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Institution

University of Siena

EducationSiena, Italy
About: University of Siena is a education organization based out in Siena, Italy. It is known for research contribution in the topics: Population & Cancer. The organization has 12179 authors who have published 33334 publications receiving 1008287 citations. The organization is also known as: Università degli studi di Siena & Universita degli studi di Siena.


Papers
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Journal ArticleDOI
TL;DR: A brief historical overview of the development of the concepts and theories of energy quality, and net energy that were the precursors to emergy is given in this paper, where the authors provide some insights into the types of processes and systems that have been evaluated using emergy methods.

431 citations

Journal ArticleDOI
TL;DR: Data indicate that autophagy is increased in neuronal cells after neonatal hypoxia-ischemia and suggest that over-activation of autophagic pathways represents a potential protective mechanism in the early stage of the brain injury.

431 citations

Book ChapterDOI
01 May 2001
TL;DR: In this paper, the authors propose a model of trust and deception for electronic commerce, which is based on the Trusted Third Party (Trusted third party) model. But in fact different kind of trust are needed and should be modelled and supported.
Abstract: As it was been written in the call of the original workshop “In recent research on electronic commerce” trust has been recognized as one of the key factors for successful electronic commerce adoption In electronic commerce problems of trust are magnified, because agents reach out far beyond their familiar trade environments Also it is far from obvious whether existing paper-based techniques for fraud detection and prevention are adequate to establish trust in an electronic network environment where you usually never meet your trade partner face to face, and where messages can be read or copied a million times without leaving any trace With the growing impact of electronic commerce distance trust building becomes more and more important, and better models of trust and deception are needed One trend is that in electronic communication channels extra agents, the so called Trusted Third Parties, are introduced in an agent community that take care of trust building among the other agents in the network But in fact different kind of trust are needed and should be modelled and supported: trust in the environment and in the infrastructure (the socio-technical system); trust in your agent and in mediating agents; trust in the potential partners; trust in the warrantors and authorities (if any)

431 citations

Journal ArticleDOI
B. P. Abbott1, Richard J. Abbott1, T. D. Abbott2, Fausto Acernese3  +1237 moreInstitutions (131)
TL;DR: In this paper, the authors place constraints on the dipole radiation and possible deviations from GR in the post-Newtonian coefficients that govern the inspiral regime of a binary neutron star inspiral.
Abstract: The recent discovery by Advanced LIGO and Advanced Virgo of a gravitational wave signal from a binary neutron star inspiral has enabled tests of general relativity (GR) with this new type of source. This source, for the first time, permits tests of strong-field dynamics of compact binaries in the presence of matter. In this Letter, we place constraints on the dipole radiation and possible deviations from GR in the post-Newtonian coefficients that govern the inspiral regime. Bounds on modified dispersion of gravitational waves are obtained; in combination with information from the observed electromagnetic counterpart we can also constrain effects due to large extra dimensions. Finally, the polarization content of the gravitational wave signal is studied. The results of all tests performed here show good agreement with GR.

430 citations

Journal ArticleDOI
TL;DR: Novel therapies such as targeted molecular therapies, agents targeting DNA damage response and metabolism, immunotherapies and viral therapies will be reviewed, as well as the current challenges and future directions for research.
Abstract: Glioblastomas are the most common form of malignant primary brain tumor and an important cause of morbidity and mortality. In recent years there have been important advances in understanding the molecular pathogenesis and biology of these tumors, but this has not translated into significantly improved outcomes for patients. In this consensus review from the Society for Neuro-Oncology (SNO) and the European Association of Neuro-Oncology (EANO), the current management of isocitrate dehydrogenase wildtype (IDHwt) glioblastomas will be discussed. In addition, novel therapies such as targeted molecular therapies, agents targeting DNA damage response and metabolism, immunotherapies, and viral therapies will be reviewed, as well as the current challenges and future directions for research.

429 citations


Authors

Showing all 12352 results

NameH-indexPapersCitations
Johan Auwerx15865395779
I. V. Gorelov1391916103133
Roberto Tenchini133139094541
Francesco Fabozzi133156193364
M. Davier1321449107642
Roberto Dell'Orso132141292792
Rino Rappuoli13281664660
Teimuraz Lomtadze12989380314
Manas Maity129130987465
Dezso Horvath128128388111
Paolo Azzurri126105881651
Vincenzo Di Marzo12665960240
Igor Katkov12597271845
Ying Lu12370862645
Thomas Schwarz12370154560
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202391
2022221
20211,870
20201,979
20191,639
20181,523