Showing papers by "University of South Carolina published in 2020"

The ATLAS Experiment at the CERN Large Hadron Collider

Abstract: The ATLAS detector as installed in its experimental cavern at point 1 at CERN is described in this paper. A brief overview of the expected performance of the detector when the Large Hadron Collider begins operation is also presented.

Mental Health Status Among Children in Home Confinement During the Coronavirus Disease 2019 Outbreak in Hubei Province, China.

Abstract: This cohort study investigates the depression and anxiety of children in Wuhan and Huangshi, Hubei province, China, during the coronavirus disease 2019 lockdown.

How artificial intelligence will change the future of marketing

Abstract: In the future, artificial intelligence (AI) is likely to substantially change both marketing strategies and customer behaviors. Building from not only extant research but also extensive interactions with practice, the authors propose a multidimensional framework for understanding the impact of AI involving intelligence levels, task types, and whether AI is embedded in a robot. Prior research typically addresses a subset of these dimensions; this paper integrates all three into a single framework. Next, the authors propose a research agenda that addresses not only how marketing strategies and customer behaviors will change in the future, but also highlights important policy questions relating to privacy, bias and ethics. Finally, the authors suggest AI will be more effective if it augments (rather than replaces) human managers.

Outcomes of Hydroxychloroquine Usage in United States Veterans Hospitalized with COVID-19.

Abstract: Summary Background Despite limited and conflicting evidence, hydroxychloroquine, alone or in combination with azithromycin, is widely used in COVID-19 therapy. Methods We performed a retrospective study of electronic health records of patients hospitalized with confirmed SARS-CoV-2 infection in US Veterans Health Administration medical centers between March 9, 2020 and April 29, 2020. Patients hospitalized within 24 h of diagnosis were classified based on their exposure to hydroxychloroquine alone (HC) or with azithromycin (HC+AZ) or no HC as treatments. The primary outcomes were mortality and use of mechanical ventilation. Findings A total of 807 patients were evaluated. Compared to the no HC group, after propensity score adjustment for clinical characteristics, the risk of death from any cause was higher in the HC group (adjusted hazard ratio [aHR], 1.83; 95% confidence interval [CI], 1.16–2.89; p = 0.009), but not in the HC+AZ group (aHR, 1.31; 95% CI, 0.80–2.15; p = 0.28). Both the propensity-score-adjusted risks of mechanical ventilation and death after mechanical ventilation were not significantly different in the HC group (aHR, 1.19; 95% CI, 0.78–1.82; p = 0.42 and aHR, 2.11; 95% CI, 0.96–4.62; p = 0.06, respectively) or in the HC+AZ group (aHR, 1.09; 95% CI, 0.72–1.66; p = 0.69 and aHR, 1.25; 95% CI, 0.59–2.68; p = 0.56, respectively) compared to the no HC group. Conclusions Among patients hospitalized with COVID-19, this retrospective study did not identify any significant reduction in mortality or in the need for mechanical ventilation with hydroxychloroquine treatment with or without azithromycin. Funding University of Virginia Strategic Investment Fund

Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19

Abstract: BACKGROUND: Despite limited and conflicting data on the use of hydroxychloroquine in patients with Covid-19, the U.S. Food and Drug Administration has authorized the emergency use of this drug when clinical trials are unavailable or infeasible. Hydroxychloroquine, alone or in combination with azithromycin, is being widely used in Covid-19 therapy based on anecdotal and limited observational evidence. METHODS: We performed a retrospective analysis of data from patients hospitalized with confirmed SARS-CoV-2 infection in all United States Veterans Health Administration medical centers until April 11, 2020. Patients were categorized based on their exposure to hydroxychloroquine alone (HC) or with azithromycin (HC+AZ) as treatments in addition to standard supportive management for Covid-19. The two primary outcomes were death and the need for mechanical ventilation. We determined the association between treatment and the primary outcomes using competing risk hazard regression adjusting for clinical characteristics via propensity scores. Discharge and death were taken into account as competing risks and subdistribution hazard ratios are presented. RESULTS: A total of 368 patients were evaluated (HC, n=97; HC+AZ, n=113; no HC, n=158). Rates of death in the HC, HC+AZ, and no HC groups were 27.8%, 22.1%, 11.4%, respectively. Rates of ventilation in the HC, HC+AZ, and no HC groups were 13.3%, 6.9%, 14.1%, respectively. Compared to the no HC group, the risk of death from any cause was higher in the HC group (adjusted hazard ratio, 2.61; 95% CI, 1.10 to 6.17; P=0.03) but not in the HC+AZ group (adjusted hazard ratio, 1.14; 95% CI, 0.56 to 2.32; P=0.72). The risk of ventilation was similar in the HC group (adjusted hazard ratio, 1.43; 95% CI, 0.53 to 3.79; P=0.48) and in the HC+AZ group (adjusted hazard ratio, 0.43; 95% CI, 0.16 to 1.12; P=0.09), compared to the no HC group. CONCLUSIONS: In this study, we found no evidence that use of hydroxychloroquine, either with or without azithromycin, reduced the risk of mechanical ventilation in patients hospitalized with Covid-19. An association of increased overall mortality was identified in patients treated with hydroxychloroquine alone. These findings highlight the importance of awaiting the results of ongoing prospective, randomized, controlled studies before widespread adoption of these drugs.

