (MeSH) searched were 1) carpal tunnel syndrome and diagnosis or 2) carpal …