Institution
University of São Paulo
Education•São Paulo, Brazil•
About: University of São Paulo is a education organization based out in São Paulo, Brazil. It is known for research contribution in the topics: Population & Context (language use). The organization has 136513 authors who have published 272320 publications receiving 5127869 citations. The organization is also known as: USP & Universidade de São Paulo.
Topics: Population, Context (language use), Medicine, Health care, Immune system
Papers published on a yearly basis
Papers
More filters
TL;DR: The results presented herewith show the efficiency of the proposed method for improving the enzymatic digestibility of sugarcane bagasse and provide understanding of the pretreatment action mechanism.
Abstract: Background
In recent years, biorefining of lignocellulosic biomass to produce multi-products such as ethanol and other biomaterials has become a dynamic research area Pretreatment technologies that fractionate sugarcane bagasse are essential for the successful use of this feedstock in ethanol production In this paper, we investigate modifications in the morphology and chemical composition of sugarcane bagasse submitted to a two-step treatment, using diluted acid followed by a delignification process with increasing sodium hydroxide concentrations Detailed chemical and morphological characterization of the samples after each pretreatment condition, studied by high performance liquid chromatography, solid-state nuclear magnetic resonance, diffuse reflectance Fourier transformed infrared spectroscopy and scanning electron microscopy, is reported, together with sample crystallinity and enzymatic digestibility
444 citations
TL;DR: Chicken myosin-V binds to and decorates F-actin, has actin-activated magnesium-ATPase activity, and is a barbed-end-directed motor capable of moving actin filaments at rates of up to 400 nm/s.
443 citations
TL;DR: In this article, mutations in POR encoding P450 oxidoreductase, the obligate electron donor for these enzymes, were identified in a woman with amenorrhea and three children with ABS.
Abstract: Deficient activities of multiple steroidogenic enzymes have been reported without and with Antley-Bixler syndrome (ABS), but mutations of corresponding cytochrome P450 enzymes have not been found. We identified mutations in POR, encoding P450 oxidoreductase, the obligate electron donor for these enzymes, in a woman with amenorrhea and three children with ABS, even though knock-out of POR is embryonically lethal in mice. Mutations of POR also affect drug-metabolizing P450 enzymes, explaining the association of ABS with maternal fluconazole ingestion.
443 citations
TL;DR: The findings establish the vagal gut-to-brain axis as an integral component of the neuronal reward pathway and suggest novel vagal stimulation approaches to affective disorders.
443 citations
TL;DR: The results reveal unique intra-tissue macrophage specialization and identify neuro-immune communication between enteric neurons and macrophages that induces rapid tissue-protective responses to distal perturbations.
442 citations
Authors
Showing all 138091 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| George M. Whitesides | 240 | 1739 | 269833 |
| Peter Libby | 211 | 932 | 182724 |
| Robert C. Nichol | 187 | 851 | 162994 |
| Paul M. Thompson | 183 | 2271 | 146736 |
| Terrie E. Moffitt | 182 | 594 | 150609 |
| Douglas R. Green | 182 | 661 | 145944 |
| Richard B. Lipton | 176 | 2110 | 140776 |
| Robin M. Murray | 171 | 1539 | 116362 |
| George P. Chrousos | 169 | 1612 | 120752 |
| David A. Bennett | 167 | 1142 | 109844 |
| Barry M. Popkin | 157 | 751 | 90453 |
| David H. Adams | 155 | 1613 | 117783 |
| Joao Seixas | 153 | 1538 | 115070 |
| Matthias Egger | 152 | 901 | 184176 |
| Ichiro Kawachi | 149 | 1216 | 90282 |