University of South Australia

About: University of South Australia is a education organization based out in Adelaide, South Australia, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 10086 authors who have published 32587 publications receiving 913683 citations. The organization is also known as: The University of South Australia & UniSA.

Australian school children's self appraisal of interpersonal relations : The bullying experience

Abstract: The extent and nature of bullying among South Australian primary school children and their self appraisals of peer relations were investigated in a survey of 412 primary school children between the ages of 7 to 13 years. It was found that 10% of boys and 6% of girls were subject to peer group bullying and for 8% of such children the bullying episodes lasted 6 months or more. Factor analysis of styles of interpersonal relating amongst children identified three independent factors including a tendency to bully, to be victimised and to act in a pro-social manner. The tendency to be victimised correlated negatively with self appraisals of the number of friends, popularity, happiness at school and feelings of safety at school. The findings are discussed in relation to research linking negative self appraisals of interpersonal competence with isolation and proneness to depression in later years.

RICOPILI: Rapid Imputation for COnsortias PIpeLIne.

Abstract: SUMMARY: Genome-wide association study (GWAS) analyses, at sufficient sample sizes and power, have successfully revealed biological insights for several complex traits. RICOPILI, an open-sourced Perl-based pipeline was developed to address the challenges of rapidly processing large-scale multi-cohort GWAS studies including quality control (QC), imputation and downstream analyses. The pipeline is computationally efficient with portability to a wide range of high-performance computing environments. RICOPILI was created as the Psychiatric Genomics Consortium pipeline for GWAS and adopted by other users. The pipeline features (i) technical and genomic QC in case-control and trio cohorts, (ii) genome-wide phasing and imputation, (iv) association analysis, (v) meta-analysis, (vi) polygenic risk scoring and (vii) replication analysis. Notably, a major differentiator from other GWAS pipelines, RICOPILI leverages on automated parallelization and cluster job management approaches for rapid production of imputed genome-wide data. A comprehensive meta-analysis of simulated GWAS data has been incorporated demonstrating each step of the pipeline. This includes all the associated visualization plots, to allow ease of data interpretation and manuscript preparation. Simulated GWAS datasets are also packaged with the pipeline for user training tutorials and developer work. AVAILABILITY AND IMPLEMENTATION: RICOPILI has a flexible architecture to allow for ongoing development and incorporation of newer available algorithms and is adaptable to various HPC environments (QSUB, BSUB, SLURM and others). Specific links for genomic resources are either directly provided in this paper or via tutorials and external links. The central location hosting scripts and tutorials is found at this URL: https://sites.google.com/a/broadinstitute.org/RICOPILI/home. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

In the flesh or online? Exploring qualitative research methodologies

Abstract: This article discusses the use of computer-mediated research techniques in a research project which investigates how people with disabilities engage with and use computer technologies. Identifying the rationale, process and experiences involved in the decision to engage in electronic research in this particular research topic will illuminate some limitations in traditional methods of qualitative data collection more generally. In responding to the opportunities presented by the information age, electronic research methods will substantially enhance the development of a more participatory research process. While incorporative research is imperative to the disability research agenda, the issue is no less critical to other aspects of the research enterprise.

Arsenic contamination in groundwater in the Southeast Asia region.

Abstract: The adverse impact of groundwater contaminated with arsenic (As) on humans has been reported worldwide, particularly in Asian countries. In this study, we present an overview of the As crisis in the Southeast Asian region where groundwater is contaminated with naturally occurring As and where contamination has become more widespread in recent years. In this region more than 100 million people are estimated to be at risk from groundwater As contamination, and some 700,000 people are known so far to have been affected by As-related diseases. Despite investments exceeding many millions of dollars, there are still substantial knowledge gaps about the prevalence and impact of As, notably in its epidemiology, temporal variations, social factors, patient identification, treatment, etc. Arsenic-affected people in the affected regions also face serious social problems. Of major concern is the fact that many researchers from different countries have been conducting research in SE Asia region but with a lack of coordination, thus duplicating their work. There is an urgent need to coordinate these various studies to ensure better delivery of research outcomes. Further research is needed to improve field testing and monitoring of drinking water sources, and to develop new treatments for chronic As toxicity and new sources of safe drinking water.