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Institution

University of Saskatchewan

EducationSaskatoon, Saskatchewan, Canada
About: University of Saskatchewan is a education organization based out in Saskatoon, Saskatchewan, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 25021 authors who have published 52579 publications receiving 1483049 citations. The organization is also known as: USask.


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Journal ArticleDOI
TL;DR: The literature search yielded 1865 citations with five studies meeting the selection criteria and 21 outcomes of which seven were designated as major outcomes: multidimensional function, self reported physical function, pain, tenderness, muscle strength, attrition rates, and adverse effects.
Abstract: Background Fibromyalgia is characterized by chronic widespread pain that leads to reduced physical function. Exercise training is commonly recommended as a treatment for management of symptoms. We examined the literature on resistance training for individuals with fibromyalgia. Resistance training is exercise performed against a progressive resistance with the intention of improving muscle strength, muscle endurance, muscle power, or a combination of these. Objectives To evaluate the benefits and harms of resistance exercise training in adults with fibromyalgia. We compared resistance training versus control and versus other types of exercise training. Search methods We searched nine electronic databases (The Cochrane Library, MEDLINE, EMBASE, CINAHL, PEDro, Dissertation Abstracts, Current Controlled Trials, World Health Organization (WHO) International Clinical Trials Registry Platform, AMED) and other sources for published full-text articles. The date of the last search was 5 March 2013. Two review authors independently screened 1856 citations, 766 abstracts and 156 full-text articles. We included five studies that met our inclusion criteria. Selection criteria Selection criteria included: a) randomized clinical trial, b) diagnosis of fibromyalgia based on published criteria, c) adult sample, d) full-text publication, and e) inclusion of between-group data comparing resistance training versus a control or other physical activity intervention. Data collection and analysis Pairs of review authors independently assessed risk of bias and extracted intervention and outcome data. We resolved disagreements between the two review authors and questions regarding interpretation of study methods by discussion within the pairs or when necessary the issue was taken to the full team of 11 members. We extracted 21 outcomes of which seven were designated as major outcomes: multidimensional function, self reported physical function, pain, tenderness, muscle strength, attrition rates, and adverse effects. We evaluated benefits and harms of the interventions using standardized mean differences (SMD) or mean differences (MD) or risk ratios or Peto odds ratios and 95% confidence intervals (CI). Where two or more studies provided data for an outcome, we carried out a meta-analysis. Main results The literature search yielded 1865 citations with five studies meeting the selection criteria. One of the studies that had three arms contributed data for two comparisons. In the included studies, there were 219 women participants with fibromyalgia, 95 of whom were assigned to resistance training programs. Three randomized trials compared 16 to 21 weeks of moderate- to high-intensity resistance training versus a control group. Two studies compared eight weeks of progressive resistance training (intensity as tolerated) using free weights or body weight resistance exercise versus aerobic training (ie, progressive treadmill walking, indoor and outdoor walking), and one study compared 12 weeks of low-intensity resistance training using hand weights (1 to 3 lbs (0.45 to 1.36 kg)) and elastic tubing versus flexibility exercise (static stretches to major muscle groups). Statistically significant differences (MD; 95% CI) favoring the resistance training interventions over control group(s) were found in multidimensional function (Fibromyalgia Impact Questionnaire (FIQ) total decreased 16.75 units on a 100-point scale; 95% CI -23.31 to -10.19), self reported physical function (-6.29 units on a 100-point scale; 95% CI -10.45 to -2.13), pain (-3.3 cm on a 10-cm scale; 95% CI -6.35 to -0.26), tenderness (-1.84 out of 18 tender points; 95% CI -2.6 to -1.08), and muscle strength (27.32 kg force on bilateral concentric leg extension; 95% CI 18.28 to 36.36). Differences between the resistance training group(s) and the aerobic training groups were not statistically significant for multidimensional function (5.48 on a 100-point scale; 95% CI -0.92 to 11.88), self reported physical function (-1.48 units on a 100-point scale; 95% CI -6.69 to 3.74) or tenderness (SMD -0.13; 95% CI -0.55 to 0.30). There was a statistically significant reduction in pain (0.99 cm on a 10-cm scale; 95% CI 0.31 to 1.67) favoring the aerobic groups. Statistically significant differences were found between a resistance training group and a flexibility group favoring the resistance training group for multidimensional function (-6.49 FIQ units on a 100-point scale; 95% CI -12.57 to -0.41) and pain (-0.88 cm on a 10-cm scale; 95% CI -1.57 to -0.19), but not for tenderness (-0.46 out of 18 tender points; 95% CI -1.56 to 0.64) or strength (4.77 foot pounds torque on concentric knee extension; 95% CI -2.40 to 11.94). This evidence was classified low quality due to the low number of studies and risk of bias assessment. There were no statistically significant differences in attrition rates between the interventions. In general, adverse effects were poorly recorded, but no serious adverse effects were reported. Assessment of risk of bias was hampered by poor written descriptions (eg, allocation concealment, blinding of outcome assessors). The lack of a priori protocols and lack of care provider blinding were also identified as methodologic concerns. Authors' conclusions The evidence (rated as low quality) suggested that moderate- and moderate- to high-intensity resistance training improves multidimensional function, pain, tenderness, and muscle strength in women with fibromyalgia. The evidence (rated as low quality) also suggested that eight weeks of aerobic exercise was superior to moderate-intensity resistance training for improving pain in women with fibromyalgia. There was low-quality evidence that 12 weeks of low-intensity resistance training was superior to flexibility exercise training in women with fibromyalgia for improvements in pain and multidimensional function. There was low-quality evidence that women with fibromyalgia can safely perform moderate- to high-resistance training.

