University of Siena

About: University of Siena is a education organization based out in Siena, Italy. It is known for research contribution in the topics: Population & Cancer. The organization has 12179 authors who have published 33334 publications receiving 1008287 citations. The organization is also known as: Università degli studi di Siena & Universita degli studi di Siena.

Biotechnology and the European public

Abstract: The latest European sample survey of public perceptions of biotechnology reveals widespread opposition to genetically modified (GM) food in much of Europe, but public attitudes to medical and environmental applications remain positive.

Growth in transition: what we know , what we don't, and what we should

Abstract: This essay surveys macroeconomic issues that marked the transition from planned to market economy in Central and Eastern European and former Soviet Union countries. We first establish stylized facts of the transition so far. We then critically survey the theoretical literature on transition, discussing explanations for the initial output fall, and mediumterm issues such as optimal speed of transition, disorganization, institutions and sectoral reallocation as source of output dynamics. We review the empirical literature to assess how well it translates the theoretical models and explains the stylized facts. We conclude with suggestions for future research.

Evidence-based guidelines: MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis--establishing disease prognosis and monitoring patients

Abstract: The role of MRI in the assessment of multiple sclerosis (MS) goes far beyond the diagnostic process. MRI techniques can be used as regular monitoring to help stage patients with MS and measure disease progression. MRI can also be used to measure lesion burden, thus providing useful information for the prediction of long-term disability. With the introduction of a new generation of immunomodulatory and/or immunosuppressive drugs for the treatment of MS, MRI also makes an important contribution to the monitoring of treatment, and can be used to determine baseline tissue damage and detect subsequent repair. This use of MRI can help predict treatment response and assess the efficacy and safety of new therapies. In the second part of the MAGNIMS (Magnetic Resonance Imaging in MS) network's guidelines on the use of MRI in MS, we focus on the implementation of this technique in prognostic and monitoring tasks. We present recommendations on how and when to use MRI for disease monitoring, and discuss some promising MRI approaches that may be introduced into clinical practice in the near future.

The role of biomarkers in environmental assessment (2). Invertebrates

Abstract: The potential use of biomarkers in ecological risk assessment is explored. The biomarker concept, initially developed to form a basis for studies at the individual/population level, is extended to include community and ecosystem level studies. A strategy is outlined in which biomarkers might be used to assess chemical exposureand the cumulative, adverse effects of toxicants on biotain situ. Protocols for identifying communities, species and populations most at risk are described. The role of biomarkers in the evaluation of the effectiveness of remedial action to alleviate pollution is discussed. It is proposed that, in addition to biomarker measurements on samples obtained from organisms at field sites, biomarker screening tests should be initiated in the laboratory with a range of new chemicals and organisms relevant to the field sites thought to be at risk. This will help to establish links between laboratory-based testing and adverse effectsin situ.