Institution
University of Salford
Education•Salford, Manchester, United Kingdom•
About: University of Salford is a education organization based out in Salford, Manchester, United Kingdom. It is known for research contribution in the topics: Population & Thin film. The organization has 13049 authors who have published 22957 publications receiving 537330 citations. The organization is also known as: University of Salford Manchester & The University of Salford Manchester.
Topics: Population, Thin film, Health care, Poison control, Sputtering
Papers published on a yearly basis
Papers
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TL;DR: Postoperative cognitive dysfunction occurs frequently but resolves by 3 months after surgery, and may be associated with decreased activity during this period, as reported in subjective report overestimates the incidence.
Abstract: Background: Postoperative cognitive dysfunction (POCD) after noncardiac surgery is strongly associated with increasing age in elderly patients; middle-aged patients (aged 40-60 yr) may be expected to have a lower incidence, although subjective complaints are frequent. Metbods: The authors compared the changes in neuropsychological test results at 1 week and 3 months in patients aged 40-60 yr, using a battery of neuropsychological tests, with those of age-matched control subjects using Z-score analysis. They assessed risk factors and associations of POCD with measures of subjective cognitive function, depression, and activities of daily living. Results: At 7 days, cognitive dysfunction as defined was present in 19.2% (confidence interval [CI], 15.7-23.1) of the patients and in 4.0% (CI, 1.6-8.0) of control subjects (P < 0.001). After 3 months, the incidence was 6.2% (CI, 4.1-8.9) in patients and 4.1% (CI, 1.7-8.4) in control subjects (not significant). POCD at 7 days was associated with supplementary epidural analgesia and reported avoidance of alcohol consumption. At 3 months, 29% of patients had subjective symptoms of POCD, and this finding was associated with depression. Early POCD was associated with reports of lower activity scores at 3 months. Conclusions: Postoperative cognitive dysfunction occurs frequently but resolves by 3 months after surgery. It may be associated with decreased activity during this period. Subjective report overestimates the incidence of POCD. Patients may be helped by recognition that the problem is genuine and reassured that it is likely to be transient.
368 citations
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TL;DR: It seems prudent, where possible, to select antipsychotics that are not associated with marked QTc prolongation, and if use of a QTC-prolonging drug is warranted, then measures to reduce the risk should be adopted.
Abstract: Sudden unexpected deaths have been reported with antipsychotic use since the early 1960s. In some cases the antipsychotic may be unrelated to death, but in others it appears to be a causal factor. Antipsychotics can cause sudden death by several mechanisms, but particular interest has centred on torsade de pointes (TdP), a polymorphic ventricular arrhythmia that can progress to ventricular fibrillation and sudden death. The QTc interval is a heart rate-corrected value that represents the time between the onset of electrical depolarisation of the ventricles and the end of repolarisation. Prolongation of the QTc interval is a surrogate marker for the ability of a drug to cause TdP. In individual patients an absolute QTc interval of >500 msec or an increase of 60 msec from baseline is regarded as indicating an increased risk of TdP. However, TdP can occur with lower QTc values or changes.
363 citations
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TL;DR: The logistic-regression analyses indicated that even after the effects of personal vulnerability to psychiatric disorder and ongoing social stress outside of work had been taken into account, stressful situations at work contributed to anxiety and depressive disorders.
362 citations
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TL;DR: In this paper, a systematic classification of flow interference regimes is linked to the observed vortex shedding responses for a wide range of arrangements, and all types of the fluid-elastic oscillations were related to the regions of interference.
361 citations
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TL;DR: A phylogeographic analysis shows that DWV is globally distributed in honeybees, having recently spread from a common source, the European honeybee Apis mellifera, and exhibits epidemic growth and transmission that is predominantly mediated by European and North American honeybee populations and driven by trade and movement of honeybee colonies.
Abstract: Deformed wing virus (DWV) and its vector, the mite Varroa destructor, are a major threat to the world’s honeybees. Although the impact of Varroa on colony-level DWV epidemiology is evident, we have little understanding of wider DWV epidemiology and the role that Varroa has played in its global spread. A phylogeographic analysis shows that DWV is globally distributed in honeybees, having recently spread from a common source, the European honeybee Apis mellifera. DWV exhibits epidemic growth and transmission that is predominantly mediated by European and North American honeybee populations and driven by trade and movement of honeybee colonies. DWV is now an important reemerging pathogen of honeybees, which are undergoing a worldwide manmade epidemic fueled by the direct transmission route that the Varroa mite provides.
360 citations
Authors
Showing all 13134 results
Name | H-index | Papers | Citations |
---|---|---|---|
Hongjie Dai | 197 | 570 | 182579 |
Michael P. Lisanti | 151 | 631 | 85150 |
Matthew Jones | 125 | 1161 | 96909 |
David W. Denning | 113 | 736 | 66604 |
Wayne Hall | 111 | 1260 | 75606 |
Richard Gray | 109 | 808 | 78580 |
Christopher E.M. Griffiths | 108 | 671 | 47675 |
Thomas P. Davis | 107 | 724 | 41495 |
Nicholas Tarrier | 92 | 326 | 25881 |
David M. A. Mann | 88 | 338 | 43292 |
Ajith Abraham | 86 | 1113 | 31834 |
Federica Sotgia | 85 | 247 | 28751 |
Mike Hulme | 84 | 300 | 35436 |
Robert N. Foley | 84 | 260 | 31580 |
Richard Baker | 83 | 514 | 22970 |