222 citations

Journal ArticleDOI
TL;DR: This work reviews the experimental and theoretical progress in this field and reports on the discovery of two narrow charm-strange states and more excited heavy hadrons reported in 2003.
Abstract: Since the discovery of the first charmed meson in 1976, many open-charm and open-bottom hadrons were observed. In 2003 two narrow charm-strange states [Formula: see text] and D s1(2460) were discovered by the BaBar and CLEO Collaborations, respectively. After that, more excited heavy hadrons were reported. In this work, we review the experimental and theoretical progress in this field.

222 citations

Journal ArticleDOI
TL;DR: In this paper, the effect of moisture content on four pharmaceutical powders (an active pharmaceutical ingredient (API), Aspartame, Hydroxypropyl Methylcellulose (HPMC), and Respitose ML001) has been investigated.

222 citations

Journal ArticleDOI
TL;DR: The Fuping Complex as discussed by the authors comprises three major lithological assemblages: the ∼2.50 Ga trondhjemite-tonalite-granodiorite (TTG) gneisses, the Wanzi paragneisses and the 2.02 Ga Nanying granitic gneises.

222 citations

Journal ArticleDOI
TL;DR: In this article, the authors provide a descriptive and functional analysis of the diverse types of interorganizational institutional innovations with an eye toward achieving a more universal typology of the variations that exist.
Abstract: In recent years, collaborations, partnerships and networks have evolved as institutional innovations to address the integrated nature of complex policy problems. Understanding the variation in how these innovative institutions work, as well as what they do, is an important step in allowing managers to understand better the implications and applications of these arrangements. This article provides a descriptive and functional analysis of the diverse types of interorganizational institutional innovations with an eye toward achieving a more universal typology of the variations that exist. The article details the various applications for which these different institutional variants can be used and the contextual factors that affect them. The typology and functional analysis is useful for decision makers to assess the types of interorganizational institutional innovations they might want to adopt in a given situation.

222 citations


Authors

Showing all 25277 results

NameH-indexPapersCitations
Tomas Hökfelt158103395979
Frederick Wolfe119417101272
Christopher G. Goetz11665159510
John P. Giesy114116262790
Helmut Kettenmann10438040211
Paul M. O'Byrne10460556520
Susan S. Taylor10451842108
Keith A. Hobson10365341300
Mark S. Tremblay10054143843
James F. Fries10036983589
Gordon McKay9766161390
Jonathan D. Adachi9658931641
Wenjun Zhang9697638530
William C. Dement9634043014
Chris Ryan9597134388
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023173
2022350
20213,129
20202,913
20192,665
20182,479