The COVID-19 Pandemic and Physical Activity

Abstract: The SARS-CoV-2-caused COVID-19 pandemic has resulted in a devastating threat to human society in terms of health, economy, and lifestyle. Although the virus usually first invades and infects the lung and respiratory track tissue, in extreme cases, almost all major organs in the body are now known to be negatively impacted often leading to severe systemic failure in some people. Unfortunately, there is currently no effective treatment for this disease. Pre-existing pathological conditions or comorbidities such as age are a major reason for premature death and increased morbidity and mortality. The immobilization due to hospitalization and bed rest and the physical inactivity due to sustained quarantine and social distancing can downregulate the ability of organs systems to resist to viral infection and increase the risk of damage to the immune, respiratory, cardiovascular, musculoskeletal systems and the brain. The cellular mechanisms and danger of this “second wave” effect of COVID-19 to the human body, along with the effects of aging, proper nutrition, and regular physical activity, are reviewed in this article.

Durability challenges of anion exchange membrane fuel cells

Abstract: As substantial progress has been made in improving the performance of anion exchange membrane fuel cells (AEMFCs) over the last decade, the durability of AEMFCs has become the most critical requirement to deploy competitive energy conversion systems. Because of different operating environments from proton exchange membrane fuel cells, several AEMFC-specific component degradations have been identified as the limiting factors influencing the AEMFC durability. In this article, AEMFC durability protocol, the current status of AEMFC durability, and performance degradation mechanisms are reported based on the discussion during the US Department of Energy (DOE) Anion Exchange Membrane Workshop at Dallas, Texas, May 2019. With additional recent progress, we provide our perspectives on current technical challenges and future action to develop long-lasting AEMFCs.

Resilience, Social Support, and Coping as Mediators between COVID-19-related Stressful Experiences and Acute Stress Disorder among College Students in China.

Abstract: BACKGROUND: The COVID-19 pandemic outbreak might induce acute stress disorder (ASD) to people living in the epidemic regions. The current study aims to investigate the association of COVID-19-related stressful experiences with ASD and possible psychological mechanisms of the association among college students. METHODS: Data were collected from 7,800 college students via an online survey during the initial stage of the COVID-19 outbreak in China (from 31 January to 11 February 2020). Existing scales were adapted to measure stressful experiences, resilience, coping, social support, and ASD symptoms. Path analysis was employed to examine the research hypotheses. RESULTS: Among the 7,800 college students, 61.53% were women and their mean age was 20.54 years. Both direct and indirect effects from COVID-19-related stressful experiences to ASD symptoms were significant. The relationship between COVID-19-related stressful experiences and ASD could be mediated by resilience (s = 0.01, p < .001), adaptive coping strategies (s = 0.02, p < .001), and social support (s = 0.01, p < .001); while not being significantly mediated by maladaptive coping strategies. CONCLUSION: The findings presented the ASD symptoms related to the COVID-19 outbreak and the mediating role of interpersonal and intrapersonal factors in the association. Identifying the risk and protective factors is important to reduce acute psychological responses.

