Institution
University of Rochester
Education•Rochester, New York, United States•
About: University of Rochester is a education organization based out in Rochester, New York, United States. It is known for research contribution in the topics: Population & Laser. The organization has 63915 authors who have published 112762 publications receiving 5484122 citations. The organization is also known as: Rochester University.
Topics: Population, Laser, Poison control, Health care, Large Hadron Collider
Papers published on a yearly basis
Papers
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TL;DR: An overview of the historical links between the emotions and psychopathology is presented in this article, with a focus on the role and development of the emotions in atypical populations and the contributions that the emotions have made for enhancing our understanding of psychopathology have been evident throughout history.
Abstract: The understanding of emotions possesses important implications for elucidating normal as well as abnormal development. The contributions that the emotions have made for enhancing our understanding of psychopathology have been evident throughout history. In this article, an overview of the historical links between the emotions and psychopathology is presented. Despite its rich history, much contemporary theory and research on emotions has been conducted primarily within a nonpathology perspective. In recent decades, investigators have become more interested in examining the role and development of the emotions in atypical populations. It has been argued that the modularity of the emotions system requires a developmental model of emotion regulation.
633 citations
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13 Apr 2004
632 citations
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TL;DR: Proteins pathogenic in Alzheimer's disease were extracted from neurally derived blood exosomes and quantified to develop biomarkers for the staging of sporadic AD.
Abstract: Background Proteins pathogenic in Alzheimer's disease (AD) were extracted from neurally derived blood exosomes and quantified to develop biomarkers for the staging of sporadic AD. Methods Blood exosomes obtained at one time-point from patients with AD (n = 57) or frontotemporal dementia (FTD) (n = 16), and at two time-points from others (n = 24) when cognitively normal and 1 to 10 years later when diagnosed with AD were enriched for neural sources by immunoabsorption. AD-pathogenic exosomal proteins were extracted and quantified by enzyme-linked immunosorbent assays. Results Mean exosomal levels of total tau, P-T181-tau, P-S396-tau, and amyloid β 1–42 (Aβ1–42) for AD and levels of P-T181-tau and Aβ1–42 for FTD were significantly higher than for case-controls. Step-wise discriminant modeling incorporated P-T181-tau, P-S396-tau, and Aβ1–42 in AD, but only P-T181-tau in FTD. Classification of 96.4% of AD patients and 87.5% of FTD patients was correct. In 24 AD patients, exosomal levels of P-S396-tau, P-T181-tau, and Aβ1–42 were significantly higher than for controls both 1 to 10 years before and when diagnosed with AD. Conclusions Levels of P-S396-tau, P-T181-tau, and Aβ1–42 in extracts of neurally derived blood exosomes predict the development of AD up to 10 years before clinical onset.
632 citations
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TL;DR: In this paper, the proposition that autonomy support has a positive effect on self-motivation and well-being was examined in two distinct cultural settings, including Russian adolescents and U.S. students.
Abstract: The proposition, derived from self-determination theory (SDT), that autonomy-support has a positive effect on self-motivation and well-being, is examined in two distinct cultural settings. Participants were 264 high school students from Russia and the United States who completed measures of perceived parental- and teacher-autonomy-support, academic motivation, and well-being. Means and covariance structure analyses were used to examine the cultural comparability of measured constructs. Results supported the hypotheses that Russian adolescents would perceive parents and teachers as more controlling than U.S. students; and in both samples, perceived autonomy-support would predict greater academic self-motivation and well-being. Results are discussed in terms of SDT’s postulate of a basic human need for autonomy in the context of cultural variations.
632 citations
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TL;DR: In this paper, the role of mindfulness on appraisals of and coping with stress experiences in college students and the consequences of such stress processing for well-being are discussed. But, the results of these studies were limited to four studies (n = 65 − 141).
632 citations
Authors
Showing all 64186 results
Name | H-index | Papers | Citations |
---|---|---|---|
Eugene Braunwald | 230 | 1711 | 264576 |
Cyrus Cooper | 204 | 1869 | 206782 |
Eric J. Topol | 193 | 1373 | 151025 |
Dennis W. Dickson | 191 | 1243 | 148488 |
Scott M. Grundy | 187 | 841 | 231821 |
John C. Morris | 183 | 1441 | 168413 |
Ronald C. Petersen | 178 | 1091 | 153067 |
David R. Williams | 178 | 2034 | 138789 |
John Hardy | 177 | 1178 | 171694 |
Russel J. Reiter | 169 | 1646 | 121010 |
Michael Snyder | 169 | 840 | 130225 |
Jiawei Han | 168 | 1233 | 143427 |
Gang Chen | 167 | 3372 | 149819 |
Marc A. Pfeffer | 166 | 765 | 133043 |
Salvador Moncada | 164 | 495 | 138030 |