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Institution

University of Seville

EducationSeville, Andalucía, Spain
About: University of Seville is a education organization based out in Seville, Andalucía, Spain. It is known for research contribution in the topics: Population & Model predictive control. The organization has 20098 authors who have published 47317 publications receiving 947007 citations. The organization is also known as: Universidad de Sevilla.


Papers
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Journal ArticleDOI
TL;DR: An overview of recent advances in the identification and use of bacterial enzymes acting on lignin or lignIn-derived products is provided, including DyP-type peroxidases and laccases.

393 citations

Journal ArticleDOI
TL;DR: In this article, a comprehensive review of the main innovations and future trends in the design of seawater reverse osmosis desalination technology is presented, with a special focus on the use of renewable energies as an innovation in the medium-term for medium and large production capacities.

385 citations

Journal ArticleDOI
TL;DR: The low‐gluten, transgene‐free wheat lines described here could be used to produce low-gluten foodstuff and serve as source material to introgress this trait into elite wheat varieties.
Abstract: Celiac disease is an autoimmune disorder triggered in genetically predisposed individuals by the ingestion of gluten proteins from wheat, barley, and rye. The -gliadin gene family of wheat contains four highly stimulatory peptides, of which the 33-mer is the main immunodominant peptide in celiac patients. We designed two sgRNAs to target a conserved region adjacent to the coding sequence for the 33-mer in the -gliadin genes. Twenty-one mutant lines were generated, all showing strong reduction in -gliadins. Up to 35 different genes were mutated in one of the lines of the 45 different genes identified in the wild type, while immunoreactivity was reduced by 85%. Transgene-free lines were identified, and no off-target mutations have been detected in any of the potential targets. The low-gluten, transgene-free wheat lines described here could be used to produce low gluten foodstuff and serve as source material to introgress this trait into elite wheat varieties. This article is protected by copyright. All rights reserved.

384 citations

Journal ArticleDOI
01 Jun 2020
TL;DR: The challenge hepatologists are facing is to promote telemedicine in the outpatient setting, prioritise outpatient contacts, avoid nosocomial dissemination of the virus to patients and healthcare providers, and at the same time maintain standard care for patients who require immediate medical attention.
Abstract: The coronavirus disease 2019 (COVID-19) pandemic poses an enormous challenge to healthcare systems in affected communities. Older patients and those with pre-existing medical conditions have been identified as populations at risk of a severe disease course. It remains unclear at this point to what extent chronic liver diseases should be considered as risk factors, due to a shortage of appropriate studies. However, patients with advanced liver disease and those after liver transplantation represent vulnerable patient cohorts with an increased risk of infection and/or a severe course of COVID-19. In addition, the current pandemic requires unusual allocation of healthcare resources which may negatively impact the care of patients with chronic liver disease that continue to require medical attention. Thus, the challenge hepatologists are facing is to promote telemedicine in the outpatient setting, prioritise outpatient contacts, avoid nosocomial dissemination of the virus to patients and healthcare providers, and at the same time maintain standard care for patients who require immediate medical attention.

384 citations

Journal ArticleDOI
TL;DR: In this article, the origin and the historic development of energy certification schemes in buildings along with the definition and scope of a building energy certificate and critical aspects of its implementation are discussed.

383 citations


Authors

Showing all 20465 results

NameH-indexPapersCitations
Russel J. Reiter1691646121010
Aaron Dominguez1471968113224
Jose M. Ordovas123102470978
Detlef Lohse104107542787
Miroslav Krstic9595542886
María Vallet-Regí9571141641
John S. Sperry9316035602
Jose Rodriguez9380358176
Shun-ichi Amari9049540383
Michael Ortiz8746731582
Bruce J. Paster8426128661
Floyd E. Dewhirst8122942613
Joan Montaner8048922413
Francisco B. Ortega7950326069
Luis Paz-Ares7759231496
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023143
2022567
20213,357
20203,480
20193,032
20182,766