Measurement of R (D) and R (D?) with a Semileptonic Tagging Method

Abstract: The experimental results on the ratios of branching fractions $\mathcal{R}(D) = {\cal B}(\bar{B} \to D \tau^- \bar{ u}_{\tau})/{\cal B}(\bar{B} \to D \ell^- \bar{ u}_{\ell})$ and $\mathcal{R}(D^*) = {\cal B}(\bar{B} \to D^* \tau^- \bar{ u}_{\tau})/{\cal B}(\bar{B} \to D^* \ell^- \bar{ u}_{\ell})$, where $\ell$ denotes an electron or a muon, show a long-standing discrepancy with the Standard Model predictions, and might hint to a violation of lepton flavor universality. We report a new simultaneous measurement of $\mathcal{R}(D)$ and $\mathcal{R}(D^*)$, based on a data sample containing $772 \times 10^6$ $B\bar{B}$ events recorded at the $\Upsilon(4S)$ resonance with the Belle detector at the KEKB $e^+ e^-$ collider. In this analysis the tag-side $B$ meson is reconstructed in a semileptonic decay mode and the signal-side $\tau$ is reconstructed in a purely leptonic decay. The measured values are $\mathcal{R}(D)= 0.307 \pm 0.037 \pm 0.016$ and $\mathcal{R}(D^*) = 0.283 \pm 0.018 \pm 0.014$, where the first uncertainties are statistical and the second are systematic. These results are in agreement with the Standard Model predictions within $0.2$, $1.1$ and $0.8$ standard deviations for $\mathcal{R}(D)$, $\mathcal{R}(D^*)$ and their combination, respectively. This work constitutes the most precise measurements of $\mathcal{R}(D)$ and $\mathcal{R}(D^*)$ performed to date as well as the first result for $\mathcal{R}(D)$ based on a semileptonic tagging method.

Photophysics Modulation in Photoswitchable Metal–Organic Frameworks

Abstract: In this Review, we showcase the upsurge in the development and fundamental photophysical studies of more than 100 metal-organic frameworks (MOFs) as versatile stimuli-responsive platforms. The goal is to provide a comprehensive analysis of the field of photoresponsive MOFs while delving into the underlying photophysical properties of various classes of photochromic molecules including diarylethene, azobenzene, and spiropyran as well as naphthalenediimide and viologen derivatives integrated inside a MOF matrix as part of a framework backbone, as a ligand side group, or as a guest. In particular, the geometrical constraints, photoisomerization rates, and electronic structures of photochromic molecules integrated inside a rigid MOF scaffold are discussed. Thus, this Review reflects on the challenges and opportunities of using photoswitchable MOFs in next-generation multifunctional stimuli-responsive materials while highlighting their use in optoelectronics, erasable inks, or as the next generation of sensing devices.

Elusive consensus: Polarization in elite communication on the COVID-19 pandemic.

Abstract: Cues sent by political elites are known to influence public attitudes and behavior Polarization in elite rhetoric may hinder effective responses to public health crises, when accurate information and rapid behavioral change can save lives We examine polarization in cues sent to the public by current members of the US House and Senate during the onset of the COVID-19 pandemic, measuring polarization as the ability to correctly classify the partisanship of tweets' authors based solely on the text and the dates they were sent We find that Democrats discussed the crisis more frequently-emphasizing threats to public health and American workers-while Republicans placed greater emphasis on China and businesses Polarization in elite discussion of the COVID-19 pandemic peaked in mid-February-weeks after the first confirmed case in the United States-and continued into March These divergent cues correspond with a partisan divide in the public's early reaction to the crisis

Single Cobalt Sites Dispersed in Hierarchically Porous Nanofiber Networks for Durable and High-Power PGM-Free Cathodes in Fuel Cells.

Abstract: Increasing catalytic activity and durability of atomically dispersed metal-nitrogen-carbon (M-N-C) catalysts for the oxygen reduction reaction (ORR) cathode in proton-exchange-membrane fuel cells remains a grand challenge. Here, a high-power and durable Co-N-C nanofiber catalyst synthesized through electrospinning cobalt-doped zeolitic imidazolate frameworks into selected polyacrylonitrile and poly(vinylpyrrolidone) polymers is reported. The distinct porous fibrous morphology and hierarchical structures play a vital role in boosting electrode performance by exposing more accessible active sites, providing facile electron conductivity, and facilitating the mass transport of reactant. The enhanced intrinsic activity is attributed to the extra graphitic N dopants surrounding the CoN4 moieties. The highly graphitized carbon matrix in the catalyst is beneficial for enhancing the carbon corrosion resistance, thereby promoting catalyst stability. The unique nanoscale X-ray computed tomography verifies the well-distributed ionomer coverage throughout the fibrous carbon network in the catalyst. The membrane electrode assembly achieves a power density of 0.40 W cm-2 in a practical H2 /air cell (1.0 bar) and demonstrates significantly enhanced durability under accelerated stability tests. The combination of the intrinsic activity and stability of single Co sites, along with unique catalyst architecture, provide new insight into designing efficient PGM-free electrodes with improved performance and durability.

