University of St Andrews

About: University of St Andrews is a education organization based out in St Andrews, Fife, United Kingdom. It is known for research contribution in the topics: Population & Laser. The organization has 16260 authors who have published 43364 publications receiving 1636072 citations. The organization is also known as: St Andrews University & University of St. Andrews.

Harps-N: the new planet hunter at TNG

Abstract: The Telescopio Nazionale Galileo (TNG)[9] hosts, starting in April 2012, the visible spectrograph HARPS-N. It is based on the design of its predecessor working at ESO's 3.6m telescope, achieving unprecedented results on radial velocity measurements of extrasolar planetary systems. The spectrograph's ultra-stable environment, in a temperature-controlled vacuum chamber, will allow measurements under 1 m/s which will enable the characterization of rocky, Earth-like planets. Enhancements from the original HARPS include better scrambling using octagonal section fibers with a shorter length, as well as a native tip-tilt system to increase image sharpness, and an integrated pipeline providing a complete set of parameters. Observations in the Kepler field will be the main goal of HARPS-N, and a substantial fraction of TNG observing time will be devoted to this follow-up. The operation process of the observatory has been updated, from scheduling constraints to telescope control system. Here we describe the entire instrument, along with the results from the first technical commissioning.

Frequency of Solar-Like Systems and of Ice and Gas Giants Beyond the Snow Line from High-Magnification Microlensing Events in 2005-2008

Abstract: We present the first measurement of planet frequency beyond the "snow line" for planet/star mass-ratios[-4.5 200) microlensing events during 2005-8. The sample host stars have typical mass M_host 0.5 Msun, and detection is sensitive to planets over a range of projected separations (R_E/s_max,R_E*s_max), where R_E 3.5 AU sqrt(M_host/Msun) is the Einstein radius and s_max (q/5e-5)^{2/3}, corresponding to deprojected separations ~3 times the "snow line". Though frenetic, the observations constitute a "controlled experiment", which permits measurement of absolute planet frequency. High-mag events are rare, but the high-mag channel is efficient: half of high-mag events were successfully monitored and half of these yielded planet detections. The planet frequency derived from microlensing is a factor 7 larger than from RV studies at factor ~25 smaller separations [2

From normal response to clinical problem: definition and clinical features of fear of cancer recurrence

Abstract: Purpose Research to date on fear of cancer recurrence (FCR) shows that moderate to high FCR affects 22–87 % of cancer survivors and is associated with higher psychological morbidity (Simard et al J Cancer Surviv 7:300–322, 2013). Despite growing research interest in FCR, the lack of consensus on its definition and characteristics when it reaches a clinical level has impeded knowledge transfer into patient services.

Theorizing engagement: the potential of a critical dialogic approach

Abstract: Purpose – The purpose of this paper is to contribute to discussions about engagement in social and environmental accounting, drawing on dialogic theory and philosophy. A dialogic approach, building on existing critical inquiries, is introduced to derive principles to inform “on the ground” engagements. Applying dialogic thinking to social and environmental accounting encourages the development of dialogic forms of accountability, more authentic engagements and is more likely to contribute to sustainable social and environmental change.Design/methodology/approach – Contains a synthesis of literature from within and beyond social and environmental accounting to shed light on the issues addressed by the special issue.Findings – Research engagements in social and environmental accounting need not be taken in a haphazard manner uninformed by theory. In particular, the “learning turn” in social sciences has generated a large body of theorizing (informed by concrete engagement activities) that can be used to sha...

Na+, K+-ATPase isozyme diversity; comparative biochemistry and physiological implications of novel functional interactions.

Abstract: Na+, K+-ATPase is ubiquitously expressed in the plasma membrane of all animal cells where it serves as the principal regulator of intracellular ion homeostasis. Na+, K+-ATPase is responsible for generating and maintaining transmembrane ionic gradients that are of vital importance for cellular function and subservient activities such as volume regulation, pH maintenance, and generation of action potentials and secondary active transport. The diversity of Na+, K+-ATPase subunit isoforms and their complex spatial and temporal patterns of cellular expression suggest that Na+, K+-ATPase isozymes perform specialized physiological functions. Recent studies have shown that the alpha subunit isoforms possess considerably different kinetic properties and modes of regulation and the beta subunit isoforms modulate the activity, expression and plasma membrane targeting of Na+, K+-ATPase isozymes. This review focuses on recent developments in Na+, K+-ATPase research, and in particular reports of expression of isoforms in various tissues and experiments aimed at elucidating the intrinsic structural features of isoforms important for Na+, K+-ATPase function.