University of Salford

About: University of Salford is a education organization based out in Salford, Manchester, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 13049 authors who have published 22957 publications receiving 537330 citations. The organization is also known as: University of Salford Manchester & The University of Salford Manchester.

System dynamics applications to European health care issues

Abstract: Taking a European perspective, a review is made of some system dynamics models which address health care issues. Suggestions are made for the types of role which these models should take, bearing in mind the strategic orientation of system dynamics modelling. Examples are described of qualitative models where influence diagrams are the main analytical tool. Quantitative system dynamics models have a contribution to make in epidemiological studies and have been used to analyse the AIDS epidemic. A detailed example of one aspect of model formulation is given. This concerns the AIDS incubation time distribution and shows how real-world complications arising from virological staging and treatment effects are handled in a model of AIDS spread.

Evidence for the Role of Psychological Factors in Abnormal Paraspinal Activity in Patients with Chronic Low Back Pain

Abstract: Objectives: The aim of this study was to investigate the role of physical and psychological factors on changes in surface electromyography [sEMG] during static and dynamic activity of the lumbar pa...

The ilizarov method in nonunion, malunion and infection of fractures

Abstract: We have reviewed a series of 56 consecutive patients treated by the Ilizarov circular fixator for various combinations of nonunion, malunion and infection of fractures. We used segmental excision, distraction osteogenesis and gradual correction of the deformity as appropriate. Treatment was effective in eliminating 40 out of 46 nonunions and all 22 infections. There were two cases of refracture some months after removal of the frame, both of which healed securely in a second frame. Correction of malunion was good in the coronal plane but there was a tendency to anterior angulation, often occurring in the regenerate bone rather than at the original fracture site, after removal of the frame. This was associated with very slow maturation of regenerate bone in some patients, occurring largely, but not exclusively, in those who smoked heavily. Patients expressed high levels of satisfaction with the outcome, despite relatively modest improvements in pain and function, presumably because their longstanding and intractable nonunion had been treated. None the less, the degree of satisfaction correlated strongly with the degree of improvement in pain and function. We emphasise the importance of a multidisciplinary team in the assessment and support of patients undergoing long and demanding treatment. The Ilizarov method is valuable, but research is needed to overcome the problems of delayed maturation of the regenerate and slow or insecure healing of the docking site.

Normal human endometrium in cell culture. I. Separation and characterization of epithelial and stromal components in vitro.

Abstract: Separation of human endometrium into its epithelial and stromal components has been achieved through collagenase digestion and has permitted a study of these two cell populations under specific experimental culture conditions The stromal cell populations showed a progesterone response, were easily handled in culture, and displayed a limited in vitro life span typical of human diploid fibroblasts In contrast, epithelium only survived in short-term primary culture and showed no clear hormone response High-density epithelial cultures remained viable for longer periods in culture Comparisons between resurfacing endometrial epithelial cells in vivo and epithelial cells migrating from explants in vitro suggested that this initial epithelial migration in vitro was the counterpart of the repair response in vivo