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Institution

University of Salford

EducationSalford, Manchester, United Kingdom
About: University of Salford is a education organization based out in Salford, Manchester, United Kingdom. It is known for research contribution in the topics: Population & Thin film. The organization has 13049 authors who have published 22957 publications receiving 537330 citations. The organization is also known as: University of Salford Manchester & The University of Salford Manchester.


Papers
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Journal ArticleDOI
TL;DR: The differential expression of ERα, ERβ and AR in human skin suggests that the mechanisms by which steroid hormones mediate their effects may be more complex than previously thought and provides further evidence for oestrogen action in non‐classic target tissues.
Abstract: Oestrogens play a major role in non-classic target tissues in both sexes, yet there have been few studies on estrogens and skin. Recently a second oestrogen receptor (ERbeta) has been discovered. Therefore, we have compared the expression of oestrogen receptor alpha (ERalpha), beta (ERbeta), the androgen receptor (AR) and a cell proliferation marker in male and female non-balding scalp skin. ERbeta was the major steroid receptor expressed in human skin. It was highly expressed in epidermis, blood vessels and dermal fibroblasts, in contrast to ERalpha and AR. In the hair follicle, ERbeta expression was localized to nuclei of outer root sheath, epithelial matrix and dermal papilla cells, in contrast to ERalpha, and the AR, which was only expressed in dermal papilla cells. Serial sections also showed strong nuclear expression of ERbeta in the cells of the bulge, while neither ERalpha nor AR was expressed. In the sebaceous gland, ERbeta was expressed in both basal and partially differentiated sebocytes. ERalpha exhibited a similar pattern of expression, while the AR was expressed in the basal and very early differentiated sebocytes. There was no obvious difference in the expression of either oestrogen receptor in male or female skin. The wide distribution of ERbeta in human skin suggests that oestrogens may play an important role in the maintenance of skin and in the regulation of the pilosebaceous unit, and provides further evidence for oestrogen action in non-classic target tissues. The differential expression of ERalpha, ERbeta and AR in human skin suggests that the mechanisms by which steroid hormones mediate their effects may be more complex than previously thought.

137 citations

Journal ArticleDOI
TL;DR: MRI changes, compatible with a disturbance in the water content of white matter, were present in all but 1 patient and the severity of abnormality was most strongly associated with the blood phenylalanine concentration at the time of imaging.

137 citations

Journal ArticleDOI
Wu Jian1
TL;DR: In this article, the second-order coherent properties of Gaussian-Schell beams propagating through turbulent media as described by the Kolmogorov turbulence model are studied and some theoretical results are presented.
Abstract: The second-order coherent properties of Gaussian-Schell beams propagating through turbulent media as described by the Kolmogorov turbulence model are studied and some theoretical results are presented in this paper.

136 citations

Journal ArticleDOI
TL;DR: Empirical research carried out indicates that facilities management appears to utilise a wide range of measures – not only traditional financial accounting measures, but also indicators of managerial behaviour as well as various other measures of effectiveness.
Abstract: This paper concerns the measurement of facilities management performance. Empirical research carried out indicates that facilities management appears to utilise a wide range of measures – not only traditional financial accounting measures, but also indicators of managerial behaviour as well as various other measures of effectiveness. Considers the basis for measurement of performance in facilities management with reference to a conceptual framework identified by taking into consideration the advantages and some of the drawbacks with current performance measurement systems.

136 citations

Journal ArticleDOI
TL;DR: In this article, the authors describe the design and testing of a gripper developed for the handling of delicate sliced fruit and vegetable products commonly found in the food industry, which operates on the Bernoulli principle whereby air flow over the surface of an object generates a lift.
Abstract: This paper describes the design and testing of a gripper developed for the handling of delicate sliced fruit and vegetable products commonly found in the food industry. The device operates on the Bernoulli principle whereby air flow over the surface of an object generates a lift. The gripper allows objects to be lifted with minimal contact thereby reducing the chances of damaging or contaminating the object. The paper will describe the mathematical basis of the gripper operation followed by tests showing the nature of the grasp. As a secondary benefit it will be shown that the flow of air over the object can also be used to remove surface moisture produced during slicing. This drying effect is a feature particularly useful in some areas of food production. The paper will show a test manufacturing cell demonstrating the placement of slices of tomatoes and cucumber on to sandwiches.

136 citations


Authors

Showing all 13134 results

NameH-indexPapersCitations
Hongjie Dai197570182579
Michael P. Lisanti15163185150
Matthew Jones125116196909
David W. Denning11373666604
Wayne Hall111126075606
Richard Gray10980878580
Christopher E.M. Griffiths10867147675
Thomas P. Davis10772441495
Nicholas Tarrier9232625881
David M. A. Mann8833843292
Ajith Abraham86111331834
Federica Sotgia8524728751
Mike Hulme8430035436
Robert N. Foley8426031580
Richard Baker8351422970
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202331
2022139
2021880
2020888
2019842
2018781