Strategic CSR: A Concept Building Meta-Analysis

Abstract: This study develops the concept of Strategic Corporate Social Responsibility (Strategic CSR) by meta -analyzing the available empirical evidence on the relationship between CSR and corporate financial performance (CFP). Using meta -analytic structural equation modeling on effect size data from 344 primary studies, our study documents four empirical mechanisms explaining how CSR positively affects CFP: by 1) enhancing firm reputation, 2) increasing stakeholder reciprocation, 3) mitigating firm risk, and 4) strengthening innovation capacity. We propose these four mechanisms to identify four causally relevant attributes that allow us to conceptually distinguish Strategic CSR from CSR more generally. Our findings indicate that the four mechanisms combined explain 20 percent of the CSR -CFP relationship, suggesting that considerable room remains for future empirical research . The development of an empirically informed, causal conceptualization of Strategic CSR respond s to a long -heard call for better -specified concepts in empirical CSR research.

Early-onset colorectal cancer: initial clues and current views

Abstract: Over the past several decades, the incidence of early-onset colorectal cancer (EOCRC; in patients <50 years old) has increased at an alarming rate. Although robust and scientifically rigorous epidemiological studies have sifted out environmental elements linked to EOCRC, our knowledge of the causes and mechanisms of this disease is far from complete. Here, we highlight potential risk factors and putative mechanisms that drive EOCRC and suggest likely areas for fruitful research. In addition, we identify inconsistencies in the evidence implicating a strong effect of increased adiposity and suggest that certain behaviours (such as diet and stress) might place nonobese and otherwise healthy people at risk of this disease. Key risk factors are reviewed, including the global westernization of diets (usually involving a high intake of red and processed meats, high-fructose corn syrup and unhealthy cooking methods), stress, antibiotics, synthetic food dyes, monosodium glutamate, titanium dioxide, and physical inactivity and/or sedentary behaviour. The gut microbiota is probably at the crossroads of these risk factors and EOCRC. The time course of the disease and the fact that relevant exposures probably occur in childhood raise important methodological issues that are also discussed. The incidence of early-onset colorectal cancer (in patients <50 years old) is increasing at an alarming rate. This Review highlights potential risk factors and putative mechanisms that drive this disease, and suggests likely areas for fruitful research, including diet, stress and antibiotics.

Catalytic upcycling of high-density polyethylene via a processive mechanism

Abstract: The overconsumption of single-use plastics is creating a global waste catastrophe, with widespread environmental, economic and health-related consequences. Here we show that the benefits of processive enzyme-catalysed conversions of biomacromolecules can be leveraged to affect the selective hydrogenolysis of high-density polyethylene into a narrow distribution of diesel and lubricant-range alkanes using an ordered, mesoporous shell/active site/core catalyst architecture that incorporates catalytic platinum sites at the base of the mesopores. Solid-state nuclear magnetic resonance revealed that long hydrocarbon macromolecules readily move within the pores of this catalyst, with a subsequent escape being inhibited by polymer–surface interactions, a behaviour that resembles the binding and translocation of macromolecules in the catalytic cleft of processive enzymes. Accordingly, the hydrogenolysis of polyethylene with this catalyst proceeds processively to yield a reliable, narrow and tunable stream of alkane products. Achieving plastic deconstruction with high selectivity is crucial for upcycling schemes, but remains challenging. Here, a processive approach for the selective hydrogenolysis of high-density polyethylene into narrow alkane fractions is introduced relying on a Pt/SiO2 catalyst encapsulated in a mesoporous silica shell.

Volume I. Introduction to DUNE

Abstract: The preponderance of matter over antimatter in the early universe, the dynamics of the supernovae that produced the heavy elements necessary for life, and whether protons eventually decay—these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our universe, its current state, and its eventual fate. The Deep Underground Neutrino Experiment (DUNE) is an international world-class experiment dedicated to addressing these questions as it searches for leptonic charge-parity symmetry violation, stands ready to capture supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector technical design report (TDR) describes the DUNE physics program and the technical designs of the single- and dual-phase DUNE liquid argon TPC far detector modules. This TDR is intended to justify the technical choices for the far detector that flow down from the high-level physics goals through requirements at all levels of the Project. Volume I contains an executive summary that introduces the DUNE science program, the far detector and the strategy for its modular designs, and the organization and management of the Project. The remainder of Volume I provides more detail on the science program that drives the choice of detector technologies and on the technologies themselves. It also introduces the designs for the DUNE near detector and the DUNE computing model, for which DUNE is planning design reports. Volume II of this TDR describes DUNE's physics program in detail. Volume III describes the technical coordination required for the far detector design, construction, installation, and integration, and its organizational structure. Volume IV describes the single-phase far detector technology. A planned Volume V will describe the dual-phase technology.

CSR in Times of Crisis: Evidence from the COVID-19 Pandemic

Abstract: The debate over how firm stakeholder engagement is tied to preserving shareholder wealth has received growing attention in recent years, especially in the wake of the COVID-19 crisis. Against this backdrop, we examine the relation between corporate social responsibility (CSR) and stock market returns during the COVID-19 pandemic-induced market crash and the post-crash recovery. Using a sample of 1,750 U.S. firms and two major sources of CSR ratings, we find no evidence that CSR affected stock returns during the crash period. This result is robust to various sensitivity tests. In additional cross-sectional analysis, we find some supporting evidence, albeit weak, that the relation between CSR and stock returns during the pandemic-related crisis is more positive when CSR is congruent with a firm’s institutional environment. We also find that Business Roundtable companies, which committed to protecting stakeholder interests prior to the pandemic, do not outperform during the pandemic crisis. We conclude that pre-crisis CSR is not effective at shielding shareholder wealth from the adverse effects of a crisis, suggesting a potential disconnect between firms’ CSR orientation (ratings) and actual actions. Our evidence suggests that investors can distinguish between genuine CSR and firms engaging in cheap talk.

Twitter reveals human mobility dynamics during the COVID-19 pandemic.

Abstract: The current COVID-19 pandemic raises concerns worldwide, leading to serious health, economic, and social challenges. The rapid spread of the virus at a global scale highlights the need for a more harmonized, less privacy-concerning, easily accessible approach to monitoring the human mobility that has proven to be associated with viral transmission. In this study, we analyzed over 580 million tweets worldwide to see how global collaborative efforts in reducing human mobility are reflected from the user-generated information at the global, country, and U.S. state scale. Considering the multifaceted nature of mobility, we propose two types of distance: the single-day distance and the cross-day distance. To quantify the responsiveness in certain geographic regions, we further propose a mobility-based responsive index (MRI) that captures the overall degree of mobility changes within a time window. The results suggest that mobility patterns obtained from Twitter data are amenable to quantitatively reflect the mobility dynamics. Globally, the proposed two distances had greatly deviated from their baselines after March 11, 2020, when WHO declared COVID-19 as a pandemic. The considerably less periodicity after the declaration suggests that the protection measures have obviously affected people's travel routines. The country scale comparisons reveal the discrepancies in responsiveness, evidenced by the contrasting mobility patterns in different epidemic phases. We find that the triggers of mobility changes correspond well with the national announcements of mitigation measures, proving that Twitter-based mobility implies the effectiveness of those measures. In the U.S., the influence of the COVID-19 pandemic on mobility is distinct. However, the impacts vary substantially among states.

Global, regional, and national burden of calcific aortic valve and degenerative mitral valve diseases, 1990-2017

Abstract: Background: Nonrheumatic valvular diseases are common; however, no studies have estimated their global or national burden. As part of the Global Burden of Disease Study 2017, mortality, prevalence,...

Catalytic Advantages, Challenges, and Priorities in Alkaline Membrane Fuel Cells

Abstract: Recently, anion exchange membrane fuel cells (AEMFCs) have seen a significant growth in research and practical interest as the achievable current density, peak power density, and longevity of state...

The construct of institutional distance through the lens of different institutional perspectives : Review, analysis, and recommendations

Abstract: This paper presents a review and critique of the 20-year-old literature on institutional distance, which has greatly proliferated. We start with a discussion of the three institutional perspectives that have served as a theoretical foundation for this construct: organizational institutionalism, institutional economics, and comparative institutionalism. We use this as an organizing framework to describe the different ways in which institutional distance has been conceptualized and measured, and to analyze the most common organizational outcomes that have been linked to institutional distance, as well as the proposed explanatory mechanisms of those effects. We substantiate our qualitative review with a meta-analysis, which synthesizes the main findings in this area of research. Building on our review and previous critical work, we note key ambiguities in the institutional distance literature related to underlying theoretical perspectives and associated mechanisms, distance versus profile effects, and measurement. We conclude with actionable recommendations for improving institutional distance research.

Erratum: The Belle II Physics Book (Progress of Theoretical and Experimental Physics (2019) 2019 (123C01) DOI: 10.1093/ptep/ptz106)

Abstract: In the original version of this manuscript, an error was introduced on pp352. '2.7nb:1.6nb' has been corrected to '2.4nb:1.3nb' in the current online and printed version. doi:10.1093/ptep/ptz106.

Achieving High-Performance and 2000 h Stability in Anion Exchange Membrane Fuel Cells by Manipulating Ionomer Properties and Electrode Optimization

Abstract: DOI: 10.1002/aenm.202001986 and component manufacturing costs, which are driven by the fact that PEMFCs require specialized component materials due to the highly acidic operating environment. To alleviate these costs, anion exchange membrane fuel cells (AEMFCs) have recently emerged as an alternative to PEMFCs. The higher pH operating environment offers several advantages such as lower material and manufacturing costs. For example, AEMFCs can use platinum group metal (PGM) free cathodes, have more facile oxygen reduction kinetics,[3,4] and may enable a wider range of fuels (e.g., methanol, hydrazine). However, early AEMFC developments suffered from very low overall performance and durability.[5,6] From a durability perspective, cells were mostly believed to be limited by chemical degradation of the anion exchange membrane (AEM) and ionomer at high pH. Because of this, there has been a significant amount of investment targeting the design and manufacturing of stable AEMs and ionomers. As a result, several AEMs have been shown to be stable both at elevated temperature (≥80 °C) and pH for hundreds or even thousands of hours during ex situ testing.[7–11] Another issue that has started to be addressed in the AEMFC literature is water management. Water is formed at the AEMFC hydrogen anode and consumed at the oxygen cathode. As water is produced at the anode, it must be removed to avoid flooding—either through the anode gas stream or, preferably, through the AEM to the cathode (via backdiffusion) where it is needed to react.[12] If too little water is supplied to the cathode by back-diffusion it can dry out; if more water arrives to the cathode than can be reacted, it is also possible for the cathode to flood. Therefore, there is a need for both the anode and cathode catalyst layers to be able to passively transport water. The ability of the ionomer in the catalyst layer to facilitate such ion transport is related to the overall hydrophilicity of the monomers used in the polymer membranes and ionomer. One example where ionomer water uptake has been limiting is the well-known ethylene-tetrafluoroethylene copolymer (ETFE) based powder ionomer.[13] Though the ion exchange capacity (IEC) of that material is modest (only 1.24 meq g−1), The primary function of the ionomers that are incorporated into fuel cell electrode catalyst layers is to provide pathways for ion transport between the catalyst active sites and the electrolyte. This is influenced by many variables, including the ion-exchange capacity, water uptake, and molecular weight. In anion exchange membrane fuel cells (AEMFCs), controlling ionomer water uptake is particularly important and tailoring this property in each electrode is an important consideration when looking to maximize cell performance. In this study, three poly(norbornene) tetrablock copolymer ionomers with a range of physical properties are synthesized and incorporated into AEMFC anode and cathode electrodes. Systematic electrode engineering with these ionomers allows the peak power density to be increased by 100% (1.6 W cm-2 → 3.2 W cm-2) and the current density at 0.2 V to be increased by 59% (5.9 A cm-2 → 9.4 A cm-2). Moreover, the top-performing electrode configuration is tested in an operating AEMFC at the US Department of Energy defined current density of 600 mA cm-2 for 2000 h, showing a record-low voltage decay rate of 15.36 μV h-1 – only 3.65% –a over 2000 h. This work sets a new bar for AEMFCs, reporting the best combination of performance and durability of any AEMFC to date.

The Cortical Organization of Syntax.

Abstract: Syntax, the structure of sentences, enables humans to express an infinite range of meanings through finite means. The neurobiology of syntax has been intensely studied but with little consensus. Two main candidate regions have been identified: the posterior inferior frontal gyrus (pIFG) and the posterior middle temporal gyrus (pMTG). Integrating research in linguistics, psycholinguistics, and neuroscience, we propose a neuroanatomical framework for syntax that attributes distinct syntactic computations to these regions in a unified model. The key theoretical advances are adopting a modern lexicalized view of syntax in which the lexicon and syntactic rules are intertwined, and recognizing a computational asymmetry in the role of syntax during comprehension and production. Our model postulates a hierarchical lexical-syntactic function to the pMTG, which interconnects previously identified speech perception and conceptual-semantic systems in the temporal and inferior parietal lobes, crucial for both sentence production and comprehension. These relational hierarchies are transformed via the pIFG into morpho-syntactic sequences, primarily tied to production. We show how this architecture provides a better account of the full range of data and is consistent with recent proposals regarding the organization of phonological processes in the brain.