Institution
University of Seville
Education•Seville, Andalucía, Spain•
About: University of Seville is a education organization based out in Seville, Andalucía, Spain. It is known for research contribution in the topics: Population & Model predictive control. The organization has 20098 authors who have published 47317 publications receiving 947007 citations. The organization is also known as: Universidad de Sevilla.
Topics: Population, Model predictive control, Control theory, Nonlinear system, Context (language use)
Papers published on a yearly basis
Papers
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TL;DR: Although progress in the field of communication for patients with LIS is promising, it is concluded that there are new possibilities to be pursued and that a more positive outlook in the area of professional care of the patients will facilitate new and positive strategies for this syndrome.
Abstract: A review of the scientific literature on locked-in syndrome (LIS) is offered. The clinical features, diagnosis and prognosis of LIS are reviewed, and methods regarding the differential diagnosis of LIS with severe disorders of consciousness are considered. Effective treatment, physiotherapy, and methods of communication are reviewed. Although progress in the field of communication for patients with LIS is promising, it is concluded that there are new possibilities to be pursued and that a more positive outlook in the area of professional care of the patients, as well as more extensive imaginative research will facilitate new and positive strategies for this syndrome.
141 citations
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TL;DR: Results indicate that human leptin receptor in circulating mononuclear cells has the signaling capacity to activate JAK-STAT cascade, which may mediate, at least in part, the action of human leptin in human peripheral blood monon nuclear cells.
141 citations
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TL;DR: In this paper, two solar power cycles are considered to power on MED-PF-TVC, MVC (multi effect distillation thermal and mechanical vapor compressions) processes.
141 citations
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TL;DR: Melatonin influences telomerase both in vivo and in vitro, decreasing its activity in the tumors of nude mice and the mRNA expression of the TERT and TR subunits, essential factors for the proper function of the telomere elongation enzyme.
Abstract: In this study for the first time the relationship between melatonin and telomerase activity was investigated. Melatonin exhibits oncostatic properties, but the actual mechanism of action by which the indole reduces tumor cell activity is not clear. Telomerase is an enzyme responsible of telomere elongation and is activated in most human cancers. In the current in vivo study, eight nude mice received a MCF-7 xenograft and thereafter they were treated for 5 weeks with 0.1 mg/mL of melatonin in the drinking water. Melatonin treatment caused a significant reduction in the weight of tumors and reduced metastases when compared with the control group. As indicated by the Telomerase Repeats Amplification Protocol (TRAP) assay, a significant decrease in telomerase activity was observed in the group treated with melatonin. In related in vitro studies, cultured MCF-7 cells were treated with three different concentrations of melatonin and a control without indole treatment. A significant dose-dependent decrease in Telomerase reverse transcriptase (TERT), the catalytic subunit of telomerase, mRNA expression was observed in the melatonin-treated cells. We also observed a significant reduction in TR, the RNA telomerase subunit, mRNA expression at physiological concentrations of melatonin (1 nm). Significant differences in TEP1, an associated telomerase protein, mRNA expression were also observed. In conclusion, melatonin influences telomerase both in vivo and in vitro, decreasing its activity in the tumors of nude mice and the mRNA expression of the TERT and TR subunits, essential factors for the proper function of the telomerase enzyme.
141 citations
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TL;DR: In this article, a mixing model was proposed to explain the petrogenesis of the Hercynian calc-alkaline granodiorites of Iberia, and a modified classification of common plutonic rocks in orogenic environments was proposed.
141 citations
Authors
Showing all 20465 results
Name | H-index | Papers | Citations |
---|---|---|---|
Russel J. Reiter | 169 | 1646 | 121010 |
Aaron Dominguez | 147 | 1968 | 113224 |
Jose M. Ordovas | 123 | 1024 | 70978 |
Detlef Lohse | 104 | 1075 | 42787 |
Miroslav Krstic | 95 | 955 | 42886 |
María Vallet-Regí | 95 | 711 | 41641 |
John S. Sperry | 93 | 160 | 35602 |
Jose Rodriguez | 93 | 803 | 58176 |
Shun-ichi Amari | 90 | 495 | 40383 |
Michael Ortiz | 87 | 467 | 31582 |
Bruce J. Paster | 84 | 261 | 28661 |
Floyd E. Dewhirst | 81 | 229 | 42613 |
Joan Montaner | 80 | 489 | 22413 |
Francisco B. Ortega | 79 | 503 | 26069 |
Luis Paz-Ares | 77 | 592 | 